Award Data

The MDA is developing the Precision Tracking Space System and other satellite based systems that could benefit from ongoing developments in advanced materials for lithium ion batteries. Unfortunately, the applications driving much of that battery research have less abusive operational cycles than the frequent cycling, and sporadic pulse loads to deep discharge, of MDA satellite applications. Phy ...

ABSTRACT: Our objective is to develop advanced mediator architectures for efficient electron transfer in enzymatic fuel cells (EFCs) for low power systems. The proposed EFC will leverage ongoing research at both CFDRC and Michigan State University to provide a fully-integrated lightweight, low-cost, manufacturable, and renewable power supply, for various military and civilian applications. EFC sy ...

The overall goal of the proposed effort is to develop and demonstrate rigorous model order reduction (MOR) technologies to automatically generate fully coupled, nonlinear, parameterized aeroservoelastic reduced-order models (ROMs) for smart material-based active structural control. The Phase I effort will focus on developing constituent nonlinear ROMs for aerodynamics, structural dynamics, and ele ...

Scramjet engines promise to become a next-generation revolutionary technology for aerospace applications. Some of the significant challenges in rapid development of scramjets include complex flow physics; combustion; flow-combustion interactions; propulsion air-frame integration; coupled with difficulty in producing realistic experimental conditions. The role of Computational Fluid Dynamics (CFD) ...

The goal of this SBIR project is to advance the state-of-the-art in computations of hypersonic plasmas by adding high-fidelity kinetic models for electrons. Electron kinetics affects plasma-chemical reactions and nonequilibrium radiation, which are important for designing hypersonic vehicles. We will develop adaptive multi-scale models for electrons applicable for hypersonic flows in rarefied and ...

DESCRIPTION (provided by applicant): We propose to develop and demonstrate a novel microfluidic device and assay for selection and optimization of delivery vehicles, specifically non-viral vectors for drug delivery to tumors. Tumor drug delivery is a complex phenomenon affected by several elements in addition to drug or delivery vehicle's physico-chemical properties. A key factor is tumor mic ...

DESCRIPTION (provided by applicant): The overall objective of this study is to develop a novel in vitro microfluidic platform to test a drug or delivery vehicle's ability to permeate the Blood-Brain Barrier (BBB). In contrast to current in-vitro models, our proposed device, SIM-BBB, comprises of a microfluidic two-compartment chamber. The chamber is designed in such a way as to permit vis ...

Rapid and accurate characterization and/or identification of the differentiation state of the stem cells is critical to the development of regenerative medicine technologies as well as tissue engineering solutions. Current methods and devices are time-consuming, labor-intensive, costly, invasive, and consequently, ill-suited for deployment in military and other limited resource settings. To overco ...

ABSTRACT: Operating in a Service-Oriented Architecture (SOA) environment is risky because there is limited ability to gauge information"s trust level. Existing solutions track information pedigree, but do not consider other prerequisites to trust. This project proposes to build METSI (Metadata Establishing Trust in SOA-based Information) to quantify trust using six Quality of Information (QoI) me ...

ABSTRACT: Our objective is to develop an enzyme catalyzed fuel cell to enable electrochemical power generation from several fuel types (i.e. sugars and alcohols), thereby delivering a state-of-the-art energy source for low power military and commercial systems. The proposed enzymatic fuel cell (EFC) will leverage ongoing research at both CFDRC and the University of New Mexico to provide a fully- ...