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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. C2E2-An Orally Administered Radionuclide Decorporation Agent

    SBC: Capture Pharmaceuticals, Inc.            Topic: R

    DESCRIPTION provided by applicant Capture Pharmaceuticals Inc is developing a drug called C E for treatment of individuals who have been contaminated by radioactive transuranic elements either by accident or following a nuclear terrorism event C E is a radionuclide decorporation agent that works by binding these elements in the bloodstream and enhancing their elimination before they can b ...

    SBIR Phase II 2015 Department of Health and Human ServicesNational Institutes of Health
  2. Therapy of transplantation-induced oxidative injury using polymeric antioxidants

    SBC: CELDARA MEDICAL, LLC            Topic: 400

    DESCRIPTION provided by applicant Ischemia reperfusion I R injury during renal transplantation surgery is responsible for oxidative stresses which result in immune activation and graft rejection We are developing an antioxidative therapy that we have already shown to be highly efficacious in ameliorating damage from oxidative stress in various in vitro models as well as I R models of kidney ...

    SBIR Phase II 2015 Department of Health and Human ServicesNational Institutes of Health
  3. Development of novel anti-biofilm compounds for treating chronic wounds

    SBC: AGILE SCIENCES, INC.            Topic: NIAID

    DESCRIPTION provided by applicant Chronic wounds that fail to respond to traditional therapeutic interventions afflict millions of people each year and direct costs associated with treating these wounds are estimated at $ billion annually in the U S alone Eradication of pathogenic bacteria that have colonized chronic wounds is complicated by the propensity of these bacteria to form biof ...

    SBIR Phase II 2015 Department of Health and Human ServicesNational Institutes of Health
  4. CometChip: Development of a high throughput DNA damage assay in hepatocytes

    SBC: INTEGRATED LABORATORY SYSTEMS, LLC            Topic: 113

    DESCRIPTION provided by applicant Thousands of new industrial chemicals are produced each year Knowledge about the potential carcinogenicity of these compounds is therefore critical to public health It is well established that DNA damage can lead to the mutations that cause cancer Therefore being able to screen chemicals for their potential to damage DNA offers an effective strategy for imp ...

    SBIR Phase II 2015 Department of Health and Human ServicesNational Institutes of Health
  5. Virtual Environment Training in the Proper Use of Prescription Pain Medications

    SBC: Clinical Tools, Inc            Topic: NIDA

    DESCRIPTION provided by applicant An epidemic of addiction to prescription pain medications now causes deaths due to overdose that outnumber automobile related deaths rising admissions to hospitals and disrupted lives for both the patient and family The White House Office of National Drug Control Policy ONDCP report Epidemic Responding to Americaandapos s Prescription Drug Abuse Crisis ...

    SBIR Phase II 2015 Department of Health and Human ServicesNational Institutes of Health
  6. Synthesis and Evaluation of a Novel Anti-HIV Agent

    SBC: Kucera Pharmaceutical Company            Topic: N/A

    The long-term goal of this research is to develop a drug that is safe and effective against drug-resistant human immunodeficiency virus (HIV) infection. Several challenges confront current anti-HIV chemotherapy. The frequency of drug-resistant and multidrug-resistant HIV-1 is increasing. Toxicities associated with current HIV medications often result in the discontinuation of these therapies. Phys ...

    SBIR Phase II 2005 Department of Health and Human ServicesNational Institutes of Health
  7. Electrochemical RT Activity Assay for Measuring HIV Load

    SBC: ALDERON BIOSCIENCES, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): To address the urgent need for better treatment and diagnostic testing of HIV infected people in resource-limited settings, we propose in this Phase II SBIR to further develop an electrochemical testing system (eSystem) developed by Alderon Biosciences, Inc. for determinations of HIV viral load in clinical samples. Alderon's long-term goal is to produce, valida ...

    SBIR Phase II 2009 Department of Health and Human ServicesNational Institutes of Health
  8. A crosslinked cartilage-derived matrix for cartilage tissue engineering

    SBC: Cytex Therapeutics, Inc.            Topic: NIAMS

    DESCRIPTION provided by applicant The overall goal of the present study is to resurface a diseased femoral condyle in an ovine model of unicompartmental osteoarthritis OA For patients suffering from unicompartmental OA of the knee unicondylar knee arthroplasty UKA is an available first line treatment option that provides many potential advantages over more common total knee replacement p ...

    SBIR Phase II 2015 Department of Health and Human ServicesNational Institutes of Health
  9. Mobile Technology and Online Tools to Improve Asthma Control in Adolescents

    SBC: 3-C Institute for Social Development, Inc.            Topic: NHLBI

    DESCRIPTION provided by applicant Background and Rationale Asthma is the most common chronic illness affecting youth with prevalence and morbidity being significant among adolescents School based and web based asthma interventions have been shown to be effective with younger children Yet few interventions have been developed and tested with high school students with only one currently dep ...

    SBIR Phase II 2015 Department of Health and Human ServicesNational Institutes of Health
  10. Improving the Host Response to Implantable Glucose Sensors via Nitric Oxide Release

    SBC: CLINICAL SENSORS, INC.            Topic: 200

    DESCRIPTION provided by applicant Diabetes mellitus is a metabolic disorder afflicting more than million Americans This disease manifests itself with abnormal blood glucose levels that lead to other significant health conditions including kidney failure nerve damage blindness heart attack and stroke For more than million diabetics using insulin to control hyperglycemia frequent moni ...

    SBIR Phase II 2015 Department of Health and Human ServicesNational Institutes of Health
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