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The Award database is continually updated throughout the year. As a result, data for FY23 is not expected to be complete until September, 2024.
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SBC: MICROFLUIDIC SYSTEMS, INC. Topic: CBD04106
PCR and antibody-based devices are currently the primary platforms for bioagent detection. PCR offers high sensitivity and specificity, but has limited effectiveness for toxins (detects residual DNA, if any, in toxin preparations) and requires thermal cycling equipment, extensive sample preparation, and complex reagents. Antibodies, which utilize relatively simple chemistry, are effective for bo ...SBIR Phase I 2004 Department of DefenseOffice for Chemical and Biological Defense
SBC: Planet Biotechnology Incorporated Topic: N/A
Our overall goal in this project is to make available inexpensive neutralizing antibodies against Botulinum neurotoxin (BoNT) in large quantity, using transgenic plants. Dr. James Marks (UC San Francisco School of Medicine) has identified murine and humansingle chain Fv (scFv) that bind non-overlapping epitopes on BoNT/A and neutralize toxin in vitro and in vivo. At present, plants offer the best ...SBIR Phase I 2003 Department of DefenseOffice for Chemical and Biological Defense
SBC: Nico Technologies Corp. Topic: CBD10103
The drug R&D cycle is long and very expensive. In many ways, this status quo can no longer be sustained. One of the reasons for such great cost is that the vast majority of drug candidates are screened out at the stages of animal and human trials. More efficient methods of testing of drugs at the stage of ex-vivo studies, which are substantially less expensive than animal and human testing cyc ...SBIR Phase I 2010 Department of DefenseOffice for Chemical and Biological Defense
SBC: DENDRITECH, INC Topic: CBD04301
Since 1993, ASZM-TEDA carbon has been the standard filtration material used by the U.S. military for protection against nerve, blister and blood agents, and other maliciously delivered air contaminants. Although ASZM-TEDA effectively removes these contaminants, alternative air filtration media are sought to ameliorate bulky, unwieldy designs necessitated by current technology. Additional improveme ...SBIR Phase I 2004 Department of DefenseOffice for Chemical and Biological Defense
SBC: Sensor Research And Development Corporation Topic: N/A
"Sensor Research and Development Corporation (SRD) proposes to develop an Automated Measurement of Breakthrough in Real-time (AMBR) prototype to test chemical protective materials. AMBR will increase the safety, efficiency, and sample throughput for fabrictests while improving data quality and expanding test capabilities. SRD will develop AMBR by integrating proven solid-state chemical agent sen ...SBIR Phase I 2002 Department of DefenseOffice for Chemical and Biological Defense
SBC: ADVANCED SENSOR TECHNOLOGIES, INC. Topic: N/A
"The US Joint Services, Federal Agencies, and state and local First Responders have expressed dissatisfaction with currently employed organophosphate (OP) sensors. They have identified the need for a new generation of sensors that is small, light-weight,and easy to use while being capable of extended operations in rugged environments. Advanced Sensor Technologies proposes to address these issues w ...SBIR Phase I 2002 Department of DefenseOffice for Chemical and Biological Defense
SBC: OPTIMETRICS, INC. Topic: N/A
N/ASBIR Phase I 2000 Department of DefenseOffice for Chemical and Biological Defense
Development of enhanced active damping system for the Marine Corps Expeditionary Fighting Vehicle (EFV)SBC: MillenWorks Topic: N04192
To meet the Marines' need for high speed ship-to-shore and land mobility, the USMC Expeditionary Fighting Vehicle (EFV) is being equipped to provide a leap-ahead improvement over the capabilities of its predecessor, the 30-year old Amphibious Assault Vehicle (AAV). A critical component of improving the EFV's lethality and survivability is to greatly increase speeds across land. While the EFV's t ...SBIR Phase I 2005 Department of DefenseSpecial Operations Command
SBC: KUMETRIX, INC. Topic: N/A
The proposed work will develop a silicon microchip containing an array of synthetic globular DNA affinity recognition elements selected for binding pathogens, toxins, or other protein-based biothreats to enable their detection in the field. For readout, aSBIR Phase I 2003 Department of DefenseOffice for Chemical and Biological Defense
SBC: INNOVATIVE SURVIVABILITY TECHNOLOGIES Topic: N/A
IST is proposing the development of a miniature chemical agent detection device that is based on using infrared energy absorption to detect the presence of toxic materials. The detection of toxic chemicals is possible if the vapors pass between a source ofinfrared energy and a sensor capable of measuring the thermal change associated with the absorption of infrared energy at specific frequencies. ...SBIR Phase I 2003 Department of DefenseOffice for Chemical and Biological Defense