Award Data

The broader impact/commercial potential of this Small Business Technology Transfer (STTR) Phase I project will provide the market with a novel non-invasive method for measuring fluid status in patients with congestive heart failure (CHF). The ability to detect volume status changes prior to the onset of heart failure symptoms has tremendous patient care and economic impact. According to the Americ ...

The broader impact/commercial potential of this Small Business Technology Transfer (STTR) Phase I project will be to develop odorant receptor function bioassays to provide services for companies that develop and formulate odors used in many kinds of commercial products. These services identify the biological sensors responsible for specific odor sensations and determine how these sensors are invol ...

The broader impact/commercial potential of this Small Business Innovation Research (SBIR) Phase I project is to reduce the cost of RF hardware, enabling wider adoption of new generations of mobile devices and services for Internet of Things applications. The project has the potential to help transform a number of sectors, including medicine and healthcare monitoring and diagnostics, transportation ...

The broader impact/commercial potential of this Small Business Technology Transfer (STTR) Phase I project is to mitigate fall risk among Parkinson's patients and the elderly, which will potentially save families and patients $34 billion annually in fall-related injuries and rehabilitation. Falling is common among individuals age 65 and over, one in three people fall at least once in a calendar yea ...

The broader impact/commercial potential of this Small Business Technology Transfer (STTR) Phase I project will be to develop reliable technology for the production of aptamer pairs. Aptamers are core reagents in emerging markets, regarded as alternatives to monoclonal antibodies in therapeutics, diagnostics, and imaging. They possess several appealing qualities: Ease of in vitro synthesis, flexibl ...

Objectives and Intellectual Merit: The infrastructure of modern civilization is a set of complex systems1 that dynamically interact across multiple layers of abstraction. Researchers from many disciplines2 are designing analytical tools for predicting the global and local behaviors of these complicated, multi-layer networks. Easily usable, available (open source) and inter-operated tools are neede ...

Terrorist use of radioactive nuclear materials via nuclear and/or radiological dispersion devices (dirty bombs) is a serious threat. Therefore, it is critical to detect the proliferation of nuclear material. Critical challenges facing this objective include: (a) high sensitivity detection of signature emissions (e.g., gamma rays) from common radioactive isotopes behind shielding, and (b) cost-effe ...

The broader/commercial impact of the Small Business Technology Transfer (STTR) Phase II project will be a cell sorter, a new research tool for life science research, animal reproduction, and cell-based therapy. In the past decade, cell sorters have become vital in many fields, such as molecular and cellular biology, immunology, plant biology, animal reproduction, and medical diagnostics and therap ...

This Small Business Technology Transfer (STTR) Phase I project is aimed at the development of improved instrumentation for analytical chemistry, via the production of novel and improved phases for high-pressure and ultra-high-pressure liquid chromatography (HPLC/UHPLC). This effort will develop a synthetic route to diverse surface chemistries built on an underlying phase based on known polymer che ...

The broader impact/commercial potential of this Small Business Technology Transfer (STTR) Phase I project is to shift current practices in bone fracture fixation care from using permanent metal implants to biodegradable metal implants (screws, plates, pins, rods, etc.). A promising biodegradable metal that is gaining widespread attention is magnesium. This project will advance magnesium implant te ...