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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

Displaying 196161 - 196170 of 207699 results
  1. Robot-assisted prostate surgery using augmented reality with deformable models

    SBC: KITWARE INC            Topic: NIBIB

    DESCRIPTION (provided by applicant): In this application, we describe our proposed work to develop an augmented display for improved visualization of the prostate and surrounding critical anatomy for robot-assisted prostate surgery. Prostate cancer is the second leading cause of cancer-related deaths in men in the United States. It is estimated that 217,730 men will be diagnosed with and 32,050 ...

    SBIR Phase I 2011 Department of Health and Human ServicesNational Institutes of Health
  2. Decision Support System for Predicting outcome of ER+ breast cancers

    SBC: IBRIS, INC.            Topic: NIBIB

    DESCRIPTION (provided by applicant): We propose an alternative, inexpensive means for identifying the subset of women with ER+ breast cancer for whom hormonal therapy alone is sufficient, and adjuvant chemotherapy is not required. Our novel approach uses computer vision and machine learning techniques to extract information from digitized histological sections of breast tissue (e.g. graphical and ...

    SBIR Phase I 2011 Department of Health and Human ServicesNational Institutes of Health
  3. MULTI-ANALYTE IMMUNOCHROMATOGRAPHIC TEST STRIP FOR BACTERIAL TOXIN DETECTION

    SBC: INNOSENSE CORPORATION            Topic: NIEHS

    DESCRIPTION (provided by applicant): Many different disease-causing microbes, or pathogens, can contaminate foods, so there are many different foodborne infections. Harmful toxins or chemicals can also contaminate food, for example, poisonous mushrooms. The microbes or toxins enter the body through the gastrointestinal tract, and often cause the first symptoms. Nausea, vomiting, abdominal cramps a ...

    SBIR Phase I 2011 Department of Health and Human ServicesNational Institutes of Health
  4. Novel Use of Confocal Microscopy on Cultured Porcine Corneas for Pre-Clinical Tes

    SBC: MB RESEARCH LABORATORIES, INC.            Topic: NIEHS

    DESCRIPTION (provided by applicant): There is an important need for screening methods that can detect and distinguish the relative eye discomfort or sting potential of cosmetic, personal care, or pharmaceutical formulations early in their developmental stages. The only currently reliable method available is costly and sometimes painful human clinical eye testing, in which test substances are int ...

    SBIR Phase I 2011 Department of Health and Human ServicesNational Institutes of Health
  5. E-Learning Assisted HAZWOPER Training for Coroners and Medical Examiners

    SBC: D&E TECHNICAL, INC            Topic: NIEHS

    DESCRIPTION (provided by applicant): Human death investigations must by law be properly implemented even when the decedent is involved in or near to the scene of a hazardous materials emergency. This project intends to develop worker health and safety training for those staff of coroners and medical examiners who investigate deaths in hazardous materials environments. This innovative training will ...

    SBIR Phase I 2011 Department of Health and Human ServicesNational Institutes of Health
  6. Advanced GST Proteomics for Early Stage Organ-Specific Toxicity Screening

    SBC: OXFORD BIOMEDICAL RESEARCH, INC.            Topic: NIEHS

    DESCRIPTION (provided by applicant): Current biomarkers employed in the detection of organ toxicity are often not sensitive enough to detect the early stages of acute organ damage, i.e. at a stage when reducing or eliminating exposure to a toxin could prevent progression of organ damage or a disease process. By the time current toxicity biomarkers are detected in biological fluids there is already ...

    SBIR Phase I 2011 Department of Health and Human ServicesNational Institutes of Health
  7. Allergens and Induced Asthma: Eradicating Indoor Allergens and Dust Mites

    SBC: CarboNix LLC            Topic: NIEHS

    DESCRIPTION (provided by applicant): Allergens and Induced Asthma: Eradicating Indoor Allergens and Dust Mites The mission of CarboNix LLC is the clinically effective abatement of common indoor allergens that cause allergic reactions and frequently induceasthma, especially in children. The focus of this project is on the dust mite. Carbonix LLC proposes a Phase I research program, leading to a com ...

    SBIR Phase I 2011 Department of Health and Human ServicesNational Institutes of Health
  8. NOVEL HIGH THROUGHPUT PLATFORM FOR SCREENING CYTOCHROME P450 INDUCTION

    SBC: ORIGINUS, INC.            Topic: NIEHS

    DESCRIPTION (provided by applicant): Metabolism of administered drugs is determined by expression and activity of drug-metabolizing enzymes, such as cytochrome (CYP) P450 enzymes. These P450s are subject to inhibition and sometimes induction by xenobiotics, leading to possible pharmacokinetic drug-drug interactions between co-administrated drugs. Recognizing the problem, the FDA has issued a Draft ...

    SBIR Phase I 2011 Department of Health and Human ServicesNational Institutes of Health
  9. Novel Organophosphate Biosensor

    SBC: Inscent, Inc            Topic: NIEHS

    DESCRIPTION (provided by applicant): The long-term objective of this project is the development of a rapid and low cost detection tool, based on novel biosensor receptor elements, to test human urine for organophosphate pesticide exposure - a global publichealth issue. Chronic low dose exposure can result in a variety of neuropathies, increased incidence of leukemia, birth defects and learning dis ...

    SBIR Phase I 2011 Department of Health and Human ServicesNational Institutes of Health
  10. Model of the Human Testis for Reproductive Toxicology

    SBC: MANDALMED, INC.            Topic: NIEHS

    DESCRIPTION (provided by applicant): More than 87,000 chemicals have been developed and distributed over the past 50 years. The vast majority of these have not been tested for potential toxic effects in humans or animals. Most systematic toxicology research is conducted in animals and is very expensive. Although animal studies contribute important information, they may not closely approximate the ...

    SBIR Phase I 2011 Department of Health and Human ServicesNational Institutes of Health
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