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The Award database is continually updated throughout the year. As a result, data for the given year is not complete until April of the following year. Annual Reports data is a snapshot of agency reported information for that year and hence might look different from the live data in the Awards Information charts.

  1. High Content Screening for Muscular Dystrophy

    SBC: MYOMICS, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Myomics' drug screening technology to be developed in this Phase 1 SBIR project for Duchene muscular dystrophy (DMD) is based upon an in vitro skeletal muscle tissue force measurement technique for high content screening (HCS) of compounds to attenuate muscle weakness. Currently, there are few drugs besides Prednisone which are used clinically to slow muscle we ...

    SBIR Phase I 2007 Department of Health and Human Services
  2. SBIR Phase II: Physiologic High Throughput Screening of Bioengineered Tissues

    SBC: MYOMICS, INC.            Topic: BT

    This Small Business Innovation Research (SBIR) Phase II research develops an innovative high-throughput/high content drug screening platform that utilizes three-dimensional human skeletal muscle tissue constructs that mimic in vivo skeletal muscle to quantify muscle force generation. Significant demands exist for new drugs to treat contractility disorders involving skeletal muscle. Myomics' propos ...

    SBIR Phase II 2007 National Science Foundation
  3. Hybridization-Assisted Nanopore Sequencing

    SBC: NABSYS, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): The rationales for the development of technology that will enable extremely cheap, high speed sequencing are well established. Chief among these is the enablement of personalized medicine. There are currently in development several technologies that promise to markedly decrease the cost of sequencing a human genome. It is unclear, however, that any of these wil ...

    SBIR Phase I 2007 Department of Health and Human Services
  4. Promoting Health During Pregnancy: A Multiple Behavior Expert System Intervention

    SBC: Pro-Change Behavior Systems Inc            Topic: N/A

    DESCRIPTION (provided by applicant): Low birthweight and preterm birth are unfavorable birth outcomes that translate into serious and costly health issues, including infant morbidity and infant mortality. Research demonstrates that the health behaviors of pregnant women are associated with not only birth outcomes, but also the future health of the child. The goal of this research is to develop an ...

    SBIR Phase I 2007 Department of Health and Human Services
  5. Bioprocessing of Plasma Therapeutic Proteins using Sequential Affinity Monolithic

    SBC: PROTHERA BIOLOGICS, LLC            Topic: N/A

    DESCRIPTION (provided by applicant): Plasma fractionation is one of the largest industry segments in global therapeutic protein manufacture. The United States plays an important role in this industry since it represents the largest plasma collection and manufacturing base that accounts for more than 50% of the world supply of plasma. Even though more than 22 million liters of plasma are collected ...

    SBIR Phase I 2007 Department of Health and Human Services
  6. Portable Interactive 3D Virtual Reality Training System

    SBC: PURVIS Systems Incorporated            Topic: N07T014

    PURVIS Systems proposes to team with the University of Rhode Island to research the feasibility of designing and developing a functional prototype of a "Portable Interactive 3D Virtual Reality (VR) Training System". This training tool is for submarine or classroom use and provides remote, realistic training scenarios using interactive, three-dimensional, Virtual Reality environments and tools, suc ...

    STTR Phase I 2007 Department of DefenseNavy
  7. Development of a Functional Health CAT for Managing Obesity

    SBC: QUALITYMETRIC, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Development of a Functional Health CAT for Managing Obesity Abstract In recent decades the prevalence of obesity has increased dramatically in the United States, causing a great burden for the individual and society. Although behavioral factors are among the most prominent causes of obesity and numerous weight management programs are currently offered, few prac ...

    SBIR Phase I 2007 Department of Health and Human Services
  8. Development of a Computerized Adaptive Test for Patients with HIV Infection

    SBC: QUALITYMETRIC, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): With improvements in the survival of patients with HIV and AIDS, maximizing patients' functional status and well-being is increasingly an important treatment goal. Existing instruments for assessing HIV patients' self- reported functional status and well-being are fixed-form static questionnaires. They have limitations in range and precision that can restrict t ...

    SBIR Phase I 2007 Department of Health and Human Services
  9. Computerized Adaptive Assessment of Asthma Impact

    SBC: QUALITYMETRIC, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Several recent initiatives have emphasized the importance of developing and testing new technologies to measure patient-reported outcomes (PRO). PRO measures for asthma can be substantially improved using item response theory (IRT), and competing objectives of more practical and more precise assessments can be achieved over a wide range of severity levels using ...

    SBIR Phase II 2007 Department of Health and Human Services
  10. Molecular Shape Detection for Chemical Analysis

    SBC: RYON TECHNOLOGIES, INC            Topic: A07T012

    Mass spectrometry is a technology with wide-ranging applications in defense and homeland security. The technique is widely applicable and exceedingly sensitive, but for many molecules there can be ambiguities regarding the isomeric and conformeric form. As the number of atoms in a molecule increases, the number of stable isomers raises dramatically. Recent research has shown that the binding en ...

    STTR Phase I 2007 Department of DefenseArmy

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