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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until April, 2020.

  1. RENAL BLOOD FLOW MONITOR FOR ICU PATIENTS

    SBC: Radiation Monitoring Devices, Inc.            Topic: N/A

    N/A

    SBIR Phase I 1988 Department of Health and Human Services
  2. ATTENUATION OF THE NYCBH VACCINE STRAIN OF VACCINIA

    SBC: APPLIED BIOTECH CONCEPTS, INC.            Topic: N/A

    N/A

    SBIR Phase I 1988 Department of Health and Human Services
  3. WEARABLE MULTICHANNEL VIBROTACTILE ARRAYS FOR THE DEAF

    SBC: AUDIOLOGICAL ENGINEERING CORPORATION            Topic: N/A

    THE LONG-TERM OBJECTIVE OF THIS STUDY IS TO MAKE AVAILABLE WEARABLE TACTILE AIDS WITH EIGHT OR MORE CHANNELS AND WITH SUITABLE PERFORMANCE, SIZE, AND CONVENIENCE CHARACTERISTICS TO MEET THE REQUIREMENTS OF THE MARKET. THE IMMEDIATE TASK IS TO ASSESS THE POTENTIAL OF A SPECIFIC TYPE OF VIBRATOR ELEMENT FOR USE IN AN INTEGRATED STIMULATOR ARRAY CONSISTINGOF EIGHT OR MORE VIBRATORS. ADDITIONALLY, A Z ...

    SBIR Phase II 1988 Department of Health and Human Services
  4. PURIFIED BOVINE HEMOGLOBIN FOR CARDIAC PRESERVATION

    SBC: BIOPURE CORPORATION            Topic: N/A

    BIOPURE CORPORATION HAS SUCCESSFULLY MANUFACTURED A POLYMERIZED BOVINE HEMOGLOBIN SOLUTION WHICH PHYSIOLOGICALLYOXYGENATES AS WELL AS OR BETTER THAN RED BLOOD CELLS. KEY PERFORMANCE CHARACTERISTICS INCLUDE BETTER 0(2)/CO(2) EXCHANGE AT THE CELLULAR LEVEL THAN FRESH HUMAN BLOOD. THE PRODUCT IS ESSENTIALLY FREE OF ENDOTOXINS, PHOSPHOLIPIDS, CLINICALLY ANTIGENIC AGENTS, PLASMA PROTEINS, LIPIDS OR OTH ...

    SBIR Phase I 1988 Department of Health and Human Services
  5. DNA PROBES FOR ANTIBIOTIC RESISTANCE IN PERIODONTITIS

    SBC: Biotechnica Diagnostics Inc            Topic: N/A

    THE USE OF ANTIBIOTIC THERAPY FOR INFECTION MANAGEMENT HAS INCREASED DRAMATICALLY IN THE AREA OF PERIODONTAL DISEASE AS AN ADJUNCT TO SCALING AND SURGERY TREATMENT. WITH THE EMERGENCE OF ANTIBIOTIC USE IN PERIODONTAL DISEASE CARE, ALMOST NO WORK HAS BEEN DONE IN ASSESSING THE DEVELOPMENT OF ANTIBIOTIC RESISTANCE IN DENTAL PLAQUE FLORA. BY DEVELOPING A DNA PROBE-BASED ASSAY FOR THE DETECTION OF ANT ...

    SBIR Phase I 1988 Department of Health and Human Services
  6. DNA PROBES FOR THE DETECTION OF PERIODONTAL PATHOGENS

    SBC: Biotechnica Diagnostics Inc            Topic: N/A

    THE ROLE OF EIKENELLA CORRODENS, FUSOBACTERIUM NUCLEATUM, AND WOLINELLA RECTA AS PATHOGENS ASSOCIATED IN DESTRUCTIVE PERIODONTAL DISEASE HAS BEEN DESCRIBED IN A NUMBER OF STUDIES USING CULTURE BASED ASSAY SYSTEMS. THE STANDARD CULTURE METHODS ARE INADEQUATE FOR THE ROUTINE DIAGNOSIS OF THESE PATHOGENS. BY DEVELOPING DNA PROBE-BASED ASSAYS FOR THE DETECTION OF THESE PATHOGENS, IT WOULD BE PRACTICAL ...

    SBIR Phase I 1988 Department of Health and Human Services
  7. DEVELOPMENT OF TRANSDERMAL ANTIHISTAMINE DELIVERY SYSTEM

    SBC: BIOTEK, INC.            Topic: N/A

    THE OVERALL OBJECTIVE OF THE PROJECT IS TO DEVELOP A TRANSDERMAL DOSAGE FORM OF THE H(1)-BLOCKER CARBINOXAMINE FOR 24-HOUR CONTROL OF ALLERGIC RHINITIS. IN PHASE I THE FEASIBILITY OF SUCH DOSAGE WILL BE TESTED. IN VITRO TRANSDERMAL PENETRATION EXPERIMENTS WITH NUDE MOUSE SKINS, AS WELL AS IN VIVO TESTS ON SHAVED RABBIT SKINS WILL BE USEDTO DETERMINE PERCUTANEOUS FLUX VALUES. FORMULATIONS OPTIMIZED ...

    SBIR Phase I 1988 Department of Health and Human Services
  8. ONE WEEK SUSTAINED RELEASE METHADONE MICROCAPSULES

    SBC: BIOTEK, INC.            Topic: N/A

    N/A

    SBIR Phase I 1988 Department of Health and Human Services
  9. PORTABLE SYSTEM FOR CONTROL OF ANTICOAGULANT THERAPY

    SBC: Biotherm, Inc.            Topic: N/A

    BIOTHERM, INC. PROPOSES TO DESIGN AND DEVELOP A PORTABLE SYSTEM, ANALOGOUS TO A HAND-HELD GLUCOSE METER, TO PERMIT RAPID, CONVENIENT BLOOD COAGULATION TESTING ON FRESHLY DRAWNSAMPLES FROM PATIENTS UNDERGOING ANTICOAGULANT THERAPY. THIS COST-EFFECTIVE SYSTEM WOULD BETTER HELP MEET THE NEEDS OF PATIENTS AND PROVIDE FOR EARLIER RELEASE FROM HOSPITALS. THE USE OF SUCH A SYSTEM IN THE PHYSICIAN'S OFFIC ...

    SBIR Phase II 1988 Department of Health and Human Services
  10. ASBESTOS TOXICITY AND CARCINOGENICITY

    SBC: BOSTON BIOTECHNOLOGY CORPORATION            Topic: N/A

    THE LONG RANGE OBJECTIVE OF THIS RESEARCH IS TO REDUCE THE TOXICITY AND CARCINOGENICITY OF ASBESTOS BY DESFERROXAMINE TREATMENT, WHICH NEUTRALIZES THE CATALYTIC ACTIVITY OF THE ASBESTOS-CONTAINED IRON. IN PHASE I OF THIS PROJECT THE POSSIBILITY THAT DESFERROXAMINE TREATMENT CAN REDUCE ASBESTOS-CAUSED SQUAMOUS METAPLASIA IN TRACHEAL ORGAN CULTURES WILL BE STUDIED. SQUAMOUS METAPLASIA IS THOUGHT TOP ...

    SBIR Phase I 1988 Department of Health and Human Services

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