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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Epigenetic Markers and Sustained Cytoprotection for Stroke Treatment

    SBC: ZYMO RESEARCH CORP.            Topic: 101

    PROJECT SUMMARY ABSTRACT Stroke injury is a process that occurs over a long duration with pathologic changes that result in long term neurologic dysfunction For stroke there exists an important need for a strategy that can provide safe and efficacious stabilization to the hypoperfused brain and initialize long lasting endogenous neuroprotection for prevention of long term neurologic dysfunction ...

    STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  2. Gold nanoparticle laser warming of cryopreserved zebrafish embryos

    SBC: NANOCOMPOSIX, INC.            Topic: OD

    Project Summary Abstract In the past decade laboratories around the world have produced tens of thousands of mutant transgenic and wild type zebrafish lines for a wide range of genetic and biomedical research Maintaining all of these valuable genotypes is expensive risky and beyond the capacity of even the largest stock centers Cryopreservation of zebrafish sperm eggs and embryos is vital ...

    STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  3. Hit to Lead optimization of small molecule inhibitors of herpes simplex viruses

    SBC: CASTERBRIDGE PHARMACEUTICALS INC            Topic: R

    Herpes simplex viruses and HSV HSV cause a wide range of significant diseases including oral genital lesions corneal blindness and encephalitis HSV and HSV are both transmitted sexually and can infect babies during birth Therapy for HSV relies primarily on nucleoside analogs such as acyclovir ACV which are insufficiently effective and resistant viruses are becoming common amo ...

    STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  4. I- Corps Administrative Supplement to Novel Reagents for Breast Tumor SPECT Imaging R41CA217546

    SBC: Cavatar LLC            Topic: NCI

    PROJECT SUMMARY Early cancer detection and diagnosis are critical for patient survival and treatment successFor the imaging of breast and other solid tumorsthe diagnostic power of advanced imaging techniques such as SPECT could benefit tremendously from improved contrast agents that rapidly and selectively accumulate in tumor lesions and produce high tumor to background signal ratiosWe are develop ...

    STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  5. Integrated Platform for Mass Spectrometric Studies of Protein Structure

    SBC: PROTEIN METRICS INC            Topic: 100

    Summary Technology for studying the higher order structure HOS of biomolecules encompasses some of the most important tools in all of science and is a highlighted NIGMS research topic Mass spectrometric methods for studying HOS include oxidative footprinting and other methods to covalently label amino acid side chain functional groups and also hydrogen deuterium exchange HDX on protein bac ...

    STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  6. Integrated tools for higher order structure determination by cross link analysis

    SBC: PROTEIN METRICS INC            Topic: 100

    Summary The use of mass spectrometry MS for quantitative protein characterization has increased dramatically identifying and quantifying thousands of proteins is no longer a heroic task nor is characterizing therapeutic proteins in detail Due to widely available software quantitative mass spectrometry has become routine and widely used for addressing questions in basic biology translational ...

    STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  7. MISSION U A Multimedia Training Tool for Treating Individuals with Co occurring Mental Health and Substance Use Disorders

    SBC: PRAXIS, INC.            Topic: 350

    Millions of U S adults suffer from a co occurring mental health and substance use disorder COD A COD is often difficult for providers to address and thus clients may experience poor treatment engagement symptom exacerbations homelessness incarceration and often utilize acute and emergency services increasing medical expenditures Currently the healthcare delivery system needs but does ...

    STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  8. My MESSAGE Improving Wayfinding and Reducing Challenging Behaviors in Persons with Dementia Through the Use of RFID Technology

    SBC: HEARTHSTONE ALZHEIMER CARE LTD.            Topic: NIA

    In the proposed study we will develop and evaluate a product called My MESSAGE Multimedia Ecopsychosocial Support System for Alzheimer s within Geriatric Environments which will circumvent the limitations of traditional visual cues and also provide unprecedented flexibility and precision for assisting with wayfinding and reducing other challenging behaviors in PWD The target consumer for MM w ...

    STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  9. Neuro Optical Diagnostic System for Macular Degeneration

    SBC: NEUROFIELDZ INC.            Topic: NIA

    Age related macular degeneration AMD causes progressive loss of central vision and is the leading cause of blindness in the developed world A major challenge in the development of effective treatments for AMD is the lack of sensitive practical visual function endpoints People with AMD manifest delayed dark adaptation DA recovery and DA tests are a FDA approved method for diagnosing AMD Cu ...

    STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  10. Next Generation Regenerative Therapy with Pim Enhanced Cardiac Progenitor Cells

    SBC: CardioCreate, Inc.            Topic: NHLBI

    PROJECT SUMMARY Myocardial regenerative therapy is poised to revolutionize the way heart failure is treated but further improvements and enhanced products are needed to make this therapy truly safe and efficacious Our company CardioCreate Inc has pioneered the use of genetic engineering to enhance the regenerative potential of human Cardiac Progenitor Cells CPCs intended for autologous the ...

    STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
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