Award Data

Quantitative estimation of blood loss in wounded battlefield casualties must be promptly transmitted to medics for corrective actions. Yet heart rate and blood pressure measures are often inadequate, and the more accurate invasive measures of stroke volume as well as derived measures from the ventricular volume curve (obtained with echo-Doppler) cannot be employed logistically. Real-time, battle ...

BIOTECH HAS DEVELOPED A SYSTEM FOR LABELING DNA FRAGMENTS WITH HAPTEN-MODIFIED ""TAILS'' WHICH CAN BE DETECTED BY IMMUNOLOGICAL METHODS USING ENZYME-CONJUGATED ANTIBODIES. THE DETECTION SENSITIVITY OF THIS SYSTEM IS 274 PICOGRAM, WHICH IS SUFFICIENT TO DETECT SINGLE COPY GENES IN HUMAN DNA. THE AIM OF THIS PROPOSAL IS TO TEST THE APPLICABILITY OF BIOTECH'S SYSTEM FOR DIAGNOSTIC USE IN CLINICAL LAB ...

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DESCRIPTION (provided by applicant): Hematopoietic cell-supported therapy is employed for a broad spectrum of malignancies and hematological disease. However, the approach is limited by the availability of hematopoietic stem cells; thus, the possibilit

DESCRIPTION (provided by applicant): Up-regulation of COX-2 has also been reported to occur in human brains following a lethal cerebral ischemic insult and selective inhibition of COX-2 has been demonstrated to be neuroprotective in animal models. In addition, there has been a voluminous literature that suggests that cyclooxygenase-2 (COX-2) may contribute to neuronal injury in various neurodegene ...

DESCRIPTION (provided by applicant): Strategies aimed at limiting and repairing the damage attributed to oxidative stress may slow the advance of numerous age-related diseases. Numerous studies indicate that the enzyme cyclooxygenase-2 (COX-2) is induced by oxidative stress, contributes to oxidative stress, and promotes subsequent neuronal injury. In this application we propose continuation of our ...

109 Use of Novel, Low-Cost Additives to Improve Sorbent Efficiency for Control of Mercury Emissions in Coal-Fired Power Plant Flue Gases--Physical Sciences Inc., 20 New England Business Center, Andover, MA 01810-1022; Mr. Joseph R. Morency, Principal Investigator Mr. George E. Caledonia, Business Official DOE Grant No. DE-FG02-97ER82456 Amount: $74,996 Although coal-fired power plants are n ...

A 6-month, Phase I Small Business Innovation Research (SBIR) program is proposed to conduct proof-of-principle work on a novel process which uses momentum transfer mechanisms and liquid carbon dioxide for all-dry wafer cleaning. Under an earlier, Phase I project, the basic principle of momentum transfer has been demonstrated as effective, using high purity liquid carbon dioxide sprays accelerated ...

The global population is expected to reach 9.7 billion people by 2050 with food demand to increase by 70% during that time (van Huis, A. et. al, 2015 and Shockley, 2014). Nearly 200 million children worldwide suffer from malnutrition with the World Health Organization estimating that 54% of child mortality is the result of malnutrition (Shockley, 2014). With land and water use already stressed wit ...

Roughly 8 million metric tons of plastic waste pollute the world’s oceans annually and detrimentally impact the environment. It is estimated that ocean plastic waste costs society up to $2.5 trillion/year. Abandoned fishing nets, one type of ocean plastic waste, are a major threat to marine habitats and biodiversity.These “ghost nets” account for 52% of the Great Pacific Garbage Patch where ...