Award Data

The Department of Energy (DOE) is interested in innovative research involving fiber-optic radiation detectors and associated signal processing electronics for the identification of specific radioisotopes. Specifically, the DOE is keenly interested in new fiber-optic instrumentation to be used to detect, identify, and measure ionizing radiation produced by radionuclides trapped in decomissioned ste ...

To address NASA's need for alternative methods for ambient preservation of human biological samples collected during extended spaceflight and planetary operations, Chromologic (CL) proposes to develop a novel Biological Sample Ambient Preservation (BioSAP) device. BioSAP device is based on an improved dried biological specimens storage approach and specialized matrix to (1) collect a known am ...

Human plasma offers the promise of a revolution in biomarker-based disease diagnosis and therapeutic monitoring. Absence of a trained phlebotomist in remote locations limits the diagnostic potential of the human proteome, as current self-administered point-of-care extraction volumes are insufficient for the detection of many of the low abundance biomarkers. Current devices for monitoring glucose l ...

To address the Office of the Secretary of Defense, Defense Health Program"s (OSD/DHP) need for an innovative concept for effective, objective diagnosis of subjective tinnitus in military personnel, ChromoLogic (CL) proposes to develop the OPical TINnitus Assessment or (OPTINAS) system based on Near Infrared Optical system that quickly, easily, and inexpensively assesses level of neuronal activity ...

To address the Army"s need for an innovative concept for non-invasive, compact, robust monitoring system to monitor the oxidative status of military personnel, ChromoLogic (CL) proposes to develop the OCular Oxidative Stress Monitor (OCOSMO) technology based on non-invasive optical measurements of oxidative stress biomarkers that occur within the aqueous humor. The unique scientific expertise of C ...

The Army seeks a novel and practical approach for the collection and long-term preservation of RNA and other nucleic acids (e.g., microRNA, DNA) from blood products at near room temperature conditions. To address this unmet need, ChromoLogic, LLC, (CL) proposes to develop an Integrated Membrane for Preservation of RNA Transcripts (IMPRiNT) that utilizes relatively small sample sizes coupled to mem ...

The parasite Plasmodium vivax, transmitted by the Anopheles mosquito, is the second major cause of malaria worldwide and the major cause of malaria outside Africa. The infection is characterized by a chronic course of malaria with acute episodes of relapse after months to years of asymptomatic dormancy. Research focusing on P. vivax has been hindered by lack of a practical continuous culture syste ...

DESCRIPTION (provided by applicant): Although there are ~300,000 to 600,000 individuals in the United States with active uveitis, there is no clinically accepted method for quantitative assessment of ocular flare that would result in rapid, non-invasive diagnosis of uveitis. Current methods of diagnosis for uveitis involve a thorough examination of the eye with a slit lamp microscope and ophthalmo ...

Counterfeit parts, by definition are substandard, which compromises long life-cycle systems overseen by the Missile Defense Agency (MDA). Recent investigations by the Senate Armed Services Committee uncovered 1800 cases of suspected counterfeit electronic parts, with the total number of counterfeit parts exceeding 1,000,000. Putative solutions to the counterfeit electronics problem include both i ...

The Army seeks a novel and practical approach for the collection and long-term preservation of RNA and other nucleic acids (e.g., microRNA, DNA) from blood products at ambient conditions. Nucleic acids form the basis of numerous diagnostics and long-term health monitoring military protocols and are critical to ensure battle readiness. To address this unmet need, ChromoLogic, LLC, (CL) developed an ...