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Award Data

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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

Displaying 196301 - 196310 of 207699 results
  1. Multitargeted Therapy for Age-related Macular Degeneration

    SBC: Charlesson, LLC            Topic: NEI

    DESCRIPTION (provided by applicant): Age-related macular degeneration (AMD) is a sight-threatening disease which represents the leading cause of blindness and visual impairment in elderly individuals in developed countries. Recently, laser and photodynamic therapies with limited clinical benefit have been partially replaced by anti-vascular endothelial growth factor (VEGF) therapies. Clinical ...

    SBIR Phase I 2011 Department of Health and Human ServicesNational Institutes of Health
  2. Adaptive Retina-Tracking Optical Coherence Tomography System

    SBC: Physical Optics Corporation            Topic: NEI

    DESCRIPTION (provided by applicant): It is widely know that if retinopathy and specifically diabetic retinopathy are not duly detected and controlled through medical interventions, they can progress into a proliferative retinopathy and cause significant decrease in visual acuity and blindness. It is estimated that in 2008, approximately 24 million in the U.S. [1] and ...

    SBIR Phase I 2011 Department of Health and Human ServicesNational Institutes of Health
  3. Microtechnology-Enhanced Surgical Device For Pediatric Lens Capsulotomy And Treat

    SBC: Mynosys Cellular Devices, Inc.            Topic: NEI

    DESCRIPTION (provided by applicant): We propose a new interventional device that solves a significant therapeutic bottleneck in the treatment of lens cataract in children. As the leading cause of childhood blindness, lens cataract interferes with the optical performance of the eye and if untreated, results in lifelong deficits in visual perception. The first step in pediatric cataract surgery is t ...

    SBIR Phase I 2011 Department of Health and Human ServicesNational Institutes of Health
  4. Anti-angiogenesis of HC-HA Covalent Complex and PTX3 Purified from Fetal Membrane

    SBC: BIOTISSUE HOLDINGS INC.            Topic: NEI

    DESCRIPTION (provided by applicant): Angiogenesis is a part of adult wound healing, which starts from inflammation and may end in scarring. When inflammation, angiogenesis, and scarring are well controlled, adult wound healing results in the restoration oftissue function. In contrast, pathologic angiogenesis that is frequently associated with uncontrolled inflammation may lead to pathologic scarri ...

    SBIR Phase I 2011 Department of Health and Human ServicesNational Institutes of Health
  5. Novel emulsion-based formulation of the anti-glaucoma MSH-1001 for improved topic

    SBC: Charlesson, LLC            Topic: NEI

    DESCRIPTION (provided by applicant): This Small Business Innovation project aims to develop an innovative eye drop formulation for the treatment of glaucoma and ocular hypertension. Charlesson has acquired from Danube Pharmaceuticals MSH-1001, a new smallmolecule compound (previously known as DNB-001 or KR- 31378). MSH-1001 is has both ocular hypotensive and neuroprotectant properties. It is an AT ...

    SBIR Phase I 2011 Department of Health and Human ServicesNational Institutes of Health
  6. Prevention of Retinopathy of Prematurity with a Novel Bifunctional Redox Reagent

    SBC: RADIKAL THERAPEUTICS, INC.            Topic: NEI

    DESCRIPTION (provided by applicant): Retinopathy of prematurity (ROP) is present in up to 70-85% of very low birthweight premature infants (lt 1 kg). The more severe forms of ROP (Grades 3-5) account for more than 50% of injuries and are associated with lifelong visual impairment, including blindness. There are no pharmaceutical agents, or other measures, approved for the prevention of ROP. A ...

    SBIR Phase I 2011 Department of Health and Human ServicesNational Institutes of Health
  7. Vision-QOL-CAT: A Functional Health CAT for those with Visual Disorders

    SBC: John Ware Research Group, Inc.            Topic: NEI

    DESCRIPTION (provided by applicant): With the aging of the population, vision loss is a growing public health problem affecting more than 3 million Americans. The impact of eye disease on health-related quality of life (HRQOL) and the benefits of new treatments are not well understood and have not been compared with those for other medical conditions. Although self-assessment tools for measuring t ...

    SBIR Phase I 2011 Department of Health and Human ServicesNational Institutes of Health
  8. Advanced Laser Source for High-speed Adaptive Optics OCT

    SBC: PHYSICAL SCIENCES INC.            Topic: NEI

    DESCRIPTION (provided by applicant): Physical Sciences Inc. (PSI) proposes to develop a new adaptive optics imaging approach to high- speed 3D-retinal mapping with enhanced Fourier Domain Mode-locked (FDML) swept-source technology. PSI is currently engaged in ongoing development of high performance, high resolution multimodal adaptive optics (AO) retinal imagers. Such systems resolve and quant ...

    SBIR Phase I 2011 Department of Health and Human ServicesNational Institutes of Health
  9. Gaze-guided Localized Image Magnification Peripheral Sight Enabler for Low Vision

    SBC: SMART ENGINEERING            Topic: NEI

    DESCRIPTION (provided by applicant): Central vision field loss (CFL) is caused by inherited and acquired diseases that irreversibly damage the fovea while leaving the peripheral retina relatively intact. CFL results in 1,700,000 legal blindness and lowvision (LV) cases in the US. LV rehabilitation is the means of restoring functional abilities modified by CFL so that the patient's quality ...

    SBIR Phase I 2011 Department of Health and Human ServicesNational Institutes of Health
  10. Vision Impaired Wayfinding with Doppler Velocimeter

    SBC: Koronis Biomedical Technologies Corp.            Topic: NEI

    DESCRIPTION (provided by applicant): The objective is to use a new innovative sensor technology called a Doppler velocimeter (DV) for solving the problem of wayfinding indoors for the vision impaired. By performing a Doppler measurement of the floor movement relative to the walking person it is possible to determine the along-track velocity, the cross-track velocity and the vertical (up or dow ...

    SBIR Phase I 2011 Department of Health and Human ServicesNational Institutes of Health
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