Award Data

DESCRIPTION (provided by applicant): Cerebral edema (and its counterpart in the spinal cord) is a major contributor to the damage caused by stroke, traumatic brain injury, traumatic spinal-cord injury, and bacterial meningitis. Stroke alone is the third leading cause of death in the USA and the leading cause of disability. Unfortunately, few treatment options are available for cerebral and spinal- ...

DESCRIPTION (provided by applicant): In chronic wounds, numerous factors contribute to the diminished healing. Wound healing constituents, including heparan sulfate proteoglycans and numerous growth factors, are essential to normal skin wound healing. Several key growth factors such as FGF, VEGF, and PDGF require heparan sulfate-like polymers as co- receptors or co-activators for growth factor act ...

Approximately 2 million infections are acquired in hospitals annually with a major source of bacterial contamination being frequently touched common surfaces. This problem also exists for Combat Surgical Hospitals. Current anti-bacterial coatings are not suitable for these environments because of human toxicity, low activity, and/or poor adhesion. The goal of this project is to develop a low cost, ...

This Small Business Innovation Research Phase I project will establish the feasibility of producing a flexible, highly transparent polyimide film that is thermally stable, has a high glass transition, displays near zero birefringence and a low coefficient of thermal expansion (CTE). This material is designed for use as a flexible flat panel display substrate. No available material displays all of ...

High operating temperatures and harsh environments have caused a significant decrease in elastomeric material durability for military vehicles. ARDL will be using recent advances in material technology, testing methodology, processing, and design-analysis concepts to develop the material model and meet the project goal. Material choices and test designs will be established based on the requirement ...

For Phase I, an ultra low power, high performance microprocessor core using a combination of double-gated and independent double-gated Flexfet™ SOI CMOS technology from American Semiconductor will be designed to address the requirements of military and space communication systems. High integration feasibility using Flexfet technologies followed by confirmation of the power and performance improv ...

Improvements in silicon-on-insulator (SOI) technology have resulted in development of monolithic chip designs for radiation image sensors and particle detectors by facilitating the use of the handle silicon layer for the detectors and the SOI layer for the readout circuits. Unfortunately, even the most advanced SOI-based imagers are still limited in effectiveness due to threshold (Vt) shifts when ...

Our proposed effort will be used to determine the feasibility of a deeply-throttleable aerospike engine that maintains constant specific impulse performance, regardless of the throttle setting. The design incorporates technology previously demonstrated under another SBIR, but extends it through incorporation of an aerospike nozzle.

In our proposed effort, we intend to perform high temperature (100-200 Deg C) characterization of an ultra-advanced heat pipe to determine feasibility of using it in high temperature space radiators. In previous work, we have shown that the so-called "Qu Tube" achieves exceptionally high thermal transport rates at lower temperatures. BENEFIT: Our innovation will significantly reduce the size of ...

The Radiation Test Environment Simulation Toolkit (RadTEST) is capable of flowing down radiation environment requirements to the development of test plans, post-test analysis, and test reports. It''s capabilities include: --Access to RadCat Parts and Materials Database --Test Facility Catalog with Radiation Spectra --Interface with Radiation Transport Codes --Electronic Test Plan Generation --Ele ...