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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. A digital tool for monitoring speech decline in ALS

    SBC: MODALITY.AI , INC            Topic: NIDCD

    PROJECT SUMMARY Amyotrophic Lateral Sclerosis (ALS) is a fatal neurodegenerative disease resulting in the progressive loss of limb, trunk, and head and neck (bulbar) motor function and is the most common adult-onset motor neuron disease. The disease is characterized by significant across-patient heterogeneity in the onset region and in pattern and progression rate, making early and accurate diagno ...

    STTR Phase II 2023 Department of Health and Human ServicesNational Institutes of Health
  2. A 3-D Interactive Atlas of the Human Skull

    SBC: BROWN AND HERBRANSON IMAGING            Topic: N/A

    DESCRIPTION (provided by applicant): Broad long term objectives and specific aims: The long-term objective of this project is to develop a digital anatomical research resource library of very high-resolution computational models, and imaging data sets. Our objective is to produce an anatomical library otf the complete human skeleton. The implications of this project, both scientific and social are ...

    STTR Phase I 2006 Department of Health and Human ServicesNational Institutes of Health
  3. A 3-D Interactive Atlas of the Human Skull

    SBC: BROWN AND HERBRANSON IMAGING            Topic: N/A

    DESCRIPTION (provided by applicant): The principal aim of this project is to develop a resource library of very high-resolution computer models and imaging data sets of human skulls. This skull database project, which builds upon and is an extension of the Tooth Atlas project, will be the first phase of a complete, whole body, osteology library. As the imaging and computer technology advances, th ...

    STTR Phase II 2009 Department of Health and Human ServicesNational Institutes of Health
  4. Administrative Supplement to restore fee funds

    SBC: AMERICAN LIFE SCIENCE PHARMACEUTICALS, INC.            Topic: NINDS

    Project Summary Traumatic brain injuryTBIcauses detrimental behavioral dysfunctions and brain neurodegeneration butunfortunatelythere currently is no effective pharmaceutical TBI treatmentThe underlying PhaseSTTR grant is to develop a new class of TBI drugs that inhibit the protease cathepsin BGenetically deleting the cathepsin B gene in mice results in substantial behavioral and pathology improve ...

    STTR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  5. A dual histone deacetylase and glycogen synthase kinase 3 beta inhibitor for treating pancreatic adenocarcinoma

    SBC: Avenzoar Pharmaceuticals, Inc.            Topic: 102

    ABSTRACT Pancreatic cancer is a disease with no effective treatmentIt s low five year survival rateestimated at betweenandranks it the fourth highest of cancer related of death in the U Sdespite being the twelfth most common type of cancerEach year in the U Sthere are nearlynew cases and more thandeaths caused by the diseaseBypancreatic cancer is expected to be the second most common cancer relate ...

    STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  6. A dual-polarized Doppler Radar system for fall detection in an indoor environment

    SBC: MS Technologies Corporation            Topic: NIA

    DESCRIPTION provided by applicant Falls are a leading cause of injuries and deaths among older adults OAs and will be an increasing public health concern given projections of future increases in the number of OAs in the US Fall detection and or surveillance systems are needed to enhance an OAandapos s confidence and independence and to facilitate rapid post fall responses This project wil ...

    STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health
  7. Advanced Assessment to Accelerate Diagnostic Skill Acquisition

    SBC: Parallel Consulting, LLC            Topic: NIGMS

    DESCRIPTION (provided by applicant): Current approaches to medical education produce new physicians with insufficient clinical competency to practice effectively with limited supervision, which has serious implications for patient outcomes during hospitaloff hours. Up to 70% of patients admitted to a hospital are admitted on nights or weekends, when staffing is low and residents may be in charge o ...

    STTR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  8. Advanced Assessment to Accelerate Diagnostic Skill Acquisition, Phase II

    SBC: Parallel Consulting, LLC            Topic: 300

    Project Summary Today s clinical learning environments do not provide the level of deliberate practicedirect supervisionand rigorous assessment and feedback needed to develop diagnostic reasoning expertiseClinical performance assessment emphasizes learner evaluation over learner developmentlacks rigor and utility for developmental purposesand clinical teachers have expressed particular difficulty ...

    STTR Phase II 2017 Department of Health and Human ServicesNational Institutes of Health
  9. Advanced Detection Technologies for Biochips

    SBC: INDEVR, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): The long-term objective of the proposed work is the development of innovative detection technologies for biochips (a.k.a. DNA microarrays). It is envisioned that the proposed technologies will enable the application of biochips to biodefense, particularly when a rapid and reliable diagnostic screen is required in the field. The Specific Aims of the proposed wo ...

    STTR Phase I 2004 Department of Health and Human ServicesNational Institutes of Health
  10. Advanced optics to unlock large field-of-view multiphoton imaging for neuroscience and beyond

    SBC: PACIFICOPTICA LLC            Topic: 101

    Project summary Currently available optical components limit biomedical imaging. In particular, in neurobiology, standard microscope components limit the field-of-view and speed of imaging of neuronal activity. Through prior work on BRAIN Initiative project, we have developed approaches for new optical components that expand the field-of-view 5 to 50 times over standard microscopes, with no loss i ...

    STTR Phase I 2023 Department of Health and Human ServicesNational Institutes of Health
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