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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until April, 2020.

  1. AUTOMATED FETAL MONITORING RECORDS MANAGEMENT SYSTEM

    SBC: Biomedics Inc            Topic: N/A

    THE HARD-COPY FETAL MONITOR RECORD (FMR) PRODUCED AND ANNOTATED DURING LABOR CONTAINS THE HISTORY OF THE LABOR AND IS PART OF THE PATIENTS RECORD. THE BULK AND FORM OF THE FMR IS UNACCEPTABLE FOR THE CHART, THE MEDICAL RECORDS SYSTEM, OR LONG-TERM RETENTION: ALL ARE CRITICAL TO PATIENT MANAGEMENT AS WELL AS DOCUMENTATION OF CARE PROVIDED. MICROFILMING IS EXPENSIVE, TIME CONSUMING, AND MUST BE CARE ...

    SBIR Phase II 1986 Department of Health and Human Services
  2. CURRENT EXTERNAL FETAL HEART RATE MONITORS PROVIDE VALUABLE INFORMATION.

    SBC: Biomedics Inc            Topic: N/A

    CURRENT EXTERNAL FETAL HEART RATE MONITORS PROVIDE VALUABLE INFORMATION. HOWEVER, THEY REQUIRE SKILLED ATTENTION, FREQUENT ADJUSTMENTS, ANDPATIENT RESTRAINT IN ORDER TO OBTAIN CONSISTENT RELIABLE INFORMATION. THIS IS BECAUSE THEDOPPLER SIGNAL CAN ONLY BE CAPTURED FROM A SMALL VOLUME IN THE UTERUS, AND THE FETAL HEART MOVES OUT OF THIS REGION WITH FETAL OR MATERNAL MOTION. OUR AIM IS TO DEVELOP A D ...

    SBIR Phase I 1986 Department of Health and Human Services
  3. A NEW MEMBRANE FOR ELECTROCHEMICAL AND OPTICAL SENSORS

    SBC: Electrochemical Systems, Inc.            Topic: N/A

    N/A

    SBIR Phase I 1986 Department of Health and Human Services
  4. THE GOAL OF THIS PROJECT IS TO DEVELOP AN IMPROVED METHOD FOR THE UTILIZATION OF DNA PROBES.

    SBC: Halcyon            Topic: N/A

    THE GOAL OF THIS PROJECT IS TO DEVELOP AN IMPROVED METHOD FOR THE UTILIZATION OF DNA PROBES. CURRENT METHODS ARE COMPLEX AND EXPENSIVE AND THUS NOT SUITABLE FOR MANY APPLICATIONS IN CLINICAL AND GENERAL LABORATORIES, IN FIELD APPLICATIONS, OR IN THIRD-WORLD COUNTRIES. IN PHASE I, THE FEASIBILITY OF USING SINGLE STRANDED DNA PROBES AND A TRANSITION METAL CATALYST DETECTION SYSTEM WILL BE EXAMINED.T ...

    SBIR Phase I 1986 Department of Health and Human Services
  5. OPTICAL DESIGN STUDIES WILL BE CARRIED OUT TO DEVISE AN OPTICS MODULE FOR FLOW CYTOMETRY SUCH THAT THE FLOW CHAMBER BECOMES AN INTEGRAL PART OF THE OPTICAL SYSTEM AND FLUOR- ESCENCE IS COLLECTED FOR ALMOST A FULL 4 STERIDIANS (DUAL- HEMISPHERICAL SPACE).

    SBC: IMAGE ANALYSIS, INC.            Topic: N/A

    OPTICAL DESIGN STUDIES WILL BE CARRIED OUT TO DEVISE AN OPTICS MODULE FOR FLOW CYTOMETRY SUCH THAT THE FLOW CHAMBER BECOMES AN INTEGRAL PART OF THE OPTICAL SYSTEM AND FLUOR- ESCENCE IS COLLECTED FOR ALMOST A FULL 4 STERIDIANS (DUAL- HEMISPHERICAL SPACE). AN IMPROVEMENT OF AT LEAST A FACTOR OF FOUR IN THE EFFICIENCY OF LIGHT COLLECTION OVER EXISTING DESIGNS AND BY MORE THAN AN ORDER OF MAGNITUDE OV ...

    SBIR Phase I 1986 Department of Health and Human Services
  6. THE LONG-TERM OBJECTIVE OF THIS PROJECT IS THE MOLECULAR CHARACTERIZATION (CDNA CLONING, EXPRESSION) OF MURINE AND HUMAN GENES CODING FOR A GROWTH FACTOR FOR MATURE B- LYMPHOCYTES (M-BC-GF).

    SBC: Immunex Corp            Topic: N/A

    THE LONG-TERM OBJECTIVE OF THIS PROJECT IS THE MOLECULAR CHARACTERIZATION (CDNA CLONING, EXPRESSION) OF MURINE AND HUMAN GENES CODING FOR A GROWTH FACTOR FOR MATURE B- LYMPHOCYTES (M-BC-GF). OUR APPROACH WILL BE TO CONSTRUCT A CDNA LIBRARY FROM SIZED, ACTIVE, M-BC-GF MRNA AND TO ISOLATEA FULL-LENGTH M-BD-GF CDNA BY HYBRIDIZATION WITH AN OLIGONUCLEOTIDE PROBE DEDUCED FROM PROTEIN SEQUENCE INFORMATI ...

    SBIR Phase I 1986 Department of Health and Human Services
  7. THE LONG-TERM OBJECTIVE OF THIS PROJECT IS THE MOLECULAR CHARACTERIZATION (CDNA CLONING, EXPRESSION) OF MURINE AND HUMAN GENES CODING FOR A GROWTH FACTOR FOR PREMATURE B- LYMPHOCYTES (PRE-BC-GF).

    SBC: Immunex Corp            Topic: N/A

    THE LONG-TERM OBJECTIVE OF THIS PROJECT IS THE MOLECULAR CHARACTERIZATION (CDNA CLONING, EXPRESSION) OF MURINE AND HUMAN GENES CODING FOR A GROWTH FACTOR FOR PREMATURE B- LYMPHOCYTES (PRE-BC-GF). THE APPROACH WILL BE TO CONSTRUCT A CDNA LIBRARY FROM SIZED, ACTIVE, PRE-BC-GF MRNA AND TO ISOLATE A FULL-LENGTH PRE-BC-GF CDNA BY HYBRIDIZATION WITH AN OLIGONUCLEOTIDE PROBE DEDUCED FROM PROTEIN SEQUENCE ...

    SBIR Phase I 1986 Department of Health and Human Services
  8. NMR DATA PROCESSING AND MOLECULAR MODELING WORKSTATION

    SBC: Infinity Systems Design, Inc.            Topic: N/A

    THE ADVENT OF NEW TECHNIQUES AND MODERN EQUIPMENT FOR NUCLEAR MAGNETIC RESONANCE (NMR) RESEARCH MAKES NMR THE METHOD OF CHOICE FOR STUDYING THE STRUCTURE AND DYNAMICS OF BIOLOGICAL MOLECULES IN SOLUTION. MODERN NMR EXPERIMENTS CAN YIELD A STAGGERING AMOUNT OF STRUCTURAL INFORMATION, WHICH MAKES THE TECHNIQUE VERY ATTRACTIVE BUT LEADS TO PROBLEMS PROCESSING THE DATA. SINCE NMR SPECTROMETERS ARE VER ...

    SBIR Phase II 1986 Department of Health and Human Services
  9. RECENT INFORMATION SUGGESTS THAT THE MEXICAN HISPANIC POPU- LATION IN THE UNITED STATES IS AT HIGH RISK FOR CORONARY HEART DISEASE, DIABETES MELLITUS, AND SOME SITE-SPECIFIC FORMS OF CANCER.

    SBC: Kensal Consulting            Topic: N/A

    RECENT INFORMATION SUGGESTS THAT THE MEXICAN HISPANIC POPU- LATION IN THE UNITED STATES IS AT HIGH RISK FOR CORONARY HEART DISEASE, DIABETES MELLITUS, AND SOME SITE-SPECIFIC FORMS OF CANCER. OTHER DATA INDICATE THAT SOCIOCULTURAL FACTORS MAY PLAY A PRIMARY ROLE IN DETERMINING THE HEALTH STATUS OF THIS POPULATION. THE MOST IMPORTANT FACTORS IMPLICATED ARE DIET-RELATED KNOWLEDGE, ATTITUDES, AND BEHA ...

    SBIR Phase I 1986 Department of Health and Human Services
  10. IT IS LAWRENCE MEDICAL SYSTEMS' HYPOTHESIS THAT NONINVASIVE DETERMINATION OF CARDIAC OUTPUT WILL IDENTIFY THE PATHOPHY- SIOLOGIC BASIS OF A PATIENT'S HYPERTENSION.

    SBC: Lawrence Medical Systems Inc            Topic: N/A

    IT IS LAWRENCE MEDICAL SYSTEMS' HYPOTHESIS THAT NONINVASIVE DETERMINATION OF CARDIAC OUTPUT WILL IDENTIFY THE PATHOPHY- SIOLOGIC BASIS OF A PATIENT'S HYPERTENSION. THAT IS, WHETHER THE HYPERTENSION IS DUE TO ELEVATED CARDIAC OUTPUT, INCREASED SYSTEMIC VASCULAR RESISTANCE, OR BOTH. THIS KNOWLEDGE WILL BE USEFUL IN SELECTING THE BEST ANTIHYPER- TENSIVE REGIMEN FOR INDIVIDUAL PATIENTS, RESULTING IN B ...

    SBIR Phase I 1986 Department of Health and Human Services

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