Award Data

Knee and shoulder surgery patients are at high risk of becoming addicted to opioids that are prescribed to manage pain after their surgery. Each year, from the 1.475 million knee/shoulder surgeries performed in the United States, an estimated 167,000 people, and another 17,000 of their friends and family, will become addicted to opioids. Limited options for disposal of unused opioids, such as drug ...

Project Summary About 750,000 Americans and approx. 4.5 million patients worldwide have End-Stage Renal Disease (ESRD)1– 3. Aging population as well as rise in ESRD-related comorbidities are key factors in the anticipated rate of increase in patients with ESRD4. One of the primary causes for this high morbidity and mortality are the complications associated with maintaining a functioning vascula ...

Project Summary/Abstract Pancreatic ductal adenocarcinoma (PDAC) is one of the deadliest forms of cancer. Poor survival rates are largelydue to the late stage at which PDAC is diagnosed and a lack of effective targeted therapies. While the field ofimmunotherapy has significantly increased overall survival in some malignancies, they have not translated toPDAC. The long-term goal of this research pr ...

ABSTRACT We are developing and sensor, the X-VISUAL (X-ray Visualized Indicator for Screw bending Under Applied Load), to track fracture healing in canulated screws used to treat hip fractures. Hip fractures are a major public health concern with high in-hospital mortality rate. Approximately 330,000 hip fixation procedures are performed annually in the US. The average hip fixation hardware failur ...

ABSTRACT Background: In the U.S., over 200,000 girls and women age 0-49 are diagnosed with cancer annually. While improved diagnosis and treatment have led to increased survival rates (75% in premenopausal and 85% in childhood cancer patients), devastating side effects of cancer therapies include premature ovarian failure, infertility and menopause-related health risks. The current industrial stan ...

ABSTRACT The kidney transplant waitlist comprises 83% of the U.S. organ transplant waitlist. Yet, for every 5 patients who die or become too sick for transplantation, 3 kidneys are discarded. Organ preservation quality is linked to graft lifespan with kidneys having only 50% graft survival after 10 years. Extending preservation to a week, or longer, would enable nationwide (theoretically global) d ...

Ravensafe provides a portable energy storage solution that negates the use of fuel generators for providing instant power. The portable energy storage system can be recharged by grid power, solar, or generator. The power is stored in a hybrid lithium ion

Security Forces is transitioning to a new Weapons Qualifications Course that will significantly increase the number of iterations that Defenders conduct at the firing range. Going forward, all personnel will receive firearms training on a monthly/quarterly basis (as opposed to annually) at outdoor ranges with distances of 25 - 400 meters.  Bullseye Targets Systems LLC has developed the Bullseye T ...

Istari, partnering with the Sensing Perception Autonomy and Robot Kinetics (SPARK) Lab at MIT, proposes to study the feasibility of integrating pose estimation and object detection algorithms developed at MIT into the Air Force digital aircraft design certification procedure to target improved model performance.  The SPARK Lab has developed highly accurate methods to certify pose estimations and ...

At a high level, the major mission focus of this research is:  How can the DAF and broader DoD leverage Zero Trust methodology into digital model sharing and collaboration? The technical focus of this research is:  What is the best manner to link digital