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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

Displaying 196301 - 196310 of 207712 results
  1. Development and validation of a sample-to-answer metagenomics workflow for comprehensive pathogen detection in central nervous system infections

    SBC: ARC Bio, LLC            Topic: NIAID

    ABSTRACT This research will ultimately advance human health by improving the diagnosis and treatment of central nervous system infections including meningitis and encephalitis, where the causative pathogen is not identified in up to 50% of cases. These infections are associated with significant morbidity and mortality; therefore, rapid and accurate diagnosis is crucial for appropriate patient mana ...

    SBIR Phase II 2022 Department of Health and Human ServicesNational Institutes of Health
  2. Novel assay to detect integrated HBV DNA in urine of chronic hepatitis B patients

    SBC: JBS SCIENCE INC            Topic: NIAID

    Novel assay to detect integrated HBV DNA in urine of chronic hepatitis B patients Hepatitis B virus (HBV) infection is a global public health concern. The CDC estimates that up to 2 million Americans are chronically infected with HBV. HBV infection causes acute and chronic hepatitis, the latter often leading to severe liver diseases such cirrhosis and HBV-associated hepatocellular carcinoma (HBV-H ...

    SBIR Phase I 2022 Department of Health and Human ServicesNational Institutes of Health
  3. Preventing outbreaks of foodborne pathogenic bacteria in edible sprouts via novel resistance-conferring seed treatments

    SBC: Ascribe Bioscience Inc.            Topic: NIAID

    Abstract Ascribe Bioscience is developing a novel technology to prevent foodborne outbreaks caused by the consumption of edible sprouts. Sprouts are highly vulnerable to infection with human enteric bacterial pathogens at the seed stage. These pathogens then grow exponentially in the warm and humid conditions used for sprouting. Even low initial bacterial counts on seeds can result in unsafe micro ...

    SBIR Phase II 2022 Department of Health and Human ServicesNational Institutes of Health
  4. Improving Patient Care Through Objective Monitoring of At-Home Repetitive Ritual Behaviors in Obsessive-Compulsive Disorder

    SBC: ADVANCED MEDICAL ELECTRONICS CORP            Topic: 104

    Project Summary Obsessive-compulsive disorder (OCD) is characterized by intrusive, distressing thoughts (obsessions) in response to which an individual feels compelled to perform a repetitive behavior (compulsions), which are performed in order to reduce the acute distress experienced by the patient but which perpetuate OCD symptoms. Effective treatment requires accurate reporting of compulsive be ...

    STTR Phase I 2022 Department of Health and Human ServicesNational Institutes of Health
  5. MentorHub: A Supportive Accountability Tool for MHapps

    SBC: ACADEMIC WEB PAGES, INC            Topic: 104

    Project Summary/Abstract (30 lines) In the United States, 15 million children and adolescents need psychological services; yet only one-third receive psychological services of any kind. Even fewer receive care that is consistent with evidence-based guidelines for best practices. This gap has widened dramatically with the negative effects of the COVID-19 pandemic on the mental health of children, c ...

    STTR Phase I 2022 Department of Health and Human ServicesNational Institutes of Health
  6. Compact Laser Drivers for Photoconductive Semiconductor Switches- STTR Phase II Sequential

    SBC: SCIENTIFIC APPLICATIONS & RESEARCH ASSOCIATES, INC.            Topic: DTRA16A004

    For effective protection against radiated threats, produced by high altitude electromagnetic pulse (HEMP) caused by nuclear detonations and high-power microwave (HPM) Directed Energy (DE) weapons it is important to understand not only the physics of the threats, but also to quantify the effects on mission-critical electrical systems. EMP/HMP simulators enable threat level testing of MCS and provid ...

    STTR Phase II 2022 Department of DefenseDefense Threat Reduction Agency
  7. Commercialization readiness of visual biofeedback to reduce head motion during MRI scans

    SBC: TURING MEDICAL TECHNOLOGIES INC            Topic: NIMH

    Project Abstract/SummaryThe goal of this CRP application is to successfully commercialize a brain MRI technology that feeds back head motion measurements derived from our Framewise Integrated Real-Time MRI Monitoring (FIRMM) software to MRI scan participants in order to reduce head motion via behavioral training. Because MRI scanning produces high-resolution images and does not expose patients to ...

    SBIR Phase II 2022 Department of Health and Human ServicesNational Institutes of Health
  8. HYBRID TYPE 1 EFFECTIVENESS-IMPLEMENTATION TRIAL FOR PRIMARY CARE DEPRESSION SCREENING AND REFERRAL TO A REMOTE DIGITAL MENTAL HEALTH CLINIC

    SBC: Meru Health Medical, P.A.            Topic: 104

    ABSTRACT The global burden of depression is staggering: Affecting an estimated 7 to 10% of the adult U.S. population in any given year, depression’s high rates of comorbid conditions and association with impaired functioning and disability costs the U.S. approximately $200 billion per year. Issues continue to plague screening, recognition, and treatment for depression in primary care settings. P ...

    SBIR Phase II 2022 Department of Health and Human ServicesNational Institutes of Health
  9. Development of a Frontier Magnetic Resonance (MR) Imaging Technology As a Tool for Visualization and Quantified Vascular-Feature Measurement for Use in Brain and Behavioral Research on Small Animals

    SBC: IMAGINOSTICS, INC            Topic: 101

    PROJECT SUMMARY The burden of mental illness continues to be a growing challenge in the United States. At the same time, the scientific community continues to study the brain and behavior, revealing relationships between brain structure and function and physiology and illness. The outer scope of brain and behavior research is governed by the imaging and analytical tools available to scientists. Ma ...

    SBIR Phase I 2022 Department of Health and Human ServicesNational Institutes of Health
  10. Microscope system for large scale optical imaging of neuronal activity using kilohertz frame rates

    SBC: MICROBRIGHTFIELD, LLC            Topic: 105

    Abstract This project aims to develop the 2P-ActivityScope™, a revolutionary new microscope based on a technological breakthrough called second-generation Scanned Line Angular Projection (SLAP2) two photon laser scanning microscopy that was recently developed by Dr. Kaspar Podgorski (Janelia Research Campus, Howard Hughes Medical Institute, Ashburn, VA). The game-changing innovation in the 2P-Ac ...

    SBIR Phase I 2022 Department of Health and Human ServicesNational Institutes of Health
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