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The Award database is continually updated throughout the year. As a result, data for FY23 is not expected to be complete until September, 2024.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Bio-Effects of Ultra-High MRI Gradient Slew Rates

    SBC: WEINBERG MEDICAL PHYSICS, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): The spatial resolution and acquisition times for magnetic resonance imaging and spectroscopy could be improved through the application of more powerful and rapid magnetic gradients, thereby potentially leading to improved cardiac imaging and delineation and detection of cancers. Unfortunately, gradient field strength is limited by concerns about potential neura ...

    STTR Phase II 2008 Department of Health and Human ServicesNational Institutes of Health
  2. Hyperspectral Assessment & Prediction of Diabetic Foot U

    SBC: Hypermed, Inc.            Topic: N/A

    DESCRIPTION (provided by applicant): Foot disease complications seriously impact lives of people with Type 1 diabetes. A quantitative method to evaluate efficacy of therapy, or better, to define tissue at risk & prevent initial ulcer formation would be highly beneficial. HYPERMED'S long-term objective is to reduce frequency of foot ulcers & amputation by developing Foot HyperSpectral Imaging (FHSI ...

    STTR Phase II 2005 Department of Health and Human ServicesNational Institutes of Health
  3. Novel commensal polysaccharide treats multiple sclerosis through Treg modulation

    SBC: SYMBIOTIX BIOTHERAPIES, INC.            Topic: NIAID

    DESCRIPTION provided by applicant Multiple sclerosis MS is a chronic demyelinating inflammatory disease that is the most common neurological disease of young adults affecting over patients in the US and over million patients worldwide MS is a disease of high unmet medical need currently treatable with one of twelve FDA approved drugs all of which result in either significant i ...

    STTR Phase II 2015 Department of Health and Human ServicesNational Institutes of Health
  4. VALIDATION AND QUANTIFICATION OF FFPE ANTIGEN RETRIEVAL BY PROTEOME ANALYSIS

    SBC: CALIBRANT BIOSYSTEMS, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Because of the long history of the use of formalin as the standard fixative for tissue processing in histopathology, there are a large number of archival formalin-fixed and paraffin-embedded (FFPE) tissue banks worldwid e. These FFPE tissue collections, with attached clinical and outcome information, present invaluable resources for conducting retrospective pro ...

    STTR Phase II 2008 Department of Health and Human ServicesNational Institutes of Health
  5. Development and testing of a behavioral activation mobile therapy for elevated depressivesymptoms

    SBC: MOUNTAINPASS TECHNOLOGY LLC            Topic: 104

    PROJECT SUMMARY/ABSTRACT Depression is the leading cause of disability worldwide, with more than 300 million people affected. Most adults with depressive symptoms make at least one annual visit to a primary care physician (PCP). As such, primary care offers a ripe opportunity to identify and treat adults with depressive symptomatology. Yet, depression has historically been undertreated in primary ...

    STTR Phase II 2020 Department of Health and Human ServicesNational Institutes of Health
  6. Using Rendever to improve the quality of life of older adults with cognitive impairments in senior living communities and their family members who live at a distance.

    SBC: RENDEVER, INC.            Topic: NIA

    ABSTRACTThe United States is experiencing a public health crisis on a massive scale due to the number of people with dementia, lack of cures, and challenges associated with caregiving for this population.1,2 until cures for the dementias are discovered, new technologies and interventions are imperative that can reduce the stress and emotional burden of Alzheimer’s disease (AD) and Alzheimer’s ...

    STTR Phase II 2021 Department of Health and Human ServicesNational Institutes of Health
  7. CG-GRID: Computational Genetics Grid Resource for Interaction Discovery

    SBC: PARABON COMPUTATION, INC.            Topic: 400

    DESCRIPTION provided by applicant Advances in DNA sequencing technology have now made it practical and affordable to generate datasets containing millions of genetic attributes that can be tested for association with disease susceptibility The computational complexity of searching for genetic interactions over such high dimensional datasets imposes great challenges for genome wide associatio ...

    STTR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health
  8. High Resolution Digital Imaging X-ray Detectors

    SBC: Aguila Technologies, Inc.            Topic: N/A

    DESCRIPTION (provided by applicant): The aim is to develop a high resolution, high contrast detector for digital x-ray imaging systems. The target detector would have a Detective Quantum Efficiency much greater than 80%, a limiting resolution of at least 10 lp/mm, ultra-low noise, linear response and a dynamic range of more than 14 bits. The proposal is to build such a detector by using CdZnTe c ...

    STTR Phase II 2005 Department of Health and Human ServicesNational Institutes of Health
  9. Development of a low-cost hardware accelerator for 3D image registration

    SBC: IGI TECHNOLOGIES, INC            Topic: 102

    DESCRIPTION provided by applicant Our overall goal is to develop a novel computing solution for automatic and accurate registration spatial alignment of dimensional D medical images of any modality and any anatomy rigid or deformable in minute or less Such capability currently does not exist Existing image registration solutions have limited accuracy and or limited applicability p ...

    STTR Phase II 2011 Department of Health and Human ServicesNational Institutes of Health
  10. INEXPENSIVE INTERACTIVE MOLECULAR MODELING SOFTWARE

    SBC: VERACHEM LLC            Topic: N/A

    Today, promising new protein targets for small molecule drugs are being discovered rapid. With increasing frequency, the 3D structures of these proteins are available or can be modeled from known protein structures. Demand is therefor growing for software to support structure-based discovery of protein ligands as candidate drugs. However, existing software leaves enormous room for improvement in a ...

    STTR Phase II 2002 Department of Health and Human ServicesNational Institutes of Health
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