Award Data

DESCRIPTION (provided by applicant): This proposal is written in response to NIMH topic "F. Genetic and Transgenic Technology (subtopic 7): "Innovative technologies to study gene function and expression" listed in the 2001 Omnibus Solicitation for SBIR/STTR grants. The commercial objective of MusWorks Inc. is to provide a mouse aggregation chimera production service to the biomedical research com ...

The commercial objective of MusWorks Inc. is to provide a mouse aggregation chimera production service to the biomedical research community. Mouse chimeras are genetically composite animals whose cells are derived from different embryos. Chimera analysis

The development of new herbicides continues to be an important agricultural concern in the U.S., where hundreds of millions of pounds of plant pesticides are used annually. The search for new agents that have low toxicities to non-target organisms (especially humans) requires the identification and exploitation of biochemical differences between plants and other higher eukaryotes. The enzyme methy ...

The practice of medicine is confounded by severe restrictions as the Human Race reaches farther out into space. A Mars mission will have communication delays of up to 40 minutes and make emergency support difficult. Intelligent medical systems will have to be devised to support these efforts. Current technologies have developed to where a combination of different artificial intelligent methodologi ...

Mycotech produces Mycotrol, a commercial preparation of Beauveria bassiana (Bb). The residuecontains 109 spores of Bb per gram which could be economically used to reduce European corn borer(ECB) damage to corn crops. The objective is to develop an economic bio-control strategy for ECB.Three strategies for applying the Mycotrol residue to corn are proposed:¿ inoculating the seed and/or soil duri ...

DESCRIPTION (provided by applicant): In order to reduce escalating health care costs, rapid "point-of-care" (POC) testing has dramatically grown over the last decade. Due to their relative ease, immunologic approaches are frequently used for such tes

THE APPLICATION OF NEURAL NETWORK TECHNIQUES TO PREDICTING PERSONNEL ATTRITION CAN HAVE SEVERAL ADVANTAGES OVER CONVENTIONAL APPROACHES SUCH AS TIME SERIES METHODS AND ECONOMETRIC MODELS. THE POWER OF THE NEURAL NETWORK APPROACH HAS BEEN DEMONSTRATED BY THEIR ABILITY TO REPRESENT NONLINEAR MAPPING NETWORKS, AND TO SUCCESSFULLY MANAGE MULTIVARIATE DATA. THIS PHASE I PROGRAM WILL IDENTIFY AND CHARAC ...

MILITARY LOSS FORECASTING IS AN IMPORTANT PROBLEM FOR SEVERAL REASONS. PERSONNEL LOSSES ARE COSTLY BECAUSE THEY INCREASE THE NUMBER OF PEOPLE WHO MUST BE RECRUITED AND TRAINED. MORE SERIOUS IS THE PROSPECT OF MILITARY MISSIONS DEGRADED BY MANPOWER SHORTAGES. THERE ARE SEVERAL DIFFERENT TYPES OF FORECASTING METHODOLOGIES IN USE AT THE PRESENT TIME. FOR EXAMPLE ORDINARY LEAST SQURES STEPWISE REGRESS ...

The current methods for estimating stroke volume rely on respiratory gas analysis, bioimpedance, echocardiography, and catheter-based techniques and are impractical for the battlefield environment. Research into the medical use of Ultra-WideBand (UWB) has shown it is capable of non-invasive collection of a variety of medically significant data and holds promise as a means of estimating cardiac str ...

LifeWave is completing work on the Phase I SBIR “Use of Non-Invasive Methods to Determine Stroke Volume”. Completed efforts to date include FDTD computer simulations of the UWB radar and human torso and algorithms for stroke volume measurement using cardiac phantom data. Results of these efforts show that it is theoretically possible to measure stroke volume with UWB radar. The objective of th ...