Award Data

The proposed work will develop a silicon microchip containing an array of synthetic globular DNA affinity recognition elements selected for binding pathogens, toxins, or other protein-based biothreats to enable their detection in the field. For readout, a

Due to the lack of consistency in existing automated methods for assigning VNIIRS levels to motion imagery, and the overwhelming human resources required to manually assign levels, a new method of automated/semi-automated VNIIRS assessment is needed. In recent years, advancements in deep learning have provided solutions to previously intractable computer vision problems. In many cases, automated d ...

ATA Engineering, Inc., (ATA) proposes to develop and demonstrate a multiphysics framework for the radar cross-section (RCS) analysis of an ablating hypersonic vehicle in an ionized plasma flow field. ATA has developed a software toolset, known as the Multiphysics Engine, capable of modeling many of these hypersonic phenomena. It couples state-of-the-art solvers for CFD (Loci/CHEM), ablation (CHAR) ...

Development of single use, freeze-dried PCR reagents for use with the Idaho Technology Ruggedized Advanced Pathogen Identification Device (RAPIDT system) or other commercially available real-time PCR devices is proposed. These reagents will have extendedstability at ambient temperature thus allowing sensitive PCR methods to be used in non-laboratory environments for the rapid detection of biologi ...

Protein manufacturing is of paramount importance to chemical and biological defense applications. High-throughput protein purification is a critical need for rapidly scaling the target protein product. Existing purification methods primarly rely on synthetic-resin based chromatography, which is time-consuming, labor-intensive, expensive, and consequently, ill-suited for developing rapid countermea ...

WaveBand Corporation proposes to develop a new type of reduced size flexible or rigid antennas that can be mounted on the web gear or the vest of a tactical user. The requirements of both omni-directional and directional antennas as well as of multibandoperation will be satisfied within a fractal design approach. Based on the antennas, a system for directional and direction finding operations will ...

Safe and efficient air ionization and filtration technology compatible to biodefense applications is of paramount importance. Current ionization methods are energy-intensive, costly, prone to ozone generation, or inefficient, and consequently ill-suited for building protection applications. To overcome these issues, we propose to develop and demonstrate a novel bioaerosol ionization and collection ...

Current drug discovery and development programs are severely limited by the expensive animal trials and oversimplified in vitro models. Results obtained from the in vitro models are not predictive of in vivo toxicity owing to significant difference in testing from the in vivo physiological conditions. In this context, we propose to develop and demonstrate a novel microfluidic device for quantitati ...

The objective of Imaginative Technologies, LLC teamed with Yale University is to design and build a “breadboard”, real time, optical NEMS Based Methyl Salicylate Detector (MSD), capable of measuring the presence and concentration of a chemical agent simulant (methyl salicylate – MeS) beneath a protective garment. This proposed device, MSD, will be the size of a quarter so it may be comfortab ...

With the large amount of geospatially-referenced material available, an important problem for NIMA is how to organize and present that information to their customers. We propose to address this problem by building a geospatial catalog system that will notjust tell you which products are available, but also allow the user to see the actual products and the relationship to other products. This wil ...