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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

Displaying 196151 - 196160 of 207725 results
  1. Sea and Observe: Littoral Foundations of Structured Understanding and Iterative Discovery for Image Detection, Identification and Annotation

    SBC: EH GROUP INC            Topic: NGA203005

    This proposal addresses the algorithm research and development of structure and iterative discovery for image detection, identification, annotation, and understanding. Our approach is inspired from the ability of humans to encapsulate and develop mental models and the ability of AI to algorithmically learn and contribute to the identification of features, textures, and salient and camouflaged char ...

    SBIR Phase I 2022 Department of DefenseNational Geospatial-Intelligence Agency
  2. Non-Contact Solution for Quantitative Clinical Management of MTD

    SBC: ALTEC, INC            Topic: NIDCD

    This Phase I SBIR will develop a new clinical software that can be used by Speech Language Pathologists (SLPs) to inform the assessment and treatment of Muscle Tension Dysphonia (MTD), one of the most common voice disorders in clinical practice. MTD is characterized by abnormal coactivation of muscles in and around the larynx that causes vocal strain - leading to discomfort and pain that impede vo ...

    SBIR Phase I 2022 Department of Health and Human ServicesNational Institutes of Health
  3. Development of a protein drug for pancreatic cancer treatment

    SBC: ProDa BioTech L.L.C.            Topic: 102

    Abstract Pancreatic cancers are devastating diseases with five year survival rate less than 9%. Currently, there is no effective treatment for advanced disease. One major barrier to efficacy of anti-tumor therapeutics is the dense desmoplastic stromal response. Evidence suggests that cancer associated pancreatic stellate cells (CaPSC) produce the stromal collagen. The ECM laid down by CaPSC is con ...

    SBIR Phase II 2022 Department of Health and Human ServicesNational Institutes of Health
  4. Deep learning augmented protein mapping software to screen large compound libraries

    SBC: ACPHARIS            Topic: 400

    Fragment based drug discovery starts with screening libraries of fragment-sized organic molecules for binding to the target protein. The fragments cluster at binding hot spots, the most important regions for drug discovery, and can be extended into larger and higher affinity ligands. The protein-mapping program FTMap is a computational analogue of fragment screening experiments. Acpharis has licen ...

    SBIR Phase I 2022 Department of Health and Human ServicesNational Institutes of Health
  5. Ultra-Sensitive Vapor Phase Hydrogen Peroxide Sensor for Decontaminating Pharmaceutical Manufacturing Facilities

    SBC: PHYSICAL SCIENCES INC.            Topic: 400

    Project Summary/AbstractPhysical Sciences Inc. (PSI) is developing a sensor that can accurately measure ppbv to ~1000 ppmv concentrations of vapor phase hydrogen peroxide (VPHP). This sensor will be used for inline monitoring of VPHP concentrations of barrier isolators used for fill/finish operations of parenteral drugs. The capability to accurately and sensitively monitor VPHP is critical, as res ...

    SBIR Phase II 2022 Department of Health and Human ServicesNational Institutes of Health
  6. Automating Systematic Reviews of Environmental Health Literature with Machine Learning

    SBC: IDOC SOFTWARE INC            Topic: R

    Project Summary IDOC Software proposes the development of Artificial Intelligence (AI) algorithms, together with user-friendly software, for facilitating the efficient production of Systematic Reviews (SRs) in the field of Environmental Health (EH). SR is the “Gold Standard” for assessing evidence to be used for decision making in a variety of health contexts, including health care, public hea ...

    SBIR Phase I 2022 Department of Health and Human ServicesNational Institutes of Health
  7. Civamide Nasal Spray for the Treatment of Dry Eye

    SBC: ELORAC, INC.            Topic: NEI

    7. Project Summary/Abstract The project is a Phase II clinical study of Civamide Nasal Spray for the treatment of Dry Eye Disease, an irritating and potentially severely disabling ocular disease. If this study is successful in the treatment of Dry Eye Disease, further clinical development will proceed, i.e., Phase 3 studies to support the filing of a New Drug Application. Currently, all approved m ...

    SBIR Phase I 2022 Department of Health and Human ServicesNational Institutes of Health
  8. LentiTag: A novel approach to the efficient manufacturing of active lentiviral vectors

    SBC: ISOLERE BIO INC            Topic: 400

    PROJECT SUMMARY Cell and gene therapies are garnering attention for their remarkable clinical outcomes and their promise to treat diseases previously considered uncurable. Lentiviral vectors (LVs) are used in over one third of applications in cell and gene therapies.2 As with most viral vector and vaccine manufacturing, LVs are challenging and expensive to manufacture and there are no methods in c ...

    SBIR Phase I 2022 Department of Health and Human ServicesNational Institutes of Health
  9. Technology Assisted Treatment for Trichotillomania

    SBC: HABITAWARE, INC.            Topic: 102

    Abstract Significance: Trichotillomania (TTM), characterized by repeated pulling of one’s hair to the point of hair loss or thinning, produces impairment in physical, social, psychological and occupational functioning. While evidenced-based treatments (EBTs, i.e. self-monitoring, stimulus control, and Habit Reversal Training (HRT)) do exist, access is limited due to lack of trained treatment pro ...

    SBIR Phase II 2022 Department of Health and Human ServicesNational Institutes of Health
  10. Improving influenza vaccines through wastewater-based macro-scale strain surveillance

    SBC: GT MOLECULAR, INC.            Topic: NIAID

    ABSTRACT Influenza infects 9 to 45 million people in the United States each year and results in 300,000 to 500,000 deaths worldwide. Vaccination is the foundation of the global response to control and reduce the spread of Influenza; however, seasonal influenza vaccine efficacy ranged from non-statistically significant to 60% between 2011 and 2019.Vaccine efficacy is largely contingent upon properl ...

    SBIR Phase I 2022 Department of Health and Human ServicesNational Institutes of Health
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