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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

Displaying 196031 - 196040 of 207731 results
  1. Topic 373: Monoclonal Antibodies to RNA-modifications

    SBC: ABZYME THERAPEUTICS LLC            Topic: NCI

    Post-transcriptional RNA modification is quite complex as there are more than sixty known RNA modifications that occur in thousands of RNAs in eukaryotic cells. A number of these RNA modifications have been shown to influence the development and physiology of the central nervous system (CNS) and to be involved in carcinogenesis. Despite the growing interest in and importance of RNA modifications, ...

    SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  2. Topic 378: mPROS: Mobile PRO-CTCAE Administration System for Post-Radiation Toxicities

    SBC: Intelligent Automation, Inc.            Topic: NCI

    The problems this contract is addressing include making it easy for patients to report toxicities after radiation therapy so that they can be timely and accurate and so that they can be incorporated into a medical database for use by medical professionals. This would allow the app to recommend (when appropriate), and for clinicians to intervene, with appropriate treatments and will lead to better ...

    SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  3. TOPIC 421: MULTI-COMPARTMENT PHANTOM MATERIALS FOR QUANTITATIVE, MULTI-PARAMETIC MRI OF THE PROSTATE

    SBC: COMPUTERIZED IMAGING REFERENCE SYSTEMS, INC.            Topic: 421

    Prostate cancer (PCa) remains a leading malignancy for the US male population, with over 200,000 new cases projected in 2020. Multi-parametric (mpMRI) is the current standard-of-care to diagnose and triage indolent versus aggressive PCa for treatment according to PIRADS criteria. However, mpMRI diagnosis is based on a qualitative assessment that does not quantify the inherently multi-exponential d ...

    SBIR Phase I 2021 Department of Health and Human ServicesNational Institutes of Health
  4. TOPIC 383: MULTI-CORE BIOPSY DEVICE WITH VOLUMETRIC FIELD OF TISSUE ACQUISITION (MOONSHOT)

    SBC: ROBIN MEDICAL INC            Topic: NCI

    The problemTumor recurrence or resistance to treatment often arises due to tumor heterogeneityThere is a need to develop smart biopsy devicesto collect biopsies from multiple tumor coresto identify locations of the biopsiesto maintain physical characteristics of tumor on the extracted samplesto be used under current image guided practicesWe propose to further develop a prototype of multi core biop ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  5. TOPIC 383: MULTI-CORE BIOPSY DEVICE WITH VOLUMETRIC FIELD OF TISSUE ACQUISITION (MOONSHOT)

    SBC: ROBIN MEDICAL INC            Topic: 383

    The problem: Tumor recurrence or resistance to treatment often arises due to tumor heterogeneity. There is a need to develop smart biopsy devices: 1) to collect biopsies from multiple tumor cores; 2) to identify locations of the biopsies; 3) to maintain physical characteristics of tumor on the extracted samples; 4) to be used under current image-guided practices. We propose to further develop a pr ...

    SBIR Phase II 2020 Department of Health and Human ServicesNational Institutes of Health
  6. TOPIC 363: myCare2- Supporting Caregivers and Caregiving

    SBC: BRIGHTOUTCOME INC            Topic: NCI

    The myCare2 solution will be marketed to cancer care organizations and include three separate portals for cancer caregivers, patients and providers. The system will be mobile-enabled and support standards-based EHR integration. Primary myCare2 features include symptom assessment, communication with the care team, care plan dissemination, tailored education content for caregiving and for caregiver ...

    SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  7. TOPIC 424- MYH 2.0: A DIGITAL EXPERIENCE TO IMPROVE SURVIVORSHIP AMONG AYA CANCER SURVIVORS

    SBC: Radiant Creative Group, LLC            Topic: 424

    Adolescent and Young Adult (AYA) cancer survivors are expected to assume primary responsibility for their healthcare when they reach adulthood. However, only a minority (lt18%) of adult childhood cancer survivors obtain risk-based follow-up care. Transition readiness is a critical precursor to adult self-management of care, and adult self-management improves health status and reduces healthcare ut ...

    SBIR Phase I 2021 Department of Health and Human ServicesNational Institutes of Health
  8. TOPIC 428- NCI SBIR TRANSITION TO PHASE II SOLICITATION FY 2023

    SBC: EARLYDIAGNOSTICS INC            Topic: 428

    Integrative analysis of multi-omics datasets is revolutionizing cancer research and patient care. To take advantage of the full breadth of CRDC’s petabyte-scale data, EarlyDx will seamlessly integrate its liquid biopsy cloud-computing platform with CRDC data repositories. Liquid biopsies provide a non-invasive approach for interrogating the genomic and epigenomic profiles of tumors. Co-analysis ...

    SBIR Phase II 2023 Department of Health and Human ServicesNational Institutes of Health
  9. TOPIC 343: NEUROPSYCHOLOGICAL ASSESSMENT SYSTEM FOR CANCER PATIENTS

    SBC: CREARE LLC            Topic: NCI

    Cognitive decline is a major quality of life concern for many cancer survivorsThevarious available treatments affect individuals differentlyand research has unfortunately provided little guidance on how specific treatments impact neurocognitive functionTo help researchers fill this information gap and ultimately provide guidance to doctors and patientsa neuropsychological assessment system that is ...

    SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  10. TOPIC 396: NON-INVASIVE DETECTION OF HUMAN CD8+ T CELLS: A PET-BASED APPROACH TO ASSESS THE HUMAN IMMUNESYSTEM- MOONSHOT

    SBC: Revela Biotech LLC            Topic: NCI

    Immunotherapy has shown impressive success in treating several cancershoweverresponses to treatment are variableand predicting the response to therapy remains a major obstacleBiopsy analyses has correlated good prognosis with infiltration of CDT cells into the tumor and recent preclinical work suggests that tracking of CDT cells in tumors using single domain antibodyVHHbased PET imaging can accura ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
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