Award Data

GeneCapture, Inc. is proposing to develop a rapid in vitro diagnostic prototype using our patented molecular-based CAPTURE (ConfirmActive Pathogens Through Unamplified RNA Expression) assay. Based on the results and experience gained in our Phase I STTR contractHDTRA1-16C-0061: Infectious Disease Diagnostics and Differentiation of Viral vs. Bacterial Infections for Point of Care Applications, we p ...

Establish a radiation-aware analysis capability in a commercial EDA design flow that will enable first-pass success in radiation-hardened by design (RHBD) for DoD ASICs in much the same way that existing EDA design suites ensure first pass functionality and performance success of complex ASICs destined for commercial applications. Layout-aware, calibrated single-event radiation models that captur ...

Near-field scanning optical microscopy (NSOM) is a powerful and unique approach to characterize the chemical, physical and potentially biochemical properties of materials with the nanometer scale resolution in real-time. A key element for NSOM systems that combine optical spectroscopy with scanning probe microscopy, is the actual probe itself. While many commercial vendors offer off-the-shelf meta ...

Graphene nanomaterials offers multiple technical benefits in printed electronics, structural materials, displays, capacitors, high-performance computing applications, and especially energy storage where researchers have reported a five-fold increase in the charge rate of a graphene- enhanced Li-ion battery. Historically, industrial production of graphene nanomaterials has been hindered by the need ...

There are currently no vaccines or therapeutics available for Marburg Virus Disease (MVD). Given the specter of weaponization and the terriblemorbidity and high mortality rate of MVD, this represents a critical threat to the operational readiness of the Warfighter. While traditionalvaccines have proven to be a huge contribution to public health, they do have some limitations especially in the cont ...

Flow Pharma, Inc. is a biotechnology company in the San Francisco Bay Area developing fully synthetic cytotoxic T lymphocyte (CTL)stimulating peptide vaccines for Marburg virus. The FlowVax vaccine platform allows us to create dry powder formulations of biodegradablemicrospheres and TLR adjuvants incorporating class I and class II T cell epitopes. FlowVax vaccines can be designed for delivery by i ...

With 27% of the world’s coal reserves located in the United States, development of a clean, efficient, and economically viable pathway to coal utilization is of strategic importance. Development of advanced coal-to-liquids technologies provides this direct pathway, while improving energy security, reducing coal environmental footprint, and promoting economic development directly in the communiti ...

Renewable sources of energy including solar and wind are fast gaining ground on fossil fuels, in part because of their sustainability and environmental benefits. A major issue, however, has been finding efficient ways to store the energy that renewables generate for use when the demand for energy is high. Lithium-­‐sulfur batteries, which store electrical energy by transferring electrons to or ...

For effective protection against EMP and HPM threats, it is important to understand the physics of the threats, and also to quantify the effects they have on electrical systems. EMP and HPM vulnerability testing requires delivery of high peak power and electric fields to distant targets. The most practical solution to simulate such environments is to develop a modular, optically-isolated MV-antenn ...

Metal photoinjector cathode development has shown recent promise with nano-patterning technology. However, in order to be competitive with semi-conductor cathodes, a further enhancement in efficiency is needed. TECHNICAL APPROACH Specific nano-patterning of sub-wavelength features to produce antennae provides coupling of incoming laser light with the surface of the metal cathode. Bowtie nano-anten ...