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Development of a long-acting, injectable controlled release butyrylcholinesterase formulation using predictive modeling.SBC: Qrono, Inc. Topic: CBD13107
Elevated levels of human butyrylcholinesterase (BuChE) confer protection from chemical warfare nerve agents and other organophosphorous chemicals. As a prophylactic, the key to enabling this protection is the ability to maintain elevated concentrations of BuChE in the plasma for days or weeks. Thus far, plasma-derived and PEGylated recombinant forms of BuChE have been tested in humans. However, ...SBIR Phase I 2013 Department of DefenseOffice for Chemical and Biological Defense
SBC: MARINE1 LLC Topic: SOCOM10005
Marine 1, LLC and senior business partner Moxahela Enterprises, LLC are pleased to present this proposal for the US Special Operations Command (USSOCOM) Small Business Innovative Research (SBIR) topic number SOCOM10-005 for high speed combatant craft automated ride control. USSOCOM has identified the need for a lightweight, automated ride control system that will model and predict craft motion to ...SBIR Phase I 2010 Department of DefenseSpecial Operations Command
SBC: GLOBAL MILITARY EXPERT CONSULTING AND INSTRUCTION, LLC Topic: SOCOM10008
GMECI proposes to combine existing commercial template matching and feature extraction algorithms with existing military EOIR sensor technology, to automatically highlight in real time friendly forces on existing displays. The proposed technology, Blue force Designated Optical Templates (BlueDOTs) will allow automatic computer recognition and highlighting to discern among individual, customized lo ...SBIR Phase I 2010 Department of DefenseSpecial Operations Command
SBC: SciSwift LLC Topic: SOCOM18004
This proposal is for a feasibility study on the creation of an integrated software development platform to demonstrate how software projects can rapidly, reliably, and securely be created nearly on-demand. Furthermore, this study attempts to solve the rating and vetting of developers problem, based on their code quality, efficiency, and work product, using a novel machine learning system.The study ...SBIR Phase I 2018 Department of DefenseSpecial Operations Command
SBC: Nico Technologies Corp. Topic: CBD10103
The drug R&D cycle is long and very expensive. In many ways, this status quo can no longer be sustained. One of the reasons for such great cost is that the vast majority of drug candidates are screened out at the stages of animal and human trials. More efficient methods of testing of drugs at the stage of ex-vivo studies, which are substantially less expensive than animal and human testing cyc ...SBIR Phase I 2010 Department of DefenseOffice for Chemical and Biological Defense
SBC: GUILD ASSOCIATES INC Topic: CBD10106
Guild Associates, Inc. proposes to develop and evaluate an active electrochemical sensor based residual life indicator (RLI) for adsorptive carbon filters. The sensing system of the RLI will operate by analyzing the electrochemical state of the carbon within the filter and evaluate the remaining adsorptive reactive capacities of the filter. The sensor design will be challenged against an array of ...SBIR Phase I 2010 Department of DefenseOffice for Chemical and Biological Defense