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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

Displaying 196091 - 196100 of 207728 results
  1. TOPIC 1-Q OF THE DEPARTMENT OF DEFENSE OMNIBUS SOLICITATION SPECIFIES THE MEASUREMENT OF LIQUID WATER CONTENT OF SNOW.

    SBC: Maranatha Research, Ltd.            Topic: N/A

    TOPIC 1-Q OF THE DEPARTMENT OF DEFENSE OMNIBUS SOLICITATION SPECIFIES THE MEASUREMENT OF LIQUID WATER CONTENT OF SNOW. NUCLEAR MAGNETIC RESDNANCE SPECTROSCOPY HAS THE ABILITY TO DETECT AND MEASURE LIQUID CONTENT WITHOUT MEASURING SOLID DENSITY. FORTUNATELY THE HYDROGEN RESONANCE SIGNAL FROM H20 IS PROBABLY THE STRONGEST NMR SIGNAL AVAILABLE. THIS COMBINATION OF CIRCUMSTANCES SHOULD PERMIT THE DESI ...

    SBIR Phase I 1983 Department of DefenseArmy
  2. TOPIC 442: QUANTITATIVE TRACEABLE REFERENCE MATERIALS AS MDDTS FOR TISSUE BIOMARKERS

    SBC: BOSTON CELL STANDARDS INC.            Topic: 442

    This goal of this project is to qualify the first system of reference standards and measurement traceability in immunohistochemistry (IHC) testing as a Medical Device Development Tool (MDDT), topic 442. In all other types of laboratory testing, such as clinical chemistry, these metrologic tools are a standard of laboratory practice. FDA requires test manufacturers to identify methods of assay cali ...

    SBIR Phase I 2022 Department of Health and Human ServicesNational Institutes of Health
  3. Topic 349: Quantum Dot FRET Immunoassay to Quantify Intramolecular Epitopes of Analytes in Tissue Sections

    SBC: Ocean Nanotech LLC            Topic: NCI

    This proposal is to develop a novel slide based proximity assay platform to quantify protein phosphorylation on tissues. The novelty of this assay platform is derived from the use of the quantum dot with two emission peaks for fluorescence resonance energy transfer (FRET): one emission as internal standard and the other as FRET donor. Change of ratio of the two emission intensity during the FRET c ...

    SBIR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health
  4. TOPIC 428 ""Accessible Cloud-Based Multi-Omic and Imaging Analysis for the Cancer Research Data Commons""

    SBC: BIODEPOT LLC            Topic: 428

    Different types of high-throughput data are available in various databases for the cancer community. Integrating multi-omics and imaging data offers great potential in facilitating clinical decisions and discovery of therapeutic treatments for cancer patients. Cloud computing has emerged as a solution to address challenges of storing and analyzing these big data. However, rapid evolution of tools ...

    SBIR Phase I 2021 Department of Health and Human ServicesNational Institutes of Health
  5. TOPIC 419 ""BIOMARKERAWARE: A NOVEL SYSTEM TO IMPROVE PRECISION ONCOLOGY""

    SBC: CARE PROGRESS LLC            Topic: 419

    This research project seeks to create novel software to enable oncology providers to more easily identify cancer patients who could benefit from somatic, next-generation sequencing. It will also help providers interpret and explain results, which could alter clinical decision-making, including identifying potential therapeutic targets, ultimately improving clinical outcomes and enhancing patient-c ...

    SBIR Phase I 2021 Department of Health and Human ServicesNational Institutes of Health
  6. TOPIC 428 ""CLOUD-BASED LIQUID-BIOPSY PLATFORM FOR THE CANCER RESEARCH DATA COMMONS

    SBC: OMICSCRAFT LLC            Topic: 428

    Recent advances in cloud-based resources and technologies for multi-omics and imaging analysis have created new opportunities for exploring relationships between histology, molecular events, and clinical outcomes using quantitative methods. However, the unprecedented scale and complexity of multi-omics and imaging data have presented critical computational bottlenecks requiring new concepts and en ...

    SBIR Phase I 2021 Department of Health and Human ServicesNational Institutes of Health
  7. TOPIC 428 ""CLOUD-BASED LIQUID-BIOPSY PLATFORM FOR THE CANCER RESEARCH DATA COMMONS""

    SBC: EARLYDIAGNOSTICS INC            Topic: 428

    Integrative analysis of multi-omics datasets is revolutionizing cancer research and patient care. To take advantage of the full breadth of CRDC’s petabyte-scale data, EarlyDx will seamlessly integrate its liquid biopsy cloud-computing platform, a cfDNA–based bioinformatics platform with proprietary machine learning algorithms, with the CRDC data repositories and computational capacity in a clo ...

    SBIR Phase I 2021 Department of Health and Human ServicesNational Institutes of Health
  8. TOPIC 418 ""HIGH THROUGHPUT SPATIALOMICS PROFILING FOR THICK TUMOR TISSUES""

    SBC: Arvetas Biosciences, Inc.            Topic: 418

    A critical barrier to constructing molecular and cellular tumor atlases is the lack of spatialomics tools that can rapidly and cost-effectively profile multi-omics in large and thick tumor tissues with molecular resolution. Existing methods are either limited spectrally to 3-4 targets, as is the case of conventional fluorescence in situ hybridization and immunohistochemistry, or limited by complex ...

    SBIR Phase I 2021 Department of Health and Human ServicesNational Institutes of Health
  9. Topic 345: RadTox- Measuring Radiation Toxicity using Circulating DNA

    SBC: DiaCarta, Inc.            Topic: NCI

    The QuantiDNA RadTox System is a unique, patented technology that measures tissue damage shortly following injury using cell-free DNA from a drop of blood. Premised on murine and primate studies showing circulating DNA is logarithmically increased with whole-body radiation dose, RadTox has the potential to overcome many of the species-specific challenges faced by biomarker panels. The phase I SBIR ...

    SBIR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health
  10. TOPIC #355- SBIR PHASE II- A 3D PERFUSABLE PLATFORM FOR HTS ACROSS DIVERSE RACIAL/ETHNIC CANCER SPE

    SBC: MIMETAS US, INC            Topic: NCI

    Prostate cancerPCaincidence and mortality in African American men is two times greater than men of other races ethnicities in the United StatesElucidating the underlying mechanisms for this cancer health disparityCHDis critical to patient treatment and improved patient outcomehowever there are no in vitro models available to adequately recapitulate the PCa tumor microenvironment across races ethni ...

    SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
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