Award Data

To address the DHP need for a controlled, target-specific delivery system for topical treatment of peripheral neuropathy (PN), Physical Optics Corporation (POC) proposes to develop Nano Therapeutics for Peripheral Neuropathy (NATPEN). The NATPEN will include a nanocarrier (NC) loaded with specific drugs, a biocompatible gel to contain the NC, and a microneedle patch for transdermal delivery of the ...

We propose to identify biomarkers associated with pain and design a biomarker assay that can be used by scientists to study pain in many different diseases/conditions. Two biomarker discovery strategies will be used to identify candidate biomarkers in diseases associated with chronic pain. Diseases include fibromyalgia, rheumatoid arthritis and osteoarthritis. From a literature search, we have ...

Current therapies to prevent scar formation and contracture of burns are minimally effective. QuickMed Technologies (QMT) proposes to develop an advanced therapy to enhance healing and prevent contraction of burn scars by combining the advanced prototype BURN-PLUS dressing with Endoform dermal template. BURN-PLUS is an occlusive island dressing with an adhesive apron bonded onto a super absorben ...

The Air Force Medical Modeling & Simulation Program has a need for synthetic tissue trainers that replicate live tissues and anatomy. Project targets replacing expensive and often objectionable live animal training. The work will be based on the trainer that was produced during Phase I. The developed trainers will replicate segments of human anatomy and will comprise multiple modular components ...

The objective of this proposal is to develop an alternative to the tuberculin test and interferon- & #61543; & #61472;release assays for the diagnosis of active and latent tuberculosis. Toward this end, a rapid lateral flow test based on the detection of blood antibodies specific to Mycobacteria tuberculosis antigens will be devised for the serodiagnosis of active and latent TB. Selected and highl ...

Fall-related events are the leading cause for injury deaths among people 65 years and older. Blast related balance dysfunction is a significant problem the military. Recent advances in Micro-Electrical-Mechanical Systems (MEMS) have made accessible a variety of extremely small, rugged, reliable, low power consumption, and inexpensive sensors of acceleration and pressure. A collection of these devi ...

Good hearing is critical to understanding verbal communications, and to auditory situational awareness in military training and on the battlefield. Also, hearing protection is critical to the health and safety of those exposed to hazardous noise. In veteran"s compensation cases, Tinnitus and Hearing loss are the two most common disabilities awarded by the VA. Exposure to high noise levels, both ...

To address the Army Medical Research and Material Command"s need for closed-loop anesthesia system Physical Optics Corporation (POC) proposes to develop a new Intelligent Sensor for Closed Loop Anesthesia Delivery (iSCAD) system based on a novel optical spectroscopy technique and a multisensor fusionbased control algorithm. The key innovation in the iSCAD is its novel system design that allows acc ...

To address the DHP need for a biometric model to address dismounted complex blast injury of the pelvis, abdomen, and genitals, Physical Optics Corporation (POC) proposes to develop a new Pelvic Model with multi-Sensory Data Acquisition (ELVIS). This proposed model is based on the combined development of a numerical model for blast effect prediction for different impact forces and an anatomically c ...

Thermal injury is common in military conflicts due to primarily to the widespread use of explosive devices. Burns can produce scars that are excessive, physically debilitating and functionally damaging. There is a critical need for an effective product that can control bacterial contamination and prevent colonization, mitigate inflammation, and diffuse to or reach necrotic and damaged tissue resul ...