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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

Displaying 196311 - 196320 of 207712 results
  1. Technology-based training to improve learning-to-drive outcomes for autistic persons

    SBC: Minnesota HealthSolutions Corporation            Topic: NICHD

    Project Summary/Abstract The goal of the proposed project is to make the widespread use of an autistic driver training program feasible. Specifically, we plan in phase I to develop an innovative learn-as-you-go training module and in phase II to rewrite the app for a variety of devices and operating systems. The program teaches visual search skills to autistic individuals who are learning to drive ...

    SBIR Phase I 2022 Department of Health and Human ServicesNational Institutes of Health
  2. Community-based Brain Health Program to Address Dementia Risk (C-BBHP)

    SBC: POSIT SCIENCE CORP            Topic: NIA

    PROJECT SUMMARY The goal of the current Phase I proposal is to further develop (to pivotal trial readiness) and evaluate a community-based Brain Health Program to address dementia risk (C-BBHP) that includes multiple intervention modalities affecting diet, exercise and cognitive health designed to extend older adults’ functional independence and improve cognitive performance. This intervention m ...

    SBIR Phase I 2022 Department of Health and Human ServicesNational Institutes of Health
  3. Development of a salt-based nanomedicine for non-muscle invasive bladder cancer

    SBC: ATHNA BIOTECH INC            Topic: 102

    AbstractBladder cancer comprises 7% of new cancer diagnoses in the US. It is the sixth most prevalent malignancy, and has the highest lifetime treatment costs among all cancer types due to the need for lifelong surveillance. Early stage bladder cancer, also known as non-muscle-invasive bladder cancer (NMIBC), represents 75% of new bladder cancer cases. The standard treatment is transurethral resec ...

    SBIR Phase I 2022 Department of Health and Human ServicesNational Institutes of Health
  4. A Mucus-producing Intestinal Epithelium Model for In Vitro Drug Absorption Testing

    SBC: Altis Biosystems, Inc.            Topic: 300

    Project SummaryThe mucus layer is the first line of defense against infiltration of microorganisms, digestive enzymes and acids, digested food particles, microbial by-products, and food-associated toxins. This layer coats the interior surface of the GI tract, lubricates luminal contents and acts as a physical barrier to bacteria and other antigenic substances present in the lumen. The moist, nutri ...

    SBIR Phase I 2022 Department of Health and Human ServicesNational Institutes of Health
  5. Pharmacological induction of KLF2 and reversal of endothelial dysfunction for the treatment of hypertension

    SBC: RIPARIAN PHARMACEUTICALS INC            Topic: NHLBI

    PROJECT SUMMARY There is a clear unmet need for new differentiated anti-hypertensive therapies, as high blood pressure and its pathological sequelae remain significant burdens to human health despite several classes of approved drugs. The vascular endothelium is a dynamic interface that regulates vasotone, inflammation, hemostasis and vascular remodeling. Dysfunction of the vascular endothelium, i ...

    SBIR Phase I 2022 Department of Health and Human ServicesNational Institutes of Health
  6. Selective antimicrobial peptides from milk for bacterial vaginosis

    SBC: Matrubials, Inc.            Topic: NIAID

    Project Abstract Several currently administered antibiotics raise two main concerns: resistance and non-selectivity. The rapid rate of emerging multi-drug resistance poses a global health threat and dramatically increases economic burden. With traditional antibiotics being largely non-selective, there are serious side effects due to the natural host microbiome being modified, and thus a loss in ho ...

    SBIR Phase I 2022 Department of Health and Human ServicesNational Institutes of Health
  7. An assistive-technology based Caregiver Training Program (CTP) to enhance caregiver effectiveness, well-being, and quality of life, which will improve overall care for individuals living with AD/ADRD.

    SBC: MAPHABIT INC            Topic: R

    Project Summary Abstract The MapHabit System (MHS) is our neuroscience-based interactive care management platform that utilizes a patented visual mapping system supported by smart devices to improve cognition and reinforce routine habits in individuals living with AD/ADRD. The MHS approach relies on the discovery that certain regions of the brain that underlie habit and procedural learning are spa ...

    SBIR Phase I 2022 Department of Health and Human ServicesNational Institutes of Health
  8. Culture and amplification-free bacterial sepsis diagnosis

    SBC: SCANOGEN INC.            Topic: NIAID

    Culture and amplification-free bacterial sepsis diagnosis Summary Sepsis is a life-threatening complication of an infection that requires immediate treatment. The identification of the causative microorganism utilizing processes based on blood culture is a keystone of sepsis diagnosis. However, blood culture takes one to five days to provide results. Here, we propose the development of a culture a ...

    SBIR Phase I 2022 Department of Health and Human ServicesNational Institutes of Health
  9. Development of novel Aquilo Heat Therapy Device to treat patients with PeripheralArtery Disease

    SBC: AQUILO SPORTS L.L.C            Topic: NHLBI

    The objective of this proposal is to develop a novel device to provide leg heat therapy (HT) for patients with symptomatic peripheral arterial disease (PAD). The current non-interventional standard of care for PAD is a 12 week program of supervised exercise therapy (SET). For patients this is often very painful as they are exercised to the point of claudication and many elderly patients find it di ...

    SBIR Phase I 2022 Department of Health and Human ServicesNational Institutes of Health
  10. Low-Cost Refreshable Full-Page Braille Display with High Reliability

    SBC: POLYK TECHNOLOGIES LLC            Topic: NEI

    Project SummaryPolyK Technologies, LLCSBIR Phase IAn estimated 314 million people live with vision impairment. Nowadays, much information and knowledge are obtained by reading from computers, tablets, and smartphones. Refreshable Braille display is becoming the mainstream tool for the blind to access digital information. In the refreshable Braille display, the up-and-down of Braille dots is indepe ...

    SBIR Phase I 2022 Department of Health and Human ServicesNational Institutes of Health
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