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Award Data

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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. An Intraoperative Guidance Platform for Radio Frequency Ablation

    SBC: NE SCIENTIFIC LLC            Topic: NCI

    DESCRIPTION (provided by applicant): The objective of this proposed research program is to develop a platform for planning and guidance during Radio Frequency Ablation (RFA). RFA is a thermally mediated ablation technique, where an applicator carrying oneelectrode is inserted into tumors percutaneously (or via laparoscopy, or open surgical approaches). Radio Frequency (RF) energy is applied, denat ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  2. Peptide-Derived Orally-Active Kappa-Opioid Receptor Agonists for Peripheral Pain

    SBC: HALIMED PHARMACEUTICALS, INC.            Topic: NIDA

    DESCRIPTION (provided by applicant): Treatment of peripheral pain of various origins remains a major unmet medical need, affecting tens to hundreds of millions of people nationwide at some time during their lives. Kappa-opioid agonists have been shown in peripheral pain models to be particularly efficacious but suffer from centrally mediated effects that have limited their development. Perhaps the ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  3. Adolescent Screener and Opioid Assessment for Patients with Pain (A-SOAPP)

    SBC: Inflexxion, Inc.            Topic: NIDA

    DESCRIPTION (provided by applicant): Pain management including the use of opioid analgesics is recommended for adolescents who are suffering from recurrent or chronic pain associated with a specific etiology such as cancer, cystic fibrosis, sickle cell anemia, hemophilia or organ transplants (see citations by etiology in letter of support from CO-I, Dr. Solodiuk). Preventive screening tools provi ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  4. Cannabinergic Receptor Antagonists for Nicotine Addiction

    SBC: MAKSCIENTIFIC            Topic: NIDA

    DESCRIPTION (provided by applicant): Existing evidence in animals and man indicates that blockade of the CB1 receptor may offer an effective approach for combating nicotine addiction. Early studies in humans have documented these effects. This Phase I application proposes studies to design advanced CB1 pyrrolidinone antagonists toward the development of medications for smoking cessation. Our inten ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  5. Phone app for grounding (de-escalation) of substance-abusing transition-age youth

    SBC: TREATMENT INNOVATIONS, LLC            Topic: NIDA

    DESCRIPTION (provided by applicant): Substance use disorder (SUD) is the second most common psychiatric diagnosis in the U.S. population, with 14.6% developing it in their lifetime. Transition-age youth (TAY) from ages 18-24 are especially vulnerable to substance use, misuse, and SUD. This developmental period, termed the age of instability includes tasks such as leaving home; entering college; ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  6. Integrating optical coherence tomography with laryngeal high-speed videoendoscopy

    SBC: PHYSICAL SCIENCES INC.            Topic: NIDCD

    DESCRIPTION (provided by applicant): There is a growing clinical need for improving the assessment of vocal fold tissue properties in vivo, especially dynamic properties measured during human voice production. To address this need, Physical Sciences Inc. (PSI), in collaboration with MGH Voice Center, will develop a clinically-viable imaging system that will integrate optical coherence tomography ( ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  7. Functional otoscopy for non-invasive diagnosis of middle ear pathologies

    SBC: PHYSICAL SCIENCES INC.            Topic: NIDCD

    DESCRIPTION (provided by applicant): There is a growing clinical need for improving the non-invasive diagnostic capabilities of middle ear pathologies in vivo. To address this need, Physical Sciences Inc. (PSI), in collaboration with the Eaton Peabody Labat the Massachusetts Eye and Ear Infirmary (MEEI), will develop a clinically viable otoscopic imaging system that will employ phase sensitive opt ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  8. Customized nanotechnology based treatment of Oral Cancer

    SBC: PRIVO TECHNOLOGIES, LLC            Topic: NIDCR

    DESCRIPTION (provided by applicant): According to the Oral Cancer (OC) Foundation, oral and pharyngeal cancer will cause 8,000 deaths this year, killing roughly one person per hour. Currently, cisplatin (CIS) is at the forefront of platinum- based chemotherapeutics for treating OC. However, its efficacy is often hindered by its significant systemic toxicity as a result of traditional bolus systemi ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  9. Engineered Neurotensin Fragments Targeting Neuropathic Pain

    SBC: JT Pharmaceuticals, Inc.            Topic: NIDCR

    DESCRIPTION (provided by applicant): Neuropathic pain management is a major unmet clinical need. Classically used medications, including opioids and non-opioids (primarily NSAIDs), have major side effects associated with their use, and many individuals donot respond to any medications. Neuropathic pain drugs with novel mechanisms of action are being sought as an alternative; however, the only succ ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  10. Parents.Cope: A tool for Parents of Adolescents with T1DM

    SBC: New England Research Institutes, Inc.            Topic: NIDDK

    PROJECT SUMMARY/ABSTRACT Type 1 diabetes (T1DM) is the most common chronic illness in children, affecting 1 in 400 with evidence that its prevalence is increasing worldwide. Parents of children with T1DM are responsible for a labor-intensive and complicated daily regimen that has been described as an overwhelming experience, requiring constant vigilance. The prevalence of anxiety symptoms for par ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
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