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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. High Frequency Dielectric Sensing Cardiac Radio Frequency Ablation Monitoring and Lesion Assessment System

    SBC: SIGT, LLC            Topic: NHLBI

    Atrial fibrillationAFibaffects aboutmillion individuals in the USA and is a significant cause of morbidity and mortalityPercutaneous catheter intracardiac Radio Frequency AblationRFAtreatment of AFib requires contiguous transmural lesions between anatomical boundaries for effective durable electrical isolationCurrent procedures have arecurrence rateprobably due to incomplete ablations and carry ar ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  2. Development of a cross-protective HRV vaccine

    SBC: BIOLOGICAL MIMETICS, INC.            Topic: NIAID

    ABSTRACTHuman rhinovirusesHRVare the leading cause of common colds and virus induced exacerbation of asthma and chronic pulmonary diseasesIn additionHRV can cause severe lower respiratory tract infections in childrenthe elderlyand immune compromised patientsThe economic burden of HRV is estimated to be at least $B each year in the US in terms of direct medical expenses and lost work and productivi ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  3. A Novel Chemokine Receptor Antagonist to Block Opioid Reinforcement, Relapse and Physical Dependence

    SBC: CREATIVE BIO-PEPTIDES INC            Topic: NIDA

    Project Summary Abstract This SBIR application is proposed in response to RFA DAthe HEAL Initiative on building technologies to stop the opioid crisisCreative Bio PeptidesIncis committed to providing effective and safe non opioid treatments for themillion Americans suffering daily pain and themillion who live with opioid dependency or addictionCurrent decades old addiction treatments like methadon ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  4. An Efficient System for 30-K MAS-NMR-DNP for Macromolecule Structure Determinations

    SBC: DOTY SCIENTIFIC, INC.            Topic: 400

    The critical importance of solid state NMRssNMRwas recently demonstrated byafter nearly two decades of intense effortsyielding the first atomic resolution structures of the Aand Aamyloid fibrils that play acrucial role in Alzheimer s DiseaseADKey to that advance is a technique denoted as dynamic nuclearpolarizationDNPwith magic angle spinningMASFor technical reasonsdiscussed belowthese experiments ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  5. Using Interactive Digital Media to Teach Cardiopulmonary Resuscitation to High School Students

    SBC: CORAM TECHNOLOGIES, INC.            Topic: 400

    Summary Abstract Out of hospital cardiac arrest affects overpeople in the U Sannuallybut onlysurviveBystander cardiopulmonary resuscitationCPRimproves survivalbut rates of training in the U Sare lowIt is recently required by law inU Sstates that high school students learn CPRHoweverthere is great variability nationwide in howby whomand when students are taughtAdditionallycurrent methods of teachin ...

    STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  6. An in vitro diagnostic assay for the early and accurate detection of platelet-activating antibodies associated with Heparin-induced Thrombocytopenia

    SBC: RETHAM TECHNOLOGIES LLC            Topic: NHLBI

    PROJECT SUMMARY ABSTRACT This SBIR proposal is aimed at demonstrating feasibility of developing a technically simple and highly accurate in vitro diagnosticIVDassay for Heparin induced thrombocytopeniaHITa serious complication of heparin treatmentThe proposed assay is based on recent findings that Platelet FactorPFtreated platelets can be used for the sensitive and specific detection of clinically ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  7. Ice-free vitrification and nano warming technology for banking of cardiovascular structures.

    SBC: TISSUE TESTING TECHNOLOGIES LLC            Topic: NHLBI

    ABSTRACT This proposal focuses on translation of ice free cryopreservation by vitrification employing a novel approach of volumetric heating by nanowarming using Fe nanoparticles in an alternating electromagneticeldVitrificationsub zero storage below the glass transition temperature in aglassyrather than a crystalline frozen phaseis a form of cryopreservation that avoids ice formationVitri cation ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  8. Mobile Peer Support for Opioid Use Disorders: Refinement of an Innovative Machine Learning Tool

    SBC: BEACON TECH INC            Topic: R41

    PROJECT SUMMARY This proposal develops a novelartificial intelligenceAIenabledmobile treatment delivery method that fulfills the need for a robustsecuretechnology based peer support platform to support patients with opioid use disordersOUDsThe majority of individuals with OUDs in the United States do not receive any formal substance use treatmentand growing evidence suggests that many OUD patients ...

    STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  9. SBIR Phase I: Affinity membrane for rapid, high-recovery purification of gene therapy viral vectors

    SBC: Purilogics, LLC            Topic: 400

    Project Summary This SBIR Phase I project will address the need for a product that can dramatically increase the recovery and purification speed for viral vectors used in gene therapySeven thousand rare diseases that have few or no treatment options are affectingof the US populationAlthough gene therapies are promising for the treatment of many rare diseasesmost are at an early stage of developmen ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  10. Broad Spectrum Thermostable Single dose Papillomavirus-like Particles (VLP) for the prevention of all HPV-associated cancers.

    SBC: PATHOVAX LLC            Topic: 100

    Project Summary The goal of PathoVax s SBIR Phaseproject is to further develop the potential and global applicability of RGVaxTMa broad spectrum universal HPV vaccineRGVaxTM is currently a single chimeric HPV virus like particleVLPplatform that displayscopies of the highly conservedneutralizing HPV epitopeRGAnimal vaccination studies confirmed broad spectrum protectionvia RGcross neutralizing anti ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
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