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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

Displaying 196171 - 196180 of 207731 results
  1. A Rapid Point-of-care Diagnostic for Neisseria gonorrhoeae STDs

    SBC: NetBio, Inc.            Topic: NIAID

    DESCRIPTION (provided by applicant): Improved diagnosis of Neisseria gonorrhoeae (GC) infections represents a critical unmet medical need. The CDC estimates that approximately 700,000 people are infected by GC annually, with approximately half of these cases reported. The clinical spectrum of GC infection includes urethritis and cervicitis, pelvic inflammatory disease (PID), and disseminated disea ...

    SBIR Phase I 2011 Department of Health and Human ServicesNational Institutes of Health
  2. Human Ghrelin As An Effective Mitigator of Acute Radiation Injury

    SBC: THERASOURCE, LLC            Topic: NIAID

    DESCRIPTION (provided by applicant): This SBIR Phase I proposal is intended to demonstrate the feasibility of developing a novel and effective therapeutic approach that can save lives of people with radiation injury. Acute radiation injury may occur in various incidents as well as the terrorist radiation exposure scenario. Acute radiation syndrome develops after whole-body or a partial-body irradi ...

    SBIR Phase I 2011 Department of Health and Human ServicesNational Institutes of Health
  3. Identification of novel influenza antivirals

    SBC: ARISAN THERAPEUTICS INC            Topic: NIAID

    DESCRIPTION (provided by applicant): The influenza A virus represents one of the greatest global human health risks. Although vaccines provide significant protection from seasonal flu infections they still account for an estimated 36,000 deaths and 200,000hospitalizations per year in the US alone. Furthermore, the inherent time involved in development, production and distribution of vaccines limit ...

    SBIR Phase I 2011 Department of Health and Human ServicesNational Institutes of Health
  4. Rapid screening tool for antibiotic resistant pathogens

    SBC: Resonant Sensors Incorporated            Topic: NIAID

    DESCRIPTION (provided by applicant): The innovation presented in this proposal is a new class of label-free biochemical sensors with applicability in point of care (POC) medical diagnostics. The goal of the project to develop commercial biochip systems with compelling performance metrics targeted for rapid screening of an array of antibiotic resistant microbials in a clinical setting. The biochips ...

    SBIR Phase I 2011 Department of Health and Human ServicesNational Institutes of Health
  5. A Combination Therapy Approach to Treating Drug Resistant Fungal Infections

    SBC: Amplyx Pharmaceuticals, Inc.            Topic: NIAID

    DESCRIPTION (provided by applicant): There is an urgent need to discover more effective therapeutic regimens for fungal infections. Nosocomial infections caused by Candida albicans have a 50% mortality rate. Aspergillosis is a leading cause of death in organ transplant recipients, as well as patients suffering from cancer and auto-immune disorders. The annual cost of treating fungal infections is ...

    SBIR Phase I 2011 Department of Health and Human ServicesNational Institutes of Health
  6. Novel Antibacterial Scaffold from Natural Products

    SBC: LIFEPHARMS, INC.            Topic: NIAID

    DESCRIPTION (provided by applicant): Despite the rise of bacterial resistance to antibiotics, the development of new antibiotics is on the decline. Methicillin-resistant Staphococcal aureus infections (MRSA) in the United States has been increasing, causing 19,000 deaths per year in the United States and contributing to 3 billion to 4 billion of additional annual health care costs. The issue of ...

    SBIR Phase I 2011 Department of Health and Human ServicesNational Institutes of Health
  7. Origami MALE CONDOM-3: Feasibility and Acceptability Study, Phase 1 Clinical Resear

    SBC: Strata Various Product Design            Topic: NIAID

    DESCRIPTION (provided by applicant): The primary objective of this project is to build on prior Phase 1 research to improve product sensitivity properties, to refine and test modifications of the Origami Male Condom 1 (OMC 1), and develop a more consumer-acceptable device exclusively for vaginal-penile intercourse, the Origami Male Condom 3 (OMC 3). Made of custom formulated biocompatible, viral-i ...

    SBIR Phase I 2011 Department of Health and Human ServicesNational Institutes of Health
  8. High-throughput Epitope Mapping of Anti-Viral Antibodies

    SBC: INTEGRAL MOLECULAR INC            Topic: NIAID

    DESCRIPTION (provided by applicant): The identification of highly potent and broadly neutralizing antibodies isolated from HIV-1- infected donors suggests that when presented with a suitable antigenic structure, the human immune system can produce protective antibodies that HIV-1 is unable to evade. Understanding these antigenic structures is a primary objective in developing a vaccine capable of ...

    SBIR Phase I 2011 Department of Health and Human ServicesNational Institutes of Health
  9. SAMBA HIV-1 Semi-quantitative Test for resource limited settings

    SBC: DIAGNOSTICS FOR THE REAL WORLD LIMITED            Topic: NIAID

    DESCRIPTION (provided by applicant): The ultimate aim of this project is to develop a CE-marked and/or FDA-approved diagnostic platform for viral load monitoring of HIV-1 infected patients in point-of-care (POC) and resource- limited settings. Currently available viral load tests are not suitable for such settings due to their inherent high cost, complexity and size, thus patients, especially in t ...

    SBIR Phase I 2011 Department of Health and Human ServicesNational Institutes of Health
  10. Multi-view, Photon Counting DXA Scanner for Quantitative Musculoskeletal Imaging

    SBC: QUANTUM MEDICAL METRICS, LLC            Topic: NIAMS

    DESCRIPTION (provided by applicant): The fragility of osteoporotic bones is largely due to alterations in the underlying structural geometry. Research has demonstrated that it is possible to measure the mechanical geometry of human bones in vivo using dualenergy x-ray absorptiometry (DXA) scans. However DXA scanners are designed to measure bone mineral density (BMD) and not structural geometry. Th ...

    SBIR Phase I 2011 Department of Health and Human ServicesNational Institutes of Health
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