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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Broad-Spectrum Therapeutic Human Antibodies for Dengue Virus Infections

    SBC: L2 DIAGNOSTICS LLC            Topic: N/A

    DESCRIPTION (provided by applicant): The overall goal of this project is to develop antibody therapeutics to treat life-threatening flavivirus infections. Our working hypothesis is that antibodies recognizing specific, highly conserved envelope protein epitopes can prevent and treat infection by several different flaviviruses, including all four serotypes of dengue virus and West Nile virus (WNV). ...

    STTR Phase I 2006 Department of Health and Human ServicesNational Institutes of Health
  2. A HUMAN MONOCLONAL COCKTAIL FOR RSV IMMUNOTHERAPY

    SBC: MAPP BIOPHARMACEUTICAL, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): The central goal of this application is to develop a combination product comprising two fully human monoclonal antibodies (mAbs) produced in plants for the prevention of serious disease caused by respiratory syncytial virus (RSV). RSV causes high morbidity and mortality in certain neonate populations as well as in the elderly and in bone marrow transplant patie ...

    STTR Phase I 2006 Department of Health and Human ServicesNational Institutes of Health
  3. ROMP-Derived Oligomers for Faciliated Synthesis

    SBC: MATERIA, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): This Phase I Small Business Technology Transfer study between Materia, Inc. and the University of Kansas is focused on the development of high-load, oligomeric reagents and scavenging agents derived from ring-opening metathesis polymerization (ROMP), one of several core metathesis technologies at Materia, Inc. The specific aims during Phase I focus on three are ...

    STTR Phase I 2006 Department of Health and Human ServicesNational Institutes of Health
  4. Highly-Multiplexed Accurate HLA Typing using PAP and Digital Bead Technologies

    SBC: MAXWELL SENSORS INC.            Topic: N/A

    Highly-Multiplexed Accurate HLA Typing using PAP and Digital Bead Technologies

    STTR Phase I 2006 Department of Health and Human ServicesNational Institutes of Health
  5. Vapor-based Manufacturing Multifunctional Coatings

    SBC: MICHIGAN CRITICAL CARE CONSULTANTS, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): We propose a new manufacturing process for multifunctional coatings of biomedical implants. Towards this goal, polymer coatings applied by chemical vapor deposition (CVD) are exceptional candidates for the coating of implanted biomedical devices as indicated by their use in FDA approved drug-eluting stint (Cypher stint, J&J) uses a vapor-deposited polymer (pary ...

    STTR Phase I 2006 Department of Health and Human ServicesNational Institutes of Health
  6. Impeller optimization for a combined pump-oxygenator

    SBC: MICHIGAN CRITICAL CARE CONSULTANTS, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Lung disease is America's third largest cause of death. Adult respiratory distress syndrome (ARDS) afflicts approximately 150,000 patients every year in the US. Lung disease costs the American economy $148 billion yearly in total expenditures. While treatment for heart disease and cancer has been marked by a significant fall in their rates of death (36.6% for h ...

    STTR Phase I 2006 Department of Health and Human ServicesNational Institutes of Health
  7. Fluorescence lifetime method for guided therapy of brain tumors

    SBC: MICROSURGEON, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): We propose clinical evaluation and optimization studies of time-resolved fluorescence spectroscopy (TR-LIFS) technique for the intraoperative identification of tumor vs. normal brain during neurosurgical resection of brain tumors. A critical need currently for neurosurgeons operating on infiltrative glial neoplasms is the ability to distinguish between normal ...

    STTR Phase I 2006 Department of Health and Human ServicesNational Institutes of Health
  8. Pre-clinical Feasibility Study of Tissue Oxygenation Imager

    SBC: Modulated Imaging Inc.            Topic: N/A

    DESCRIPTION (provided by applicant): Chronic wounds are non-healing wounds such as diabetic ulcers and pressure ulcers. Each year, 6.5 million cases occur in the U.S., costing the economy billions of dollars. Cost-effective and efficient management of chronic wounds depends on quick assessment and diagnosis of the underlying reasons for compromised healing. Ischemia is one of the main complication ...

    STTR Phase I 2006 Department of Health and Human ServicesNational Institutes of Health
  9. Laboratory mouse identification and inventory control

    SBC: MUSE TECHNOLOGIES, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Project Summary: The laboratory mouse is an essential experimental resource for modern biomedical research. Scientists currently use hundreds of varieties and strains of mice, and generate over 10 million individual animals each year. Tens of millions of dollars of NIH funding annually support mouse model research, with millions directly allocated to the mainte ...

    STTR Phase I 2006 Department of Health and Human ServicesNational Institutes of Health
  10. NANOTEMPLATE ENGINEERING OF A STEALTH MRI CONTRAST AGENT

    SBC: NANOMED PHARMACEUTICALS, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): The increasing costs of therapy and the demonstrated benefits of improved treatment efficacy with early detection are important incentives to develop tumor diagnostic agents of greater specificity and sensitivity. Paramagnetic gadolinium complexes are widely used as MRI (magnetic resonance imaging) contrast agents to improve sensitivity and/or specificity duri ...

    STTR Phase I 2006 Department of Health and Human ServicesNational Institutes of Health
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