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The Award database is continually updated throughout the year. As a result, data for FY23 is not expected to be complete until September, 2024.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

Displaying 196101 - 196110 of 205043 results
  1. Ultrasensitive Approaches for Complex Animal Proteomics

    SBC: CALIBRANT BIOSYSTEMS, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Biologically and clinically relevant proteomic data can only be generated if organ or tissue samples investigated consist of homogeneous cell populations, in which no unwanted cells of different types and/or development stages obscure the results. One of the main problems with the analysis of tissue samples is the heterogeneous nature of the sample. Many differ ...

    SBIR Phase II 2009 Department of Health and Human ServicesNational Institutes of Health
  2. Plant-Derived hepatitis B Vaccine from Biomanufacturing System to Clinical Trial

    SBC: QUANTUM TUBERS CORPORATION            Topic: N/A

    DESCRIPTION (provided by applicant): The ability of plants to be used as factories for the production of biopharmaceuticals has the potential to dramatically cut costs of production of many current biotherapeutics and will encourage development of new drug s and vaccines that can be genetically inserted into the genome of certain plants. Production via plants by growing biomass from plants that ar ...

    SBIR Phase II 2008 Department of Health and Human ServicesNational Institutes of Health
  3. System for Ocular Oxygen Measurements

    SBC: Ocumetrics Inc            Topic: NEI

    DESCRIPTION (provided by applicant): The purpose of this project is to develop systems for measuring oxygen concentrations on and inside the eye. These systems will take advantage of phosphorescent probes that are sensitive to oxygen concentrations. They will have obvious applications in eye research and will lead to advancements in our understanding of ocular diseases, development of new drugs, c ...

    SBIR Phase II 2010 Department of Health and Human ServicesNational Institutes of Health
  4. Development of a Neonatal Abstinence Syndrome Therapy

    SBC: Mu Therapeutics Inc.            Topic: NIDA

    Neonatal Abstinence Syndrome (NAS) has skyrocketed in recent years as a result of the opioid epidemic plaguing this country. Since 2000, the number of babies affected by NAS has increased nearly 5-fold. Every 25 minutes a baby is born suffering from opioid withdrawal, often prematurely with developmental problems and potential long-term adverse effects including cognitive impairment. Approximately ...

    SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  5. Kiddio: Food Fight- Training Vegetable Parenting Practices

    SBC: Archimage, Inc.            Topic: N

    DESCRIPTION provided by applicant Higher vegetable intake has been related to lower risks of diabetes cardiovascular disease several cancers and obesity adiposity later in life Yet children are eating vegetables well below recommended amounts Parents are important influencers on the dietary intake of young children but they commonly report difficulty getting their child to eat vegetables ...

    SBIR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health
  6. Tl-Halide Scintillators for TOF-PET

    SBC: RADIATION MONITORING DEVICES, INC.            Topic: NIBIB

    Project SummaryThe current detector technology in PET requires scintillation that has fast response, excellent timing resolution, high detection sensitivity, good energy resolution, and last but not least acceptable cost. At present, most PET systems use crystals of LSO (Lu2SiO5:Ce) or its analog LYSO, which satisfy many of the listed requirements. But LSO, after years of development, has reached ...

    SBIR Phase II 2022 Department of Health and Human ServicesNational Institutes of Health
  7. Safety of A2A Adenosine Agonist for Treatment of Sepsis

    SBC: ADENOSINE THERAPEUTICS, LLC            Topic: N/A

    DESCRIPTION (provided by applicant): ATL146e is a synthetic small molecule developed by Adenosine Therapeutics, LLC (ATL) that acts as a selective agonist of the adenosine A2A receptor. ATL146e, sterile solution for intravenous (i.v.) bolus injection, is currently in Phase III of clinical development for use as a coronary vasodilator in pharmacodynamic stress imaging. ATL146e, when administered pa ...

    SBIR Phase I 2006 Department of Health and Human ServicesNational Institutes of Health
  8. Safety of A2A Adenosine Agonist for Treatment of Sepsis

    SBC: ADENOSINE THERAPEUTICS, LLC            Topic: N/A

    DESCRIPTION (provided by applicant): ATL146e is a synthetic small molecule developed by Adenosine Therapeutics, LLC (ATL) that acts as a selective agonist of the adenosine A2A receptor. ATL146e, sterile solution for intravenous (i.v.) bolus injection, is currently in Phase III of clinical development for use as a coronary vasodilator in pharmacodynamic stress imaging. ATL146e, when administered pa ...

    STTR Phase I 2006 Department of Health and Human ServicesNational Institutes of Health
  9. Novel recombinant sensors to study histone ubiquitin signaling

    SBC: Epicypher, Inc.            Topic: 400

    PROJECT SUMMARYMonoubiquitination (Ub) of histones is an important post-translational modification (PTM) that regulates multiple DNA-related processes including DNA replication, transcription, and repair. Aberrant regulation of histone Ub is strongly linked to the pathogenesis of diverse diseases, including cancer, aging, and inflammation. However, the ability to map the distribution and dynamics ...

    SBIR Phase II 2023 Department of Health and Human ServicesNational Institutes of Health
  10. Software for Determination of Macromolecular Structures

    SBC: QEDLabs            Topic: N/A

    DESCRIPTION (provided by applicant): Macromolecular structure determination using electron microscopy has become a useful research tool aimed at understanding biological processes, identifying conformational changes, and characterizing components in cellular pathways. Our long-term goal is to broaden the group of people able to determine macromolecular structures by providing integrated, easy t ...

    SBIR Phase II 2003 Department of Health and Human ServicesNational Institutes of Health
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