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The Award database is continually updated throughout the year. As a result, data for FY22 is not expected to be complete until September, 2023.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

Displaying 196081 - 196090 of 201422 results
  1. VACCINE POTENTIAL OF TOXOPLASMA GONDII RECOMBINANT P3

    SBC: Paravax Inc.            Topic: N/A

    N/A

    SBIR Phase I 1991 Department of Health and Human Services
  2. VACCINES DESIGNED FROM ANALYSIS OF RECENT HIV INFECTIONS

    SBC: VAXGEN, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): An effective vaccine is the only practical way to halt the AIDS epidemic. The greatest challenge in developing an effective HIV vaccine is antigenic variation. Therefore, the present project aim is to enhance the understanding of antigenic variation by characterizing intra-subtype sequence variation among gpl20 genes from incident (new) infections, and identi ...

    SBIR Phase I 2002 Department of Health and Human ServicesNational Institutes of Health
  3. Vaccines Designed From Analysis of Recent HIV Infections

    SBC: VAXGEN, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): An effective vaccine is the only practical way to halt the AIDS epidemic. The greatest challenge in developing an effective HIV vaccine is antigenic variation. Therefore, the present project aim is to enhance the understanding of antigenic variation by characterizing intra-subtype sequence variation among gpl20 genes from incident (new) infections, and identi ...

    SBIR Phase II 2003 Department of Health and Human ServicesNational Institutes of Health
  4. Vaccines for Eastern and Western Equine Encephalitis Viruses

    SBC: MAXYGEN, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Venezuelan, eastern, and western equine encephalitis viruses (VEEV, EEEV, WEEV respectively) are arthropod-borne alphaviruses that cause periodic epizootics in the Americas. No licensed vaccines exist for these pathogens, and the experimental vaccines used under Investigational New Drug status suffer from high reactogenicity or poor immunogenicity. Vaccines aga ...

    SBIR Phase I 2006 Department of Health and Human ServicesNational Institutes of Health
  5. Vaccine Strategies for Candidal Infections

    SBC: NOVADIGM THERAPEUTICS, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Candida is a fungus that is among the most common causes of infections in hospitalized patients in the United States and worldwide. Candida spp. are one of the most common microbes that infect the blood and urine of hospitalized patients. The cost associated with Candida blood infections alone exceeds at least $1 billion per year in the US. Even with therapy, 4 ...

    STTR Phase I 2006 Department of Health and Human ServicesNational Institutes of Health
  6. Vaccine Strategies for Candidal Infections

    SBC: NOVADIGM THERAPEUTICS, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Candida is a fungus that is among the most common causes of infections in hospitalized patients in the United States and worldwide. Candida spp. are one of the most common microbes that infect the blood and urine of hospitalized patients. The cost associated with Candida blood infections alone exceeds at least $1 billion per year in the US. Even with therapy, 4 ...

    SBIR Phase I 2006 Department of Health and Human ServicesNational Institutes of Health
  7. Vaccine Strategies for Candidal Infections

    SBC: NOVADIGM THERAPEUTICS, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Candida species are opportunistic fungal pathogens that have become among the most common causes of nosocomial infections in the United States and worldwide. Disseminated infections caused by Candida spp. have increased 15-fold in incidence in the last 15 years, and Candida is now the third most common cause of bloodstream infections. Even with modern antifunga ...

    STTR Phase II 2009 Department of Health and Human ServicesNational Institutes of Health
  8. Vaccine therapy of congenital adrenal Hyperplasia

    SBC: L2 Diagnostics, LLC            Topic: N/A

    N/A

    STTR Phase I 2003 Department of Health and Human ServicesNational Institutes of Health
  9. VACCINE TO TREAT CHRONIC HEPATITIS B VIRUS INFECTION

    SBC: Cytel Corp.            Topic: N/A

    HEPATITIS B VIRUS (HBV) IS A HEPATOTROPIC VIRUS THAT IS A MAJOR PUBLIC HEALTH CONCERN WORLDWIDE. WHILE A RECOMBINANT SURFACE ANTIGEN VACCINE IS AVAILABLE, THERE IS NO EFFECTIVE TREATMENT FOR THE MILLIONS OF INDIVIDUALS WHO ARE CHRONICALLY INFECTED. THE OBJECTIVE IS TO DEVELOP PEPTIDE THERAPEUTICS THAT WILL GENERATE CYTOTOXIC T LYMPHOCYTES (CTL) IN VIVO AND MAY AMELEIORATE CHRONIC HBV INFECTIONS. T ...

    SBIR Phase II 1995 Department of Health and Human Services
  10. VACCINE TO TREAT CHRONIC HEPATITIS B VIRUS INFECTION

    SBC: Cytel Corp.            Topic: N/A

    N/A

    SBIR Phase I 1992 Department of Health and Human Services
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