Award Data

THE DATA COLLECTION FOR THE MILLIMETER WAVELENGTH INSTRUMENTATION RADAR, BASED ON THE KWAJALEIN ATOLL, COULD BE SIGNIFICANTLY ENHANCED IF THE RADAR IS MODIFIED TO PROVIDE A LIMITED FIELD OF VIEW (LFOV) CAPABILITY. THIS WOULD ALLOW THE RADAR TO HAVE THE SAME CAPABILITY AS A FULL PHASED ARRAY OVER A LIMITED ANGLE COVERAGE WHICH WOULD MEAN MORE THAN ONE TARGET COULD BE TRACKED AT A TIME. THE APPROACH ...

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DESCRIPTION (provided by applicant): Cancer is the leading cause of mortality in the United States, despite many advances in the current therapies including surgery, radiation and chemotherapy. Therefore, it is imperative that novel targets for cancer therapeutic development are identified and explored in order to improve the outcome of this lethal disease. We recently exclusively licensed a novel ...

DESCRIPTION (provided by applicant): Natural products possess the richest source of molecular diversity in existence. In the case of cancer therapeutics, natural products have yielded a significant number of novel and effective cancer treatment and prevent ive agents. As a commercial venture, BCN Biosciences has a commitment to identifying new chemical structures from plants and fungi, and the dev ...

DESCRIPTION (provided by applicant): In a screen for naturally occurring angiogenic inhibitors, we have identified an extract from the plant Livistona chinensis, which has potent anti-angiogenic and anti-tumor activity and is non-toxic in mice. To our know ledge, ours is the first publication in the English literature on this extract from Livistona chinensis. We hypothesize that the Livistona extr ...

ABSTRACT: This proposal entitled A dual acting drug for enhancing radiotherapeutic benefit is designed to provide proof of concept evidence that the novel compound EWA001 can protect normal lung tissue from radiation-induced damage within an in vivo model without appreciably protecting neoplastic tissue. The protection of radiation induced lung toxicity from ionizing radiation and in particular ...

Approximatelymillion people are currently living with human immunodeficiency virusHIVinfection worldwideWith no curative therapy on the horizonpatients must be on antiretroviral therapyARTfor decades to manage their diseaseBecause ART targets only actively replicating virustreatment interruption or ART failure leads to rebound of latent virusRNA therapeutics have shown great promise as a new mecha ...

DESCRIPTION (provided by applicant): In order to reduce rates of preventable blindness, screening for treatable eye diseases has become increasingly important as the population ages in the United States and around the world. Early detection and diagnosis is vital to preserve retinal and optic nerve function. Currently, routine eye examinations are performed by highly skilled practitioners usi ...

This Small Business Innovation Research Phase I project develops a high speed and high sensitivity system for measuring optical dimensions of human eye, such as the total axial length, corneal thickness and the location and thickness of the crystalline lens, in a non-contact manner using infrared light, invisible to the eye. This task is accomplished by improving the existing technique of time dom ...