You are here
Award Data
The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.
Download all SBIR.gov award data either with award abstracts (290MB)
or without award abstracts (65MB).
A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.
The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.
-
Polo box PLK Inhibitors Target Tumors Resistant to ATP Competitive Compounds
SBC: PPI PHARMACEUTICALS, LLC Topic: NCIPolo like kinase PLK is a central player in regulating entry into and progression through mitosis Many studies have validated PLK as an anti tumor drug target and its inhibition is potently anti proliferative to cancer cells However recent data suggests that there are two major disadvantages of the conventional approach to blocking the kinase activity of PLK First both general kinome ...
STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health -
Non-ATP competitive inhibitors of cyclin dependent kinases as cancer therapeutics
SBC: PPI PHARMACEUTICALS, LLC Topic: NCIDESCRIPTION (provided by applicant): As cancer is one of the leading causes of death in the United States with some sub-types remaining essentially untreatable, expansion of available drug targets will provide significant new options for the development ofmore effective antineoplastic agents. The major goal of this project is to apply a unique drug discovery strategy to cancer drug development. Th ...
STTR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health -
Point of Care Imaging for Cardiovascular Monitoring Light Energy Tissue Interactions
SBC: RFPi, Inc. Topic: NHLBIA research team of clinical medicine optical physics mechanical and electrical engineering disciplines at ECU has invented a new biomedical imaging technology Multi Spectral Physiologic Visualization MSPV MSPV is a proprietary laser illuminated hardware software imaging system that is non contact cm imaging distance non invasive no dyes or injections non ionizing no X ray CT an ...
STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health -
A Novel Hernia Mesh to Improve Anchor Point Fixation and Prevent Hernia Formation
SBC: Deep Blue Medical Advances, Inc. Topic: 300Abstract Two million laparotomies are performed annually in the U S with ventral hernia being a frequent complication in of patients The average cost patient for each hernia operation in the U S in was $ which amounts to $ billion annually The ten year ventral hernia recurrence rate is There are $ B in hernia meshes sold annually in the United States With ...
STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health -
Development of a New Carbohydrate based Anticoagulant Drug
SBC: GLYCAN THERAPEUTICS CORPORATION Topic: NHLBILow molecular weight heparins LMWHs a commonly used anticoagulant drug in the hospitals are carbohydrate based molecules Heparin is isolated from porcine intestine through a long and unreliable supply chain LMWH is a depolymerized product of heparin A worldwide distribution of contaminated heparin in impacting the purity and safety of LMWHs was associated with deaths in the US Th ...
STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health -
Geriatric Symptom Protocols for Improved Triage in Offices and Assisted Living
SBC: KEONA HEALTH, INC. Topic: NINRDESCRIPTION (provided by applicant): For medical practices, a major challenge is managing the hundreds of telephone calls received daily, many of which are about new or worsening medical symptoms. Particularly difficult are calls from persons with little or no medical training about frail older persons living at home or in assisted living (AL) communities. Incoming calls are typically answered by ...
STTR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health -
Development of fluorescence-based receptor binding assays for the detection
SBC: SEATOX RESEARCH INC Topic: NIEHSDESCRIPTION (provided by applicant): Harmful algal blooms (HABs) are becoming frequent occurrences off the coasts of the United States, particularly in coastal waters of New England, the Gulf of Mexico, and the Pacific Ocean. Historically, HABs have beenassociated with fish kills and marine mammal mortalities; however, their effects on human health and economic loss due to HAB contamination of se ...
STTR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health -
Creation of animal models of mitochondrial DNA disease for translational research applications
SBC: ENZERNA BIOSCIENCES LLC Topic: 400Mitochondria are the principal generators of cellular ATP by oxidative phosphorylation which links electron transport via Complexes I through IV to production of ATP via ATP synthase Over pathogenic human mitochondrial DNA mtDNA mutations associated with diseases ranging from cardiomyopathy to juvenile blindness have been identified Collectively millions are affected by mtDNA disease fo ...
STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health -
AML MutationCounter a tool to detect residual and recurrent leukemia
SBC: Asystbio Laboratories, LLC Topic: 102Abstract AsystBio LLC proposes to market a molecular tool kit called AML MutationCounter to count somatic mutations in genes that contribute to the development of acute myeloid leukemia AML We have developed a set of reagents and computer programs for application of next generation sequencing to count AML gene mutations The tool kit is versatile and can be used with either of the two major DNA ...
STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health -
Functional-selection of affinity reagents against DNA-protein complexes using targeted chromatin sequences
SBC: AXIOMX INC Topic: NIDDKDESCRIPTION (provided by applicant): Site-specific binding of proteins to DNA plays an important role in cell development, cell signaling, the cell cycle, and diseases such as cancer. There are two overarching goals to this proposal: (1) to develop a meansfor the identification of proteins bound to specific DNA sequences, and (2) to develop a better method for the identification of immunoprecipita ...
STTR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health