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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until April, 2020.

  1. INTRAOPERATIVE, REGIONAL MYOCARDIAL BLOOD FLOW MONITOR

    SBC: Radiation Monitoring Devices, Inc.            Topic: N/A

    CORONARY ARTERY BYPASS IS ONE OF THE MOST WIDELY PRACTICED PROCEDURES FOR THE TREATMENT OF PATIENTS WITH CORONARY ATHEROSCLEROSIS, YET A SIMPLE AND RAPID METHOD FOR ASSESSINGTHE EFFECTIVENESS OF THE PROCEDURE WHILE IT IS BEING PERFORMED IS NOT CURRENTLY AVAILABLE. IT WOULD BE EXTREMELYUSEFUL IF A DIRECT MEASUREMENT OF REGIONAL MYOCARDIAL BLOOD FLOW (RMBF) COULD BE MADE PRIOR TO THE CLOSING OF THE ...

    SBIR Phase II 1988 Department of Health and Human Services
  2. REAL TIME IMAGING SYSTEM FOR SCREENING DNA LIBRARIES

    SBC: Radiation Monitoring Devices, Inc.            Topic: N/A

    N/A

    SBIR Phase I 1988 Department of Health and Human Services
  3. RENAL BLOOD FLOW MONITOR FOR ICU PATIENTS

    SBC: Radiation Monitoring Devices, Inc.            Topic: N/A

    N/A

    SBIR Phase I 1988 Department of Health and Human Services
  4. ATTENUATION OF THE NYCBH VACCINE STRAIN OF VACCINIA

    SBC: APPLIED BIOTECH CONCEPTS, INC.            Topic: N/A

    N/A

    SBIR Phase I 1988 Department of Health and Human Services
  5. COMMUNICATION TRAINING FOR SCHIZOPHRENICS VIA VIDEODISC

    SBC: ASIP, INC.            Topic: N/A

    THE SPECIFIC AIM OF THIS PHASE 1 SBIR PROPOSAL IS TO DEVELOPA CORE LIBRARY OF VIDEODISCS WHICH CAN BE USED TO TRAIN ADULT SCHIZOPHRENICS AND THEIR FAMILIES IN COMMUNICATION SKILLS. DURING PHASE 1, THE LIBRARY WILL BE CONSTRUCTED, SOFTWARE WILL BE WRITTEN, AND A SINGLE-CASE EXPERIMENTAL DESIGN WILL BE USED TO EVALUATE THE EFFECTS OF THIS TECHNOLOGY WITH 3 ADULT SCHIZOPHRENICS. THIS TECHNOLOGY WILL, ...

    SBIR Phase I 1988 Department of Health and Human Services
  6. WEARABLE MULTICHANNEL VIBROTACTILE ARRAYS FOR THE DEAF

    SBC: AUDIOLOGICAL ENGINEERING CORPORATION            Topic: N/A

    THE LONG-TERM OBJECTIVE OF THIS STUDY IS TO MAKE AVAILABLE WEARABLE TACTILE AIDS WITH EIGHT OR MORE CHANNELS AND WITH SUITABLE PERFORMANCE, SIZE, AND CONVENIENCE CHARACTERISTICS TO MEET THE REQUIREMENTS OF THE MARKET. THE IMMEDIATE TASK IS TO ASSESS THE POTENTIAL OF A SPECIFIC TYPE OF VIBRATOR ELEMENT FOR USE IN AN INTEGRATED STIMULATOR ARRAY CONSISTINGOF EIGHT OR MORE VIBRATORS. ADDITIONALLY, A Z ...

    SBIR Phase II 1988 Department of Health and Human Services
  7. PURIFIED BOVINE HEMOGLOBIN FOR CARDIAC PRESERVATION

    SBC: BIOPURE CORPORATION            Topic: N/A

    BIOPURE CORPORATION HAS SUCCESSFULLY MANUFACTURED A POLYMERIZED BOVINE HEMOGLOBIN SOLUTION WHICH PHYSIOLOGICALLYOXYGENATES AS WELL AS OR BETTER THAN RED BLOOD CELLS. KEY PERFORMANCE CHARACTERISTICS INCLUDE BETTER 0(2)/CO(2) EXCHANGE AT THE CELLULAR LEVEL THAN FRESH HUMAN BLOOD. THE PRODUCT IS ESSENTIALLY FREE OF ENDOTOXINS, PHOSPHOLIPIDS, CLINICALLY ANTIGENIC AGENTS, PLASMA PROTEINS, LIPIDS OR OTH ...

    SBIR Phase I 1988 Department of Health and Human Services
  8. DNA PROBES FOR ANTIBIOTIC RESISTANCE IN PERIODONTITIS

    SBC: Biotechnica Diagnostics Inc            Topic: N/A

    THE USE OF ANTIBIOTIC THERAPY FOR INFECTION MANAGEMENT HAS INCREASED DRAMATICALLY IN THE AREA OF PERIODONTAL DISEASE AS AN ADJUNCT TO SCALING AND SURGERY TREATMENT. WITH THE EMERGENCE OF ANTIBIOTIC USE IN PERIODONTAL DISEASE CARE, ALMOST NO WORK HAS BEEN DONE IN ASSESSING THE DEVELOPMENT OF ANTIBIOTIC RESISTANCE IN DENTAL PLAQUE FLORA. BY DEVELOPING A DNA PROBE-BASED ASSAY FOR THE DETECTION OF ANT ...

    SBIR Phase I 1988 Department of Health and Human Services
  9. DNA PROBES FOR THE DETECTION OF PERIODONTAL PATHOGENS

    SBC: Biotechnica Diagnostics Inc            Topic: N/A

    THE ROLE OF EIKENELLA CORRODENS, FUSOBACTERIUM NUCLEATUM, AND WOLINELLA RECTA AS PATHOGENS ASSOCIATED IN DESTRUCTIVE PERIODONTAL DISEASE HAS BEEN DESCRIBED IN A NUMBER OF STUDIES USING CULTURE BASED ASSAY SYSTEMS. THE STANDARD CULTURE METHODS ARE INADEQUATE FOR THE ROUTINE DIAGNOSIS OF THESE PATHOGENS. BY DEVELOPING DNA PROBE-BASED ASSAYS FOR THE DETECTION OF THESE PATHOGENS, IT WOULD BE PRACTICAL ...

    SBIR Phase I 1988 Department of Health and Human Services
  10. DEVELOPMENT OF TRANSDERMAL ANTIHISTAMINE DELIVERY SYSTEM

    SBC: BIOTEK, INC.            Topic: N/A

    THE OVERALL OBJECTIVE OF THE PROJECT IS TO DEVELOP A TRANSDERMAL DOSAGE FORM OF THE H(1)-BLOCKER CARBINOXAMINE FOR 24-HOUR CONTROL OF ALLERGIC RHINITIS. IN PHASE I THE FEASIBILITY OF SUCH DOSAGE WILL BE TESTED. IN VITRO TRANSDERMAL PENETRATION EXPERIMENTS WITH NUDE MOUSE SKINS, AS WELL AS IN VIVO TESTS ON SHAVED RABBIT SKINS WILL BE USEDTO DETERMINE PERCUTANEOUS FLUX VALUES. FORMULATIONS OPTIMIZED ...

    SBIR Phase I 1988 Department of Health and Human Services

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