Award Data

DESCRIPTION (provided by applicant): Iron is an important co-regulator of virulence in many bacterial species including Staphylococcus aurues and Staphylococcus epidermidis both significant human pathogens. The iron dependent transcriptional regulator DtxR [diphtheria toxin repressor] originally identified in Corynebacterium diphtheriae plays a ...

DESCRIPTION (Verbatim from the Applicant's Abstract): Urethral catheters are essential in the management of many diseases and conditions yet often result in catheter associated urinary tract infections. The use of sterile closed systems, advanced infection control protocols, and antimicrobial parts has not prevented infection or the associated morbidity increase. Ad ...

Terrain data needs on the battlefield are generating greater military requirements for new, rapid feature mapping capabilities. Unfortunately, current methods are woefully inadequate to meet the needs of the modern digitized battlefield in which thecommander must have the ability to rapidly obtain accurate terrain information and topographic products. Terrain Reasoning methods will allow more ra ...

N/A

65821 Aircraft measurements of ammonia and nitric acid can provide critical information on the sources and sinks of these atmospheric nitrogen species. This is important in understanding air quality, aerosol formation, visibility, and the impact of energy production and usage on global climate change. This project will develop a compact tunable infrared laser differential absorption spectromet ...

This project concerns the development of a sensor intended to remotely monitor plant stress using active stimulation of plant chlorophyll fluorescence. The intensity and spectral band shape of leaf chlorophyll fluorescence in green plants has been linked to the physiological status of the plants and thus provides a good indicator of plant health. The proposed sensor will measure the relative inten ...

This Small Business Innovation Research Phase I (SBIR) project will develop a new class of real time aerosol mass spectrometers (AMSs) for analysis of respirable powder and liquid aerosol in pulmonary drug delivery systems. Three parameters control the effective delivery of drugs to the lungs: (1) the number density of entrained aerosol particles per unit volume of respirable fluid; (2) the partic ...

This SBIR Phase1 project will involve the development of a novel method of simultaneously measuring multiple trace chemical species in jet engine exhaust, based upon an extension of the technology of tunable diode laser (TDL) spectroscopy. We will develop and demonstrate a new means of combining the light from two or more diode lasers into a single analysis beam. This will enable a multiplication ...

High pressure ratio compressor operation is enabled by blade cooling, based on an evaporation / condensation cycle. The blade or blisk temperature is defined by the vaporization temperature of a working fluid internal to the blade, with heat transferred to an integral condenser at each blade root. This approach provides heat rejection to a cool, low pressure fluid, such as engine lubricating oil, ...

This Small Business Innovation Research (SBIR) Phase I project has as its goal the demonstration of the feasibility of an optical alloy analysis instrument based on a microchip laser excitation source. This instrument will determine elemental composition using laser-induced plasma spectroscopy (LIPS). It will have the advantage over existing portable instruments of being able to determine concentr ...