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SBC: POINT DESIGNS, LLC Topic: NICHD
The Point DigitA Ratcheting Prosthetic Finger UsingAdvanced Rapid Manufacturing Technology Project SummaryAbstract The goal of the proposed project is to develop and commercialize a purely mechanicalratcheting prosthetic fingerthe Point Digitwhichhas an industry leading strength to weight ratiocan be operated unilaterallyone handedoffers anatomical rotation and flexion around the patient s metacar ...STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
SBC: MICRONET SOLUTIONS INC. Topic: DMEA18B001
The objective of this proposal is to demonstrate the feasibility of producing an automated delayering and imaging system with end point detection, material density detection with built in neural network error correction. This process, coined fast Automated Delayering-Image Capture System (ADICS) leverages off of the existing Pix2Net which is a proven automated imaging 3D microchip reconstruction ...STTR Phase I 2019 Department of DefenseDefense Microelectronics Activity
SBC: SPECTRAL ENERGIES LLC Topic: DMEA18B001
The proposed research and technical objectives in this project deal with computerized automatic delayering and polishing system that would be applicable to both commercial and government semiconductor device research and development with applications including Failure Analysis (FA), Fault Isolation (FI), and Reverse Engineering (RE) of semiconductor microelectronic devices. This project could hel ...STTR Phase I 2019 Department of DefenseDefense Microelectronics Activity
SBC: Inovasc, LLC Topic: 300
ABSTRACT Although arteriovenous fistulae AVFs are the preferred mode of dialysis vascular access over fail to mature in that they do not develop an adequate blood flow or diameter to support hemodialysis This results in a very significant clinical morbidity and economic cost At a pathogenetic level AVF maturation failure is due to a small vessels b bad non laminar hemodynamic pr ...STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
SBC: Nitinetics LLC Topic: NIDCD
DESCRIPTION provided by applicant Of all the hundreds of types of synthetic middle ear implants that are used in surgery approximately of these are rejected by the body These include total ossicular replacement prostheses TORPs and partial ossicular replacement prostheses PORPs TORPs are used in general when during surgery it is noted that the malleus incus and stapes are all absen ...STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
SBC: O2 RegenTech LLC Topic: 200
DESCRIPTION provided by applicant Oxygen plays a significant role in wound healing and maintaining elevated tissue oxygenation levels are an important factor in the dermal healing response Specifically non healing diabetic chronic wounds defined as lasting andgt weeks often show devastatingly low oxygen concentrations as low as mmHg oxygen partial pressure In the USA there are more ...STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
SBC: ASSUAGE PHARMACEUTICALS, INC. Topic: NIAAA
PROJECT SUMMARY Alcohol addiction and disorders associated to excessive alcohol use are a serious public health problem in the United States and in other parts of the world Current pharmacotherapies for the treatment of these disorders show limited efficacy Preclinical and clinical findings point to nicotinic acetylcholine receptors nAChRs as an alternative promising target for the developmen ...STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
SBC: EXSCIEN CORPORATION Topic: NIDDK
DESCRIPTION provided by applicant Insulin resistance IR also known as metabolic syndrome is tied to obesity and is associated with numerous modern health problems including the growing problems of type diabetes and cardiovascular disease The growing health economic and social burdens of these conditions calls for the need to develop drug treatments for IR We know from multiple lines of ...STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
SBC: Decimal, LLC Topic: 102
Project Summary Abstract Electron beam therapy EBT using MeV beams provides effective radiation treatment for superficial cancers depthandlt cm As many as of radiotherapy patients in USA annually are eligible for electron therapy for some portion of their treatment making it the second most used external beam modality As many as of these electron patients ...STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
SBC: COGMETRIC LLC Topic: NIA
ABSTRACT Detecting change in neuropsychological functioning over time is critical for proper diagnosis and management of many neurological psychiatric and psychological conditions It is well documented that most commonly used cognitive assessments produce significant retest effects such as practice and regression to the mean effects Retest effects can cause substantial changes in test score ...STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health