Award Data

Existing clinical decision support systems (CDSS) for TBI/PTSD are not well integrated with clinical pathways, terminologies/codes, and/or electronic medical records. Further, these CDSS do not leverage the latest computing technologies such as cloud computing, speech recognition, mobile computing and NLP. In particular, latest advances in machine learning / predictive analytics are not utilized. ...

The goal of this Phase I project is to develop an engineering plan and to create a prototype for a mobile, cloud-based expert system to aid in diagnosis, decision support and predictive analytics to improve clinical outcomes for veterans, soldiers, and their families with traumatic brain injury (TBI) and posttraumatic stress disorder (PTSD). Lifecom, Inc. is a health information technology compan ...

To provide better healthcare to PTSD patients, there is a strong need to develop a powerful PTSD CDSS based on evidence-based treatment strategies, acting as an anytime virtual assistant for PTSD professionals, Primary Care Physicians (PCP) and residents. To address this critical need, Intelligent Automation, Inc., proposes to develop an innovative Virtual PTSD Clinical Assistant with Cloud Comput ...

We propose to design and develop a Cohort Development and Analysis Toolkit (CDAT) that will assist clinicians, practice administrators and public health professionals in comparing the effectiveness of different clinical practices, including preventive and treatment modalities. The overall goal of CDAT is to facilitate comparative effectiveness research and evidence-based practice without the nece ...

To meet the DHP"s need for a freestanding, lightweight, compact, portable trap to collect a broad spectrum of flying disease vectors, Physical Optics Corporation (POC) proposes to develop a Multi Configurable Trap (McTrap), based on a combination of trap features that have proven effective in collecting different species; a solar-powered internal rechargeable power source; and a lightweight CO^2 s ...

With this Phase I SBIR project we intend to develop technical solutions to the primary issues limiting the feasibility of a stand-alone real-time balance feedback device. We intend to develop a technique that uses multiple sensors to estimate the orientation of the user"s body segments in the presence of real world disturbances. The effort will develop and validate techniques for accurate real-tim ...

The goal of this Phase I SBIR proposal is to develop and evaluate a new antimicrobial coating to augment infection control in medical care settings. Laboratory and clinical studies have shown that bacteria can survive for weeks on items found in hospital patient rooms. Such items and are believed to play a role in the transmission of infectious agents. Reducing the number of microorganisms survivi ...

To address the DHP need for a controlled, target-specific delivery system for topical treatment of peripheral neuropathy (PN), Physical Optics Corporation (POC) proposes to develop Nano Therapeutics for Peripheral Neuropathy (NATPEN). The NATPEN will include a nanocarrier (NC) loaded with specific drugs, a biocompatible gel to contain the NC, and a microneedle patch for transdermal delivery of the ...

We propose to identify biomarkers associated with pain and design a biomarker assay that can be used by scientists to study pain in many different diseases/conditions. Two biomarker discovery strategies will be used to identify candidate biomarkers in diseases associated with chronic pain. Diseases include fibromyalgia, rheumatoid arthritis and osteoarthritis. From a literature search, we have ...

Current therapies to prevent scar formation and contracture of burns are minimally effective. QuickMed Technologies (QMT) proposes to develop an advanced therapy to enhance healing and prevent contraction of burn scars by combining the advanced prototype BURN-PLUS dressing with Endoform dermal template. BURN-PLUS is an occlusive island dressing with an adhesive apron bonded onto a super absorben ...