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The Award database is continually updated throughout the year. As a result, data for FY22 is not expected to be complete until September, 2023.
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AC Impedance Sensor for Collective Protection Filter Residual Life IndicatorSBC: GUILD ASSOCIATES INC Topic: CBD10106
Guild Associates, Inc. proposes to develop and evaluate an active electrochemical sensor based residual life indicator (RLI) for adsorptive carbon filters. The sensing system of the RLI will operate by analyzing the electrochemical state of the carbon within the filter and evaluate the remaining adsorptive reactive capacities of the filter. The sensor design will be challenged against an array of ...SBIR Phase I 2010 Department of DefenseOffice for Chemical and Biological Defense
A Novel Microfludic Device for Drug Toxicity StudiesSBC: CFD RESEARCH CORPORATION Topic: CBD10103
Current drug discovery and development programs are severely limited by the expensive animal trials and oversimplified in vitro models. Results obtained from the in vitro models are not predictive of in vivo toxicity owing to significant difference in testing from the in vivo physiological conditions. In this context, we propose to develop and demonstrate a novel microfluidic device for quantitati ...SBIR Phase I 2010 Department of DefenseOffice for Chemical and Biological Defense
Microfluidic High-throughput Platform for Determining of Kinetic Constants of Enzyme VariantsSBC: CFD RESEARCH CORPORATION Topic: CBD10107
Molecular biology techniques allow generating combinatorial libraries of large number of enzyme variants. However, there is currently no technology available for screening the enzyme libraries for identifying variants with improved activity for the substrate. We propose to develop a novel, microfluidic, high-throughput platform for determining kinetic constants of enzyme variants and identifying v ...SBIR Phase I 2010 Department of DefenseOffice for Chemical and Biological Defense
An automated, high throughput, resin-free device for large scale protein purificationSBC: CFD RESEARCH CORPORATION Topic: CBD12102
Protein manufacturing is of paramount importance to chemical and biological defense applications. High-throughput protein purification is a critical need for rapidly scaling the target protein product. Existing purification methods primarly rely on synthetic-resin based chromatography, which is time-consuming, labor-intensive, expensive, and consequently, ill-suited for developing rapid countermea ...SBIR Phase I 2013 Department of DefenseOffice for Chemical and Biological Defense
A Novel, Aerodynamics-augmented Continuous Ionization System for Electrostatic Collection of BioaerosolsSBC: CFD RESEARCH CORPORATION Topic: CBD12107
Safe and efficient air ionization and filtration technology compatible to biodefense applications is of paramount importance. Current ionization methods are energy-intensive, costly, prone to ozone generation, or inefficient, and consequently ill-suited for building protection applications. To overcome these issues, we propose to develop and demonstrate a novel bioaerosol ionization and collection ...SBIR Phase I 2013 Department of DefenseOffice for Chemical and Biological Defense
Novel Circulating RNA-based Markers as Diagnostic Biomarkers of Infectious DiseasesSBC: CFD RESEARCH CORPORATION Topic: CBD18A001
In resource limited settings, rapid and accurate diagnosis of infections is critical for managing potential exposures to highly virulent pathogens,whether occurring from an act of bioterrorism or a natural event. This is especially important for hard to detect intracellular bacterial andalphavirus infections, that overlap symptomatically and often treated empirically due to a lack of reliable and ...STTR Phase I 2018 Department of DefenseOffice for Chemical and Biological Defense