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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Geriatric Symptom Protocols for Improved Triage in Offices and Assisted Living

    SBC: KEONA HEALTH, INC.            Topic: NINR

    DESCRIPTION (provided by applicant): For medical practices, a major challenge is managing the hundreds of telephone calls received daily, many of which are about new or worsening medical symptoms. Particularly difficult are calls from persons with little or no medical training about frail older persons living at home or in assisted living (AL) communities. Incoming calls are typically answered by ...

    STTR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  2. High Z Oraya Therapy for wet AMD

    SBC: ORAYA THERAPEUTICS, INC            Topic: NEI

    Project Description The purpose of this project is to develop a new radiotherapy treatment modality that will substantially enhance the treatment of wet AMD with minimal toxicity to healthy tissue, leading to major improvement in visual acuity, decreaseduse of intravitreal injections of anti-VEGF agents, lower cost of treatment, and a substantially improved quality of life for patients. The new m ...

    STTR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  3. Identification and Quantification of Sequence Specific RNA Modifications via the Alpha-Hemolysin Latch Zone

    SBC: ELECTRONIC BIOSCIENCES, INC.            Topic: NIDA

    DESCRIPTION (provided by applicant): During this STTR program, Electronic BioSciences (EBS) proposes to develop a nanopore based system around our University of Utah collaborators newly developed technology that will be capable of identifying and quantifying sequence specific RNA modifications. A system capable of quantitative, low cost, high throughput, RNA modification characterization has the c ...

    STTR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  4. Intra-procedure Deformable Ultrasound-MRI Fusion for Prostate Biopsies

    SBC: ZMK Medical Technologies, Inc.            Topic: NCI

    This proposal is a collaborative effort between Yale University and the medical device company Eigen to develop a more robust and accurate method for the deformable fusion of pre-operative magnetic resonance images (MRI) and intra-procedure trans-rectal ultrasound (TRUS) images to guide prostate biopsy. Prostate cancer is a major cause of death in the U.S. and biopsy is the gold-standard for its d ...

    STTR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  5. Lateral Flow Immunoassays For Pharmacokinetic Dosing Of Monoclonal Antibodies

    SBC: ABREOS BIOSCIENCES, INC.            Topic: NCI

    DESCRIPTION (provided by applicant): Monoclonal antibodies (mAb) are used to treat a variety of cancers and other diseases. Dosing is typically based on body surface area, but population pharmacokinetic (PK) data suggests considerable variation across patients. Furthermore, there is growing evidence that patients with low final trough levels of circulating antibody have a poorer outcome, suggestin ...

    STTR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  6. Low-Cost Instrument-free Point-of-care Platform for Multiplexed Chlamydia Diagnos

    SBC: Lucira Health, Inc.            Topic: NIAID

    DESCRIPTION provided by applicant Detecting Chlamydia Ct STIs at the point of care POC represents a critical unmet medical need Development of an effective Ct POC diagnostic will result in widespread screening efforts for rapid diagnosis to inform treatment and evaluate treatment efficacy and for test of cure that would not only reduce the acute and chronic morbidity that is directly asso ...

    STTR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  7. Manufacture of Self-Reporting, Drug Loaded Porous Silicon Nanomaterials for Treat

    SBC: SPINNAKER BIOSCIENCES, INC.            Topic: NEI

    PROJECT SUMMARY/ABSTRACT Visual impairment is a global epidemic affecting millions of individuals currently. A large portion of these individuals suffer from chronic age-related macular degeneration (AMD), characterized by progressive neovascularization and vascular leakage near the central region (macula) of the retina. Current treatments for AMD, including laser photocoagulation, photodynamic th ...

    STTR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  8. Mitochondrial Antioxidant Neurodegenerative Therapeutics: XJB-5-131 Derivatives

    SBC: SOLANO PHARMACEUTICALS, INC.            Topic: NINDS

    DESCRIPTION (provided by applicant): Oxidative damage to mitochondrial is a major source of toxicity in diseases such as Alzheimer's (AD), Parkinson's (PD), and Huntington's diseases (HD). Mitochondria are energy powerhouses of the cell, and decline in their function by oxidative damage is a common feature among neurodegenerative diseases. Despite years of effort, however, generic ...

    STTR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  9. Modernize animal pharming with emerging gene targeting technologies

    SBC: APPLIED STEMCELL, INC.            Topic: NIGMS

    DESCRIPTION (provided by applicant): Animal pharming is the process of using transgenic animals to produce human drugs, mostly in the mammary glands of female animals. The US Food and Drug Administration (FDA) issued its first approval for ATryn, the recombinant human antithrombin III, produced in the milk of transgenic goats in 2009. Prior to FDA approval, this drug gained the approval by the Eu ...

    STTR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  10. New Class of Bright, Sharp, Tunable Near-Infrared Fluorophores for Flow Cyto

    SBC: Nirvana Sciences, Inc.            Topic: NIAID

    DESCRIPTION (provided by applicant): Polychromatic flow cytometry [FC] is one of the most powerful analytical techniques routinely used in immunology. Flow cytometry plays a critical role in several growing clinical applications: leukemia and lymphoma immunophenotyping for diagnosis and sub-categorization (now using 8-10 colors); in CD4/CD8 measurement in HIV-positive patients; and in HLA typing f ...

    STTR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
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