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Award Data

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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

Displaying 196051 - 196060 of 207726 results
  1. Reducing Complement Inhibition to Treat Leukemia and Lymphoma

    SBC: Compliment Corporation            Topic: NCI

    DESCRIPTION (provided by applicant): The funding of the application will yield safety and efficacy data on a new combination cancer therapy for leukemia and lymphomas. Monoclonal antibodies (mAbs) have emerged as a class of novel oncology therapeutics. Weare developing a molecule that can improve the therapeutic effects of mAbs by: 1) increasing the sensitivity of cancers to treatment 2) unmaskin ...

    SBIR Phase I 2011 Department of Health and Human ServicesNational Institutes of Health
  2. Targeted Treatment of Recurrent Small Cell Lung Cancer with Anti-AbnV2 Antibodies

    SBC: Woomera Therapeutics, Inc.            Topic: NCI

    DESCRIPTION (provided by applicant): The objective of this Phase 1 project is to improve an effective treatment of recurrent small-cell lung cancer (rSCLC) by targeting a tumor-specific abnormal receptor, AbnV2 that is a surface-marker of the disease. Currently, there is no effective treatment for rSCLC. Our data show expression of this abnormal vasopressin V2 receptor (AbnV2 ) is a common featur ...

    SBIR Phase I 2011 Department of Health and Human ServicesNational Institutes of Health
  3. Preclinical Development of iRGD for Pancreatic Cancer

    SBC: ASPYRIAN THERAPEUTICS, INC.            Topic: NCI

    DESCRIPTION (provided by applicant): The goal of this phase I SBIR proposal is to generate the pharmacokinetic and pharmacodynamic data required to support the filing of an Investigational New Drug application (IND) to the Food and Drug Administration (FDA), of the tumor-penetrating peptide iRGD, in combination with gemcitabine as a new treatment for pancreatic cancer. Pancreatic cancer is a key f ...

    SBIR Phase I 2011 Department of Health and Human ServicesNational Institutes of Health
  4. Developing a plectin-1 targeted imaging agent for the detection of pancreatic can

    SBC: iTi Health            Topic: NCI

    DESCRIPTION (provided by applicant): Pancreatic ductal adenocarcinoma (PDAC) is an intractable clinical problem, typically presenting with metastasis at the time of diagnosis and exhibiting profound resistance to existing therapies. Currently, the standarddiagnostic course includes CT or MRI scans which do not have optimal sensitivity and specificity for accurately diagnosing and determining resec ...

    SBIR Phase I 2011 Department of Health and Human ServicesNational Institutes of Health
  5. Trans-illumination of visible light for real-time catheter visualization

    SBC: LUMOS CATHETER SYSTEMS, INC.            Topic: NCI

    DESCRIPTION (provided by applicant): The peripherally inserted central catheter (PICC) is a ubiquitous tool used in hospitals worldwide to allow patients to more safely and efficiently receive strong medicines, concentrated nutrition and/or long-term intravenous fluids. PICCs begin in a peripheral vein, typically in the arm or leg, and are then advanced through a vein until the tip of the cathet ...

    SBIR Phase I 2011 Department of Health and Human ServicesNational Institutes of Health
  6. Protease chain reactions for molecular analysis of cancer markers

    SBC: POTOMAC AFFINITY PROTEIN LLC            Topic: NCI

    DESCRIPTION (provided by applicant): Our objective is to develop a protease chain reaction technology (ProCR) which will enable ultra- sensitive molecular detection. A protease chain reaction has four basic components: 1) a protease conjugated to a bindingmolecule, 2) an unconjugated protease, 3) an inhibitor protein which contains a proteolytic cleavage site and 4) a protease substrate which gene ...

    SBIR Phase I 2011 Department of Health and Human ServicesNational Institutes of Health
  7. High Throughput Method to Assess SNP Functionality in Prostate Cancer

    SBC: Proteovista LLC            Topic: NCI

    DESCRIPTION (provided by applicant): A critical unmet need in implementing personalized medicine is the ability to sort through the millions of single nucleotide polymorphisms (SNPs) present in the human genome and to pinpoint which of these DNA variations are causative in disease. A key under-studied function of SNPs is their ability to generate or disrupt genomic binding sites for transcription ...

    SBIR Phase I 2011 Department of Health and Human ServicesNational Institutes of Health
  8. Ading color to cancer, adenovirus and flow cytometry to identify and capture CTCs

    SBC: NANOCELLECT BIOMEDICAL INC            Topic: NCI

    DESCRIPTION (provided by applicant): We propose a novel technique to identify and capture circulating tumor cells (CTCs) using engineered adenoviruses and sophisticated flow cytometry. Current techniques for detection of CTCs include reverse transcriptase-polymerase chain reaction (RT-PCR), flow cytometry, fluorescence in situ hybridization, and, more recently, microfluidics. Unfortunately, RT-PCR ...

    SBIR Phase I 2011 Department of Health and Human ServicesNational Institutes of Health
  9. Web-Based Dissemination of Evidence-Based Prevention to U.S. Military

    SBC: National Health Promotion Associates, Inc.            Topic: NIDA

    DESCRIPTION (provided by applicant): This Phase I SBIR grant application requests six months of funding to develop and feasibility test an innovative Web-based distribution channel for increasing the dissemination, adoption, implementation, and sustainability (DAIS) of evidence-based substance use prevention programs to United States military personnel. Substance use and abuse, particularly heavy ...

    SBIR Phase I 2011 Department of Health and Human ServicesNational Institutes of Health
  10. Online Training on Opioid Overdose Prevention, Recognition, and Response

    SBC: SOCIAL SCIENCES INNOVATIONS CORPORATION            Topic: NIDA

    DESCRIPTION (provided by applicant): We propose to translate a successful, efficacious, CASAC-approved overdose prevention, recognition and response training curriculum (S.K.O.O.P-Skills and Knowledge on Overdose Prevention) utilized in NY State into an online Computer-Assisted Instructional (CAI) format to significantly impact the dissemination of this life- saving, community-based curriculum, na ...

    SBIR Phase I 2011 Department of Health and Human ServicesNational Institutes of Health
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