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The Award database is continually updated throughout the year. As a result, data for FY23 is not expected to be complete until September, 2024.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

Displaying 196091 - 196100 of 202203 results
  1. Open Path Analyzer for Accurate, ppt-level Quantification of EtO via Mid-Infrared Cavity Enhanced Spectrometry

    SBC: NIKIRA LABS INC.            Topic: 2A

    In this Small Business Innovation Research effort, Nikira Labs Inc. proposes to develop a sensitive (

    SBIR Phase II 2022 Environmental Protection Agency
  2. Developing an Ideal First Use Agent to Prevent Sepsis in Trauma Wounds During Care Under Fire

    SBC: Altrazeal LIfe Sciences Inc.            Topic: A20137

    Sepsis is the greatest danger after hemorrhage in both civilian and combat-related injuries with mortality rates ranging between 19.5 - 23%. Early intervention with appropriate antibiotics, hemodynamic optimization, and supportive care are particularly vital in preventing trauma related sepsis. Treatments to prevent trauma sepsis may be confounded by the uncontrolled bleeding which often atte ...

    SBIR Phase I 2021 Department of DefenseArmy
  3. Developing an Ideal First Use Agent to Prevent Sepsis in Trauma Wounds During Care Under Fire

    SBC: Altrazeal LIfe Sciences Inc.            Topic: A20137

    Sepsis is the greatest danger after hemorrhage in both civilian and combat-related injuries with mortality rates ranging between 19.5 - 23%. Early intervention with appropriate antibiotics, hemodynamic optimization, and supportive care are particularly vital in preventing trauma related sepsis. Treatments to prevent trauma sepsis may be confounded by the uncontrolled bleeding which often attends s ...

    SBIR Phase II 2022 Department of DefenseDefense Health Agency
  4. Cyclic Flow Cytometry for Ultra-High Marker Single-Cell Analysis

    SBC: LASE INNOVATION INC            Topic: 400

    Project Summary/Abstract Quantifying the presence, function, and fate of different immune cells is crucial in immunology and immuno- oncology research, as well as in the diagnosis of hematologic disorders. Flow cytometry is the current method of choice to measure different proteins expressed by single cells at high throughput. However, spectral overlap between fluorophore labels makes flow measure ...

    SBIR Phase I 2020 Department of Health and Human ServicesNational Institutes of Health
  5. Sample Barcoding for Ultra High-Throughput Flow Cytometry

    SBC: LASE INNOVATION INC            Topic: 400

    Project Summary High-throughput screens are the workhorse of the early drug discovery process. Millions of biochemical or cell-based assays are conducted to test the activity of small molecules, antibodies and oWher compoXndV Wo idenWif\ ³hiWV´ or drXg candidaWeV for fXrWher study, including pre-clinical and clinical studies. However, the most used technologies for high-throughput screening, suc ...

    SBIR Phase I 2021 Department of Health and Human ServicesNational Institutes of Health
  6. Cyclic Flow Cytometry for Ultra-High Marker Single-Cell Analysis

    SBC: LASE INNOVATION INC            Topic: 400

    Abstract Quantifying the presence, function, and fate of different immune cells is crucial in immunology research and development of immunotherapies. Flow cytometry is a single-cell technique that is widely used to measure different protein markers expressed by immune cells at high throughput. However, spectral overlap between fluorophore labels makes measurement of more than 20 markers difficult, ...

    SBIR Phase II 2021 Department of Health and Human ServicesNational Institutes of Health
  7. Single clone discovery using an image-based cell isolation platform

    SBC: ENRICH BIOSYSTEMS INC            Topic: NIAID

    Under microscopeit is easy to identify cells of specific morphological phenotypes or interacting with other cell typesBut it is not trivial to pick the very cell out without submicron precision mechanical instrumentmicro pipetting or laser micro dissectionTo facilitate image based single cell isolationwe seek to develop an LCD aided selection under microscopeLASUMtechnology that will allow us to p ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  8. Single clone discovery using an image-based cell isolation platform

    SBC: ENRICH BIOSYSTEMS INC            Topic: NIAID

    Abstract Characterizing both functional and genetic heterogeneity among a pool of cells remains a major scientific challenge in immunology, cancer research, neurobiology and developmental biology. Isolating cells with the same phenotype is key to understand such heterogeneity. We would like to develop a non-fluidic, unique technology, LCD aided selection under microscope (LASUM, Fig.1) to address ...

    SBIR Phase II 2020 Department of Health and Human ServicesNational Institutes of Health
  9. SBIR PHASE I TOPIC #439- ADVANCED SAMPLE PROCESSING PLATFORMS FOR DOWNSTREAM SINGLE-CELL MULTI-OMIC ANALYSIS

    SBC: ENRICH BIOSYSTEMS INC            Topic: 439

    The long term goal of this proposal is to develop a fast, hands-free platform that integrates tissue dissociation, clone characterization and isolation to support the growing field of single celll multiomics. During the phase I of the proposal, enrich will adapt the exiting image based, debris-resistant clone isolation machine by developing essential reagents, protocols and consumables for in-plac ...

    SBIR Phase I 2022 Department of Health and Human ServicesNational Institutes of Health
  10. Trustworthy Sustainment Solutions via a Learning-Assisted Digital Twin

    SBC: POINTPRO INC            Topic: AF21ATCSO1

    PointPro, Inc. offers a computational platform that performs adaptive, closed-loop predictive simulations in order to support the Air Force in its sustainment operations. The future of sustainment is in prescriptive analytics: predicting what will fail, when & how it will fail, and, what can be done about it? Prescriptive analytics demands timely, accurate forecasts of a system’s path to failure ...

    STTR Phase I 2021 Department of DefenseAir Force
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