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Retaining polar lipid head group identity by linking drugs to acyl chains to increase drug targeting would represent a significant accomplishment. The ability to direct material to specific locations reduces the need to saturate all pharmacological compartments to achieve therapeutic levels in one. The Phase I research proposed will determine the feasibility of delivering pharmaceutical agents li ...

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CHEIMICAL/BIOLOGICAL CONTAIMINATION OF A DEEP BASE PRESENTS A SIGNIFICANT, POSSIBLY SYSTEMS NEGATING, NON-NUCLEAR THREAT. MICROWAVE INDUCED IONIZATION OF CHEMICAL WARFARE AGENTS WILL ENABLE THE USE OF NON-TOXIC DECONTAMINATING AGENTS. MICROWAVE IONIZATION IS RELATED TO IR SPECTROPHOTOMETRY, A TECHNOLOGY WIDELY USED IN INDUSTRY. IF MICROWAVES ARE PROVEN TO CAUSE THE TRANSITION OF ELECTRONS IN ORGAN ...

Drug diversion, defined as “the transfer of a controlled substance from a lawful to an unlawful channel of distribution or use,” is a challenging issue in todayandapos;s healthcare systems. Based on an analysis, the volume of dosage lost due to diversion increased from 21 million in 2017 to 47 million in 2018, a 126% increase. This resulted in over $450M loss to healthcare systems due to drug ...

The Navy requires an architecture for acquiring and storing 3-Dimensional obstacle data. An extension of the Terrain Awareness Warning System (eTAWS), the obstacle database must store man-made objects such as buildings, bridges, towers, overpasses, and wires. The system must be able to generate obstacle database data from a number of sources including synthetic aperture radar (SAR), stereo/multi ...

The introduction of substandard or counterfeit materials into the DoD supply chain can have extremely expensive, and potentially life threatening, consequences. Current techniques used to detect nonconforming materiel can be destructive (e.g., manual sectioning and inspection of a part), time consuming and expensive (e.g., micro-computed tomography, ultrasound), or provide only limited informatio ...

Technology in Blacksburg, Inc., is proposing to use Micro-Electro-Mechanical-Systems (MEMS) to reduce boundary-layer losses in the stators of highly-loaded transonic compressor stages. MEMS-based micropumps will bleed-off the low velocity fluid on the blade suction surface resulting from the boundary layer separation. The work added by the micropump to this low momentum fluid will re-energize th ...

Project Summary andquot Using Meta level Smartphone Data to Promote Early Intervention in Schizophrenia Schizophrenia is one of the most debilitating disorders in the world today It affects over million adult Americans each year NIMH director Dr Thomas Insel has declared The best chance for preventing serious functional disability among people with schizophrenia may be to intervene at th ...

THIS PROJECT WILL EXPLORE NEW METHODS OF FABRICATING THE RECENTLY REPORTED CONDUCTIVE POLYMER, POLY (ISOTHIANAPHTHENE) (PITN). WHEN ELECTROCHEMICALLY FORMED FILMS OF PITN ARE DOPED, THEY HAVE A HIGH CONDUCTIVITY AND ARE HIGHLY TRANSPARENT IN THE VISIBLE PORTION OF THE SPECTRUM. BECAUSE THE POLYMER FILM CAN BE PRODUCED AT LOW TEMPERATURES, IT OFFERS AN ALTER- NATIVE TO THE PRESENTLY USED WIDE-BANDG ...