Award Data

The recent advances of modern high-throughput genomic technologies have resulted in a large number of fully sequenced microbial organisms. The construction of these comprehensive metabolic models serves many purposes including encapsulating all the data and allowing for in silco experiments to be performed that can drive experimental work and aid in strain development and optimization. The creatio ...

Rapid detection and identification of chemical warfare nerve agents (CWNAs) are critical to the screening and subsequent treatment of exposed warfighters. Inhibition of cholinesterase activity is insufficient as a marker of exposure to CWNAs, in that it can give misleading results and does not distinguish CWNAs from commonly employed pesticides. This proposal presents a revolutionary field-porta ...

The goal of this Phase II project is to develop an automated detector system for real-time detection of aerosolized biowarfare agents. Our proposed detection system utilizes Fourier Transform Infrared (FTIR) spectroscopy as the agent identifier, where the main advantages of this approach are that it is reagentless, operates in complex air environments, and provides fast detection, high sensitivit ...

To reduce the amount of radioactive material in common use for commercial applications and thus improve public security, the DNDO is seeking replacements for devices that commonly incorporate such material. Physical Optics Corporation (POC) proposes to develop a new Dielectric Relaxation Analyzing Gauge (DRAG) that will replace isotope-based gauges for thickness, level, and velocity measurements i ...

We propose a Phase II project to develop and prototype a flexible time-domain terahertz (TD-THz) instrument that can be marketed to customers currently utilizing nuclear source gauges. While nuclear gauges are an established technology, their radiological sources present on-going safety, security, regulation, and disposal concerns. A primary goal of this project is to establish that; when all tech ...

This proposal is to respond Army CBD SBIR Phase II invitation for “Computer-Assisted Strain Construction and Development Engineering (CASCADE)”. Our approach is to apply a machine learning system together with publicly available data and private collaboration data for discovering the predictive relations between genomic fingerprints of an organism and its metabolic capabilities, and then use t ...

This Phase II effort will develop a functional prototype of DMnet, a distributed botnet detection and mitigation system. Our Team will develop and integrate state-of-the-art research in ontology, data fusion, data mining, and data warehousing into DMnet nodes. These nodes will be distributed throughout a network and will work together in a trusted grid to provide increased cyber awareness for botn ...

The Phase I tasks for optimized receiver development were successfully accomplished and point to a Phase II program with emphasis on detector and electronics development for the long wave infrared. Detector types to be further investigated and developed include the single chip photovoltaic HgCdTe, hybrid detector/preamplifier, and avalanche photodiode. Low noise preamplifiers with cooled component ...

To develop advanced ¿channel-to-droplet¿ sample extraction and purification functions on a compact cartridge that is free of sensitive and complex microfluidic components, Core Microsolutions (CMSS) and Professor Sung Cho of the University of Pittsburgh propose to integrate Electrowetting-on-Dielectric (EWOD) droplet handling and in-droplet concentration capabilities with well proven channel-bas ...

Intelligent Optical Systems (IOS) has developed and demonstrated a prototype dazzler that utilizes an array of super-bright Light Emitting Diode (LED) clusters to produce disorientation and strong flashblindness with afterimages. In this project, IOS proposes to develop a significantly improved device that can operate at distances up to 50 feet at the maximum permissible eye-safe level. Two new in ...