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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. HIGH PERFORMANCE NEUTRON DETECTOR FOR PROTEIN CRYSTALLOGRAPHY

    SBC: RADIATION MONITORING DEVICES, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Recently, with the increase in number of new neutron sources, stationary as well as portable, there has been growing utilization of neutrons in a similar manner. Contrary to X- and ?-rays, the probability of interaction of neutrons with matter does not depend on the atomic number but is rather irregular across the periodic table and depends on the nuclear struc ...

    SBIR Phase I 2007 Department of Health and Human ServicesNational Institutes of Health
  2. Diffused Optical Tomography using Oxygen-sensitive Luminescent Contrast Agent for

    SBC: RADIATION MONITORING DEVICES, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Molecule specific targeting and improving image contrast have been recognized as important research areas in cancer imaging. Goal of cancer diagnosis and prognosis research is to develop new imaging techniques to detect lesions with certainty in early stages so that they can be treated. Developing biomarkers, which will signal the presence and the type of lesio ...

    STTR Phase I 2007 Department of Health and Human ServicesNational Institutes of Health
  3. Instrument to Identify Hazardous Children's Products that Could Cause Lead Poison

    SBC: RADIATION MONITORING DEVICES, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Summary Lead and its compounds have been rated as one of the leading chemicals posing the greatest threat to human health. Significant amounts of lead are found in a multitude of consumer goods, ranging from electronics, household goods, to toys. In 1997, the Consumer Product Safety Commission reported identifying and taking action to reduce or eliminate the ri ...

    SBIR Phase I 2007 Department of Health and Human ServicesNational Institutes of Health
  4. High-Performance Transparent Optical Ceramic Scintillators through Nanotechnology

    SBC: RADIATION MONITORING DEVICES, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): LSO is generally recognized as the ideal scintillator for PET. It has high stopping power for 511 keV gamma rays, high light yield of over 20000 photons/MeV, and rapid decay of 32 ns. It achieves high coincidence timing resolution and energy resolution. But single crystals of LSO are difficult and expensive to grow, reproducibility is poor, and the material is ...

    SBIR Phase I 2007 Department of Health and Human ServicesNational Institutes of Health
  5. Solid-State Photosensor for PET

    SBC: RADIATION MONITORING DEVICES, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Positron Emission Tomography (PET) is a functional imaging technique with potential to quantify the rates of biological processes in vivo. The availability of short lived positron-emitting isotopes of carbon, nitrogen, oxygen and especially fluorine allows virtually any compound of biological interest to be labeled in trace amounts and introduced into the body ...

    SBIR Phase I 2007 Department of Health and Human ServicesNational Institutes of Health
  6. High-Speed Micro CT Detector for Physiologic Studies

    SBC: RADIATION MONITORING DEVICES, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Dedicated high-resolution small animal imaging systems have recently emerged as important new tools for cancer research. Of these systems, x-ray microcomputed tomography (microCT) shows promise as a cost-effective means for detecting and characterizing soft tissue structures, skeletal abnormalities, and tumors in live animals. Existing CT systems provide high-r ...

    SBIR Phase II 2007 Department of Health and Human ServicesNational Institutes of Health
  7. HIGH RESOLUTION NUCLEAR CARDIAC IMAGING

    SBC: RADIATION MONITORING DEVICES, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Nuclear medicine imaging modalities such as single photon emission computed tomography (SPECT) and positron emission tomography (PET) are powerful, non-invasive medical imaging techniques that provide an image of the three dimensional distribution of a radionuclide in any slice through an organ under study in the body. These images allow investigation of metab ...

    SBIR Phase II 2007 Department of Health and Human ServicesNational Institutes of Health
  8. High Resolution PET Detectors for Combined PET-MR Small Animal Imaging

    SBC: RADIATION MONITORING DEVICES, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): The ideal biological imaging system would provide non-invasive, high-resolution, high-sensitivity, three-dimensional (3D) functional and anatomic images of living systems. Positron Emission Tomography (PET) offers high sensitivity to a range of biological processes through the use of targeted radiolabeled probes. Unfortunately, precise signal localization can b ...

    SBIR Phase II 2007 Department of Health and Human ServicesNational Institutes of Health
  9. Digital 2-D Neutron Detector for Protein Function Studies

    SBC: RADIATION MONITORING DEVICES, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Information on the structure and function of proteins is important for unveiling biological processes taking place on a molecular level. X-ray crystallography has been successful in determining protein structure, however, it is not well suited for analyzing hydrogen atoms and water molecules. It has been shown that the thermal neutrons are a far better tool for ...

    SBIR Phase II 2007 Department of Health and Human ServicesNational Institutes of Health
  10. SBIR PHASE I, TOPIC 239 YEAST SINGLE CHAIN ANTIBODIES AS CAPTURE REAGENTS

    SBC: ALLELE BIOTECHNOLOGY AND PHARMACEUTICALS            Topic: N/A

    N/A

    SBIR Phase I 2007 Department of Health and Human ServicesNational Institutes of Health
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