Award Data

A recent study of battlefield casualties found that over 90% of potentially survivable mortality cases were associated with hemorrhage. It is critical to maintain fluids and prevent hemorrhagic shock as soon as possible after the injury. However, medics must plan for and carry these bulky solutions to the point of injury, and additional casualties could exhaust limited available supplies. Mainstre ...

To address the DHP need for a deployable, controlled hypothermia device, Physical Optics Corporation (POC) will further improvise on our Fast and Smart Cooling Equipment for Enhanced Neuroprotection (FASCOOL) based on research results of a previously funded DARPA SBIR. The FASCOOL program will leverage findings from that program and augment the device by adding a new feedback/control mechanism to ...

Our proposal specifically addresses the stated requirements of the solicitation: we will develop and deploy tools, methods, and models for the research and design of a unique system referred to as BrainCool. The EDAptive BrainCool solution builds on previous ECI knowledge and technologyitself innovativeto solve the problem of Brain Temperature Management. Innovations required include measuring bra ...

Traumatic brain injury (TBI) impacts over two million Americans annually, and is the signature injury of the Iraq and Afghanistan conflicts. Therapeutic hypothermia is a promising neuroprotective technique for treating TBI, but reduced body temperature is a threat to soldiers in military operations with multiple injuries. Mainstream has proposed a novel vapor compression cooling system that overco ...

Non-compressible Torso Hemorrhage (NCTH) is the leading cause of preventable battlefield death for many decades.In recent years, there has been a resurgence of interest in intravascular occlusive technologies as a solution for this persistent cause of death in both civilian and military sectors.The Resuscitative Endovascular Balloon Occlusion of the Aorta (REBOA) device is the current state of the ...

Selective Aortic Arch Perfusion (SAAP) was invented by Manning specifically to treat both traumatic and non-traumatic/medical cardiac arrest. SAAP uses a descending aortic arch balloon occlusion catheter to selectively perfuse the heart and brain to restore intrinsic cardiac function and limit neurological injury. In hemorrhage-induced traumatic cardiac arrest (HiTCA), aortic occlusion controls su ...

Hyperkalemia continues to be a concern when treating combat casualties. Current hemodialysis systems use a dialysate in a membrane contactor to replicate the function of the kidney by removing the toxins, excess fluid and the minerals. The dialysis machines used in hemodialysis centers are bulky. There are home dialysis machines that are smaller but not person portable and weighing about 70lbs.Sim ...

Defense Health Program (DHP) seeks to develop a new and innovative medical device tailored to prevent or treat accumulation of blood in the pleural space after chest trauma or surgery (i.e. retained hemothorax). Critical Innovations, NeoMatRx, Milestone Strategies, and The FDA Group, in addition to consultant Captain David Plurad, MD, FACS (USN, Ret.), have formed a team of medical device experts ...

The advancements in body armor combined with better combat casualty care have greatly increased the survival rate of soldiers suffering battlefield trauma injuries. The increased survivability, however, has resulted in an increase of wounded warriors being sent home with severe injuries that ultimately reduce their quality of life post-treatment, especially those with severe damage to genitourinar ...

GU injuries have been amplified as dismounted patrols have increased and frequent exposure to improvised explosive devices (IEDs) in recent conflicts. Penile injury incurred on the battle field increases the complication of performing replantation surgery. Generally, more time is required beyond the available 6 hours of biological time after dissection for autogenous reconstruction. Promisingly, h ...