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Description (from the investigator's abstract): The objective of this application is to implement an iterative, nine-step advanced vision intervention algorithm (AVIA) in software to optimize the predictability of virtually any current or anticipated customized human vision intervention method. The software program will use the investigator's Vis ...

Objectives: Design, develop, validate and market a low-cost, easy-to-use subjective refractor unit to quickly and accurately measure a patient's required vision correction in terms of sphere, cylinder and axis. Specific Aims: Establish the scientific merit and feasibility of the subjective efraction by meridional power matching technique by 1) designing an off-the-shelf SR-MPM using ZEMAX; 2) c ...

DESCRIPTION (provided by applicant): Objective: Develop a new reflection-based corneal topographer that provides more reliable and accurate measurements of the anterior corneal surface than those of commercially available systems. Specific Aims: Determine the feasibility of the multi-resolution corneal topograher (MRCT) by: (1) developing prototype color multiple-resolution reflection target ...

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DESCRIPTION (provided by applicant): 1. Project summary: The broad, long-term objective is to develop a Scanning ocular Aberration Measurement (SAM) system that solves five shortcomings of current wavefront sensors. Most or all current systems: 1) are too expensive for deep market penetration, 2) do not monitor the pupil size and location as a function of illumination and accommodation, 3) are no ...

DESCRIPTION (provided by applicant): Objective: Develop a Scanning ocular Aberration Measurement (SAM) system that solves five problems of current wavefront sensors. Current systems do not: 1) measure aberrations during accommodation; 2) allow variable density sampling depending on the severity of the ocular aberration; 3) monitor pupil size and location as a function of ambient illumination and a ...

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Marous, James R. An Eye Bank Endothelial Cell Counter Abstract Procurement of donor corneal tissue for transplant use is an important social service undertaken by largely underfunded eye banks. Tissue is not only harvested, but must be screened for a myriad of issues that may make the tissue unsuitable for transplant or pose a health risk to the tissue recipient. Donor tissue may be rejected for ...

This Small Business Innovative Research Phase I research develops technologies to address the increased demands on both families of and institutions serving patients with cognitive and physical impairments to monitor and track patients. Wandering is a common problem in people with dementia. This research expands exisiting system technology to provide monitoring and tracking that covers an area ove ...