Award Data

Binge Eating Disorder (BED) is the most common eating disorder and carries an elevated risk of medical complications due to uncontrolled overeating. It can be treated effectively with stimulants, but their known abuse and diversion risk is a persistent concern. Our strategic approach is to build on the proven efficacy of stimulants in BED while reducing abuse potential. The goal of this Fast-Track ...

Project Summary Abstract PreDxion BioLLC is a precision medicine diagnostic company developing an assay platformthe MicroKineassay cartridge and readerthat measures serum proteins in less thanminutes from a single drop of bloodThis fastactionable information allows for the first time individualized precision medicine aimed at reducing pediatric morbidity and mortality in pediatric sepsisthe number ...

Ultra-Scan will leverage the company's previously developed multimodal fusion technology to quantify the accuracy and validate the performance of its Neyman-Pearson fusion software for use with mission critical tactical identification systems, verifying that a score level fusion matching capability is achievable. A platform independent interface will be developed to allow integration of Ultra ...

SEVERAL STATES ARE CURRENTLY SEEKING MUCH-NEEDED NEW LOW-LEVEL RADIOACTIVE DISPOSAL SITES IN ACCORDANCE WITH THE LOW-LEVEL RADIOACTIVE WASTE POLICY ACT OF 1980. ANY NEW COMMERCIALREQUIREMENT THAT A SITE BE CAPABLE OF BEING MODELED AND THATITS PERFORMANCE BE ASSURED FOR 500 YEARS. FOR MOST SITES, THE HYDROGEOLOGICAL AND RADIONUCLIDE TRANSPORT CHARACTERIS- TICS OF THE UNSATURATED ZONE ARE MAJOR FACT ...

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DESCRIPTION (provided by applicant): The objective of this research is to commercialize a device (the Oncoscope Panocyte system) used to guide biopsy selection in patients with Barrett's esophagus (BE) during standard endoscopy surveillance for early- stage esophageal cancer. Barrett's esophagus most often develops in patients with chronic acid reflux and is the strongest risk factor fo ...

DESCRIPTION provided by applicant The founders of Skeletal Tissue Engineering Laboratory Technologies LLC STEL are researchers at the University of Michigan Our research team has developed an innovative and paradigm shifting approach to ligament tissue engineering and a unique methodology for ACL replacement This tissue engineered ligament technology offers the possibility of radical impr ...

DESCRIPTION (provided by applicant): Age-related macular degeneration (AMD) is the most common cause of visual impairment of the elderly in developed countries. Despite its prevalence with the aging population, its etiology and pathogenesis are poorly understood and the treatment options are limited. CalCyte's scientific co-founder, Kang Zhang, reported that polymorphisms in the promoter of the ge ...

ABSTRACT Sepsis, a systemic inflammatory condition, occurs as a complication of infection and in severe cases may be associated with acute and life-threatening organ dysfunction. In the US alone, sepsis claims ~270,000 lives each year among ~1.7 million patients diagnosed annually, and globally, sepsis-related mortality is estimated to account for 20% of total deaths. Although improvements in the ...

different modes, while using different combinations of subsystems. This presents a challenge for the personnel validating the system during design and development; the number of combinations of environments, modes, and subsystems is exponential. They cannot all be tested, so an optimal subset of tests must be run. We propose to develop VERITAS: Validation and Evaluation of Remote, Interactive Tea ...