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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

Displaying 196191 - 196200 of 207712 results
  1. Not Available

    SBC: STELLARRAY INC            Topic: NCI

    Stellarray proposes to develop a novel, high-intensity version of its digitally-addressable (pixilated) x-ray source (HI-DAXS) for use in cancer imaging applications. Preliminary work at Stellarray has shown the basic feasibility of a reflective-mode, digitally-addressable x-ray source. The overall goal of the proposed project is to address the key issues - high current density pixels for the cath ...

    SBIR Phase I 2011 Department of Health and Human ServicesNational Institutes of Health
  2. Not Available

    SBC: XINTEK, INC.            Topic: NCI

    Breast cancer is the most common cancer type among women. Early detection is viewed as the best approach to decrease breast cancer mortality. Digital breast tomosynthesis (DBT), a 3-D imaging modality, is generally considered as the next generation screening device with improved performance compared to the full-field digital mammography. The current DBT scanners however suffer from low spatial res ...

    SBIR Phase I 2011 Department of Health and Human ServicesNational Institutes of Health
  3. Not Available

    SBC: TETRAIMAGING LLC            Topic: NCI

    Tetrahedron Beam Computed Tomography (TBCT) is an innovative x-ray imaging system with improved mobility, speed, image quality and reduced cost. It can be used in image guided intervention as well as a mobile diagnostic CT scanner. Through this project wewill develop the key component of TBCT the multiple pixel x-ray source. The tube will comprise multiple thermionic cathodes in 10 array with 4 mm ...

    SBIR Phase I 2011 Department of Health and Human ServicesNational Institutes of Health
  4. AN OPTICALLY-BASED RNA BIOSENSOR

    SBC: CHROMOLOGIC LLC            Topic: NCI

    Accurately detecting early cancer biomarkers can dramatically improve cancer treatment and prevention. Non-coding RNAs (ncRNAs) have recently shown promise as cancer-related biomarkers that could be used in early detection and treatment of cancer. However,current methods for detection of ncRNAs are time-intensive and costly, precluding their application to quantitative ncRNA screening on a massive ...

    SBIR Phase I 2011 Department of Health and Human ServicesNational Institutes of Health
  5. ADAPTING PADLOCK-PROBE DETECTION SYSTEMS TO NCRNA DETECTION FOR CANCER DIAGNOSTICS

    SBC: CUSTOMARRAY, INC.            Topic: NCI

    This proposal seeks to develop a cancer diagnostic based on microRNA (miRNA) expression patterns found in human serum. Mounting evidence is showing that patterns of miRNA expression and the appearance of these signals in circulating extra-cellular compartments are hallmarks of proliferating tumor cells. Our preliminary results have shown a clear ability to distinguish sera derived from cancer pati ...

    SBIR Phase I 2011 Department of Health and Human ServicesNational Institutes of Health
  6. RAPID MULTIPLEXED DETECTION OF CANCER RELATED PROTEINS

    SBC: GENALYTE, INC.            Topic: NCI

    "Rapid Multiplexed Detection of Cancer Related Proteins" The contractor will utilize a multiplexed label-free platform developed by the contractor with potential to realize sensitive and high-throughput analysis of proteins in clinical samples. This technology will be used throughout the contract to demostrate how it can be used for cancer marker screening.

    SBIR Phase I 2011 Department of Health and Human ServicesNational Institutes of Health
  7. CANCER-RELATED BIOMARKER DETECTION SYSTEM

    SBC: EVEIA MEDICAL            Topic: NCI

    "Cancer-Related Biomarker Detection System" The contractor will utilize a low throughput automated instrument developed by the contractor that is capable of detecting analytes at concentrations as low as 100 femtomolar. The instrument is based on a proprietary sandwich immunoassay that is entirely solution phase, dramatically increasing kinetic rates while reducing background. The Phase I project ...

    SBIR Phase I 2011 Department of Health and Human ServicesNational Institutes of Health
  8. MULTIPLEXED BIOSENSOR FOR DETECTING LOW ABUNDANCE CANCER

    SBC: PHOENIX BIOSYSTEM, INC.            Topic: NCI

    Title: Multiplexed Biosensor for Detecting Low Abundance Cancer Description: The proposed automated, miniaturized, highly sensitive, high throughout affinity/protein capture technology could be a powerful tool for the quantitative detection of known cancerprotein markers and the discovery of new tumor markers. This biosensor array platform will be easily adaptable to new markers that better detect ...

    SBIR Phase I 2011 Department of Health and Human ServicesNational Institutes of Health
  9. SBIR PHASE I AWARD

    SBC: ARAVASC, INC.            Topic: NCI

    Esophageal cancer is a deadly disease with limited treatment options. In addition to modest effects, toxic chemo-therapy drugs cripple patients with debilitating side-effects. This proposal utilizes an Esophageal Theranostic Delivery System (ETDS), to address this clinical need with a multi-modal solution. It delivers a theranostic combination of chemotherapy drugs and a fluorescent dye directly t ...

    SBIR Phase I 2011 Department of Health and Human ServicesNational Institutes of Health
  10. RandD-OTHER SCIENCES-B RES

    SBC: QUALIBER, INC.            Topic: NCI

    Gemcitabine (Gemzar) is an effective chemotherapeutic drug approved for treatment of several cancers, including non-small cell lung cancer (NSCLC), pancreatic, breast and ovarian cancer. However, its use has been limited due to its short half-life and significant systemic toxicity. This proposal utilizes a novel Lipid-Calcium-Phosphate (LCP) nanoparticle platform for the design of multifunctional ...

    SBIR Phase I 2011 Department of Health and Human ServicesNational Institutes of Health
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