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The Award database is continually updated throughout the year. As a result, data for FY23 is not expected to be complete until September, 2024.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Sonomyographic Control of Fiber-Optically Sensorized Prosthetic Fingers for Graded Force Actuation

    SBC: INTELLIGENT FIBER OPTIC SYSTEMS CORP            Topic: NINDS

    Sonomyographic Control of Fiber Optically Sensorized Prosthetic Fingers for Graded Force Actuation Intelligent Fiber Optic Systems CorporationIFOSCalle del MundoSanta ClaraCAwww ifos com PROJECT SUMMARY ABSTRACTMAXIMUMLINESIn this Phase I SBIR applicationIFOS and George Mason UniversityGMUpropose an innovative control system leveraging on two emerging technologiesultrasonic imaging based readout o ...

    STTR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  2. Portable Liquid Chromatograph for Point-of-Care Monitoring of Illicit Substances

    SBC: AXCEND LLC            Topic: R41

    Project Summary Abstract Point of carePOCtesting of clinical samples for the presence of illegal substances and their metabolites is important for monitoring substance use disordersemployment screeningand legal matters relating to drug abstinenceTypical immunoassay screening methods suffer from higher false testing rates and do not provide quantitative informationConfirmatory tests that are used f ...

    STTR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  3. Therapeutic Inhibition of BCL6 in Systemic Lupus Erythematosus

    SBC: L2 DIAGNOSTICS LLC            Topic: NIAMS

    ABSTRACT Systemic autoimmune diseases such as rheumatoid arthritis and systemic lupus erythematosus are characterized by polyclonal T cell activation driving the production of pathogenic class switched autoantibodiesThe class switchedsomatically mutated antibodies are generated from germinal centerGCB cellsA subset of effector CDT cellsknown as T follicular helperTfhcellshas been shown to play an ...

    STTR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  4. A Novel Therapeutic that Harnesses Microtubules to Promote Cavernous Nerve Regeneration after Radical Prostatectomy

    SBC: MICROCURES INC            Topic: 300

    Radical prostatectomyRPis a commonly used treatment option for localized prostate cancerUnfortunatelythe procedure carries a risk of post surgical complications including a high risk of erectile dysfunctionEDAccording to The Prostate Cancer Outcomes Studyvirtually all men experience ED after surgeryincluding a profound loss of nocturnal erectionsThe Prostate Cancer Outcomes Study further reveals t ...

    STTR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  5. Regulation of Autoimmune Type 1 Diabetes by Serpins B1 and A1 (Alpha 1-Antitrypsin)

    SBC: SERPLUS TECHNOLOGY LLC            Topic: 200

    The number of people with diabetes worldwide is predicted to increase frommillion intomillion inThe health care costs of treating the disease account forof the global health expenditure and continue to be a huge economic burdenIDF World AtlasTypediabetes mellitusT DMconstitutesof the disease burdenIt is an autoimmune diseasethought to be triggered by genetic or environmental factors in early child ...

    STTR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  6. Developing an efficient E-cigarette aerosol generation and exposure system for rodent models with aerosol characteristics equivalent to those inhaled by E-cigarette users

    SBC: AUTOMATE SCIENTIFIC, INC.            Topic: NIDA

    Abstract E cigaretteE ciguse has rapidly proliferated worldwideIt is speculated that E cig use may exceed conventional cigarette use withinyearsCigarette smoking is the leading preventable cause of death and disabilityAs E cigs are a relatively new productstudies are needed to determine their long term detrimental effectssome of which may be similar to the long term detrimental effects of nicotine ...

    STTR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  7. The Kappa Partial Agonist PPL-103 as a Potential Cocaine Abuse Pharmacotherapy

    SBC: PHOENIX PHARMALABS, INC.            Topic: NIDA

    Abstract Currentlyclinically used drug abuse medications exist for treatment of addiction to opiatesalcoholand nicotinebut not cocaineThe objective of the proposed project is to test the hypothesis that the partial kappa agonist PPLcan be effective as a pharmacotherapy for treatment of cocaine abuseBecause of chronic drug induced changes in the kappa opioid receptor systemkappa receptor directed c ...

    STTR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  8. Discovery of novel CDK4/6-PI3K-BRD4 inhibitor SRX3177 for augmented anti-cancer activity

    SBC: SignalRx Pharmaceuticals Inc.            Topic: 102

    Three CDKinhibitors were recently approved to treat breast cancerBrCAin combination regimentsDespite significant clinical activitytreatment of BrCA patients with these combinations does not result in a durable responseHencethere is an unmet medical need to develop targeted therapeutic agents which will augment the activity of CDKinhibitors in BrCA and other CDKcyclin D Myc dependent malignanciesA ...

    STTR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  9. A scalable system for high throughput, chronic electrophysiology in translational rodent research

    SBC: SPIKEGADGETS, INC.            Topic: 101

    Psychiatric disorders give rise to aberrant patterns of activity within the complex neural circuits of our brainsYetthe exact nature of these abnormal patterns is often unknown to developers of new treatmentsThe goal of this project is to enable circuit oriented research of neuropsychiatric diseases using rodent disease modelsThe long term objective is to catalyze the discovery of new therapeutic ...

    STTR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  10. Artificial Salivary Gland Dental Implant

    SBC: ORAL FLUID DYNAMICS LLC            Topic: NIDCR

    Xerostomiaor dry mouthaffects approximatelyof the U Spopulationsomemillion people by causing oral discomfort and pain due to chronically dry mucosaThis condition leads to oral disease such as caries and candidiasisand has no cure or adequate treatmentMany remedial approaches have been tried with only limited successincluding the provision of fluid to the mouth via frequent sippingvarious mouthwash ...

    STTR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
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