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A NEED EXISTS FOR BETTER DEVICES AND NEW INSTRUMENTS TO ENHANCE DIAGNOSTICS AND FOR APPLICATION TO PHYSIOLOGY AND PHARMACOLOGY AS OUTLINED IN THE PROGRAM SPECIFICATIONS FOR NINCDS AND NIGMS. THE PROPOSED WORK WILL STUDY THE ENGINEERING VARIABLES AND APPLICATIONS OF COULOMETRIC ELECTRODES IN SERIES FOR LIQUID CHROMATOGRAPHY ELECTROCHEMICAL (LCEC) DETECTOR SYSTEMS (N-ELECTRODE LCEC). SERIES COULOMET ...

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IMMOBILIZED ENZYMES SHOW PROMISE AS INDUSTRIAL AND BIOMEDI- CAL CATALYSTS. HOWEVER, WIDESPREAD ADOPTION OF THESE CATALYTIC MATERIALS IN THE CHEMICAL AND MEDICAL INDUSTRIES REQUIRES IMPROVED IMMOBILIZATION TECHNOLOGY THAT WILL IMPROVE THE STABILITY OF THE BIOCATALYST. THE ENZYME TECHNOLOGY RESEARCH GROUP, INC., LOCATED IN THE RESEARCH TRIANGLE OF NORTH CAROLINA, IS CARRYING OUT RESEARCH ON CARRAGEE ...

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OPTICAL FIBERS ARE BEING CONSIDERED IN THE DESIGNS OF MANY MILITARY SYSTEMS BECAUSE OF THE NUMEROUS ADVANTAGES INCLUDING EMP AND EMI. HIGH BANDWWIDTH AND/OR LONG RUN SYSTEMS REQUIRES GRADED INDEX FIBERS. ALL COMMERCIALLY AVAILABLE FIBERS SHOW HIGH PERMANENT AND TRANSIENT RADIATION INDUCED OPTICAL LOSSES AND, THEREFORE, DO NOT MET THE NUCLEAR VULNERABILITY REQUIREMENTS OF MANY SYSTEMS. THIS PROGRAM ...

FIBER OPTICS ARE NOW BEING USED TO TRANSMIT IN THE FORM OF OPTICAL ENERGY WITH CONVERSION TO HEAT AT THE TARGET SITE. THE PRIMARY APPLICATIONS IN MEDICAL SITUATIONS ARE THOSE WHERE ACCESS IS LIMITED AND THE SIZE OF THE TARGET AREA IS SMALL. HIGH DELIVERED POWER IS REQUIRED FOR OPTIC FIBERS TO BE USEFUL IN APPLICATIONS SUCH AS CUTTING AND WELDING AND MILITARY APPLICATIONS. EXISTING FIBERS ARE LIMIT ...

BECAUSE OF EXTENDED USE OF OLDER AIRFRAMES, INCREASED MISSION REQUIREMENTS SUCH AS MORE SEVERE CATAPULTS AND ARRESTMENTS, AND ADOPTION OF MORE BRITTLE ALLOYS, MONITORING OF FATIGUE DAMAGE ACCUMULATION AT PARTICULAR LOCATIONS ON MILITARY AIRCRAFT HAS BECOME IMPORTANT. WHILE NO SMALL, SELF-CONTINED DATA RECORDERS FOR USE IN MILITARY ENVIRONMENTS ARE PRESENTLY AVAILABLE, ADVANCES IN LOW-POWER CMOS CI ...

VISION TESTING IS PRESENTLY IN A STAGE OF FLUX BASED ON AUTOMATION AND COMPUTER IMPLEMENTATION OF CLINICAL AND EXPERIMENTAL TASKS, AND A NUMBER OF AGENCIES HAVE ACKNOWLEDGED THE NEED FOR AN ORGANIZED, CENTRALIZED, AND AUTOMATED BATTERY OF VISION TESTS THAT ADEQUATELY INDEX THE VARIOUS DIMENSIONS OF VISUAL FUNCTION. AS A NECESSARY PRELIMINARY STEP TO THIS GENERAL GOAL, A SURVEY OF EXTANT VISUAL PER ...

GRADUAL PROGRESS HAS BEEN ACHIEVED IN USING AS WORKLOAD INDICATORS A VARIETY OF ELECTROPHYSIOLOGICAL TECHNIQUES, INCLUDING EEG AND NEURAL EVOKED POTENTIALS. THESE TECHNIQUES TEND TO BE INTRUSIVE, RELATIVELY ARTIFICIAL, AND NON-PORTABLE. THERE MAY BE MORE READILY OBTAINABLE MEASURES THAT CAN SERVE AS SIMPLE EXTERNAL INDICANTS OF NEURAL ACTIVITY, BROADENING THE ABILITY TO CAPTURE CNS-RELATED VARIANC ...

AN INNOVATIVE PERFORMANCE MEASUREMENT METHODOLOGY IS PROPOSED TO PERMIT MEANINGFUL ANALYSIS OF TEST/EVALUATION CRITERIAL FOR MAN/MACHINE COMBINATIONS. THREE AREAS: INDIVIDUAL DIFFERENCES (HUMAN BASIC CAABILITIES, APTITUDES), PRACTICE EFFECTS (INSTRUCTION AND TRAINING) AND CRITERIA FOR HUMAN ENGINEERING OF EQUIPMENT DESIGN WILL BE TREATED AS VARIABLES AND WILL BE SET OFF IN EXPERIMENTAL APPOSITION ...